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Activation of the JNK signaling pathway: Breaking the brake on apoptosis

BioEssays, 2003-01, Vol.25 (1), p.17-24

Lin, Anning

2003

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Role of JNK activation in apoptosis： A double-edged sword

Cell research, 2005, Vol.15 (1), p.36-42

2005

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The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation

Immunity (Cambridge, Mass.), 2021-06, Vol.54 (6), p.1168-1185.e8

2021

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Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.E10682-E10691

2018

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Multi-Omics Analysis in β-Thalassemia Using an HBB Gene-Knockout Human Erythroid Progenitor Cell Model

International journal of molecular sciences, 2022-03, Vol.23 (5), p.2807

2022

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Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (31), p.9644-9649

2015

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Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice

STAR protocols, 2021-12, Vol.2 (4), p.100915-100915, Article 100915

2021

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c-Jun N-Terminal Protein Kinase 1 (JNK1), but Not JNK2, Is Essential for Tumor Necrosis Factor Alpha-Induced c-Jun Kinase Activation and Apoptosis

Molecular and Cellular Biology, 2004-12, Vol.24 (24), p.10844-10856

2004

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Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006534-e1006534

2017

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BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages

eLife, 2020-12, Vol.9

2020

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Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (44), p.18886-18891

2010

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Selective Inactivation of c-Jun NH2-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

Diabetes (New York, N.Y.), 2011-02, Vol.60 (2), p.486-495

2011

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Inhibition of JNK activation through NF- κ B target genes

Nature (London), 2001-11, Vol.414 (6861), p.313-317

2001

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BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

iScience, 2021-09, Vol.24 (9), p.102942-102942, Article 102942

2021

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Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis

Cell host & microbe, 2008-10, Vol.4 (4), p.350-361

2008

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Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-α–induced JNK activation and inflammation

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (1), p.191-196

2012

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JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD

Molecular cell, 2004-02, Vol.13 (3), p.329-340

2004

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Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1

The Journal of biological chemistry, 2008-07, Vol.283 (30), p.20754-20760

2008

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Activation of NF-κB is Required for Hypertrophic Growth of Primary Rat Neonatal Ventricular Cardiomyocytes

Proceedings of the National Academy of Sciences - PNAS, 2001-06, Vol.98 (12), p.6668-6673

2001

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Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-α-induced JNK1 activation

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (43), p.18279-18284

2009

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PKCδ signaling: A dual role in regulating hypoxic stress-induced autophagy and apoptosis

Autophagy, 2009-02, Vol.5 (2), p.244-246

2009

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Cell, 1995-06, Vol.81 (7), p.1147-1157

1995

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Integration of Apoptosis Signal-Regulating Kinase 1-Mediated Stress Signaling with the Akt/Protein Kinase B-IκB Kinase Cascade

Molecular and Cellular Biology, 2013-06, Vol.33 (11), p.2252-2259

2013

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SIP30 Is Regulated by ERK in Peripheral Nerve Injury-induced Neuropathic Pain

The Journal of biological chemistry, 2009-10, Vol.284 (44), p.30138-30147

2009

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c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells

PloS one, 2012-11, Vol.7 (11), p.e48611

2012

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Activation of the JNK signaling pathway: Breaking the brake on apoptosis

Role of JNK activation in apoptosis： A double-edged sword

The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation

Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia

Multi-Omics Analysis in β-Thalassemia Using an HBB Gene-Knockout Human Erythroid Progenitor Cell Model

Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching

Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice

c-Jun N-Terminal Protein Kinase 1 (JNK1), but Not JNK2, Is Essential for Tumor Necrosis Factor Alpha-Induced c-Jun Kinase Activation and Apoptosis

Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK

BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages

Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

Selective Inactivation of c-Jun NH2-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

Inhibition of JNK activation through NF- κ B target genes

BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis

Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-α–induced JNK activation and inflammation

JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD

Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1

Activation of NF-κB is Required for Hypertrophic Growth of Primary Rat Neonatal Ventricular Cardiomyocytes

Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-α-induced JNK1 activation

PKCδ signaling: A dual role in regulating hypoxic stress-induced autophagy and apoptosis

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Integration of Apoptosis Signal-Regulating Kinase 1-Mediated Stress Signaling with the Akt/Protein Kinase B-IκB Kinase Cascade

SIP30 Is Regulated by ERK in Peripheral Nerve Injury-induced Neuropathic Pain

c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells

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