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Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

Cell, 2013-12, Vol.155 (6), p.1422-1434

2013

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Secreting and Sensing the Same Molecule Allows Cells to Achieve Versatile Social Behaviors

Science (American Association for the Advancement of Science), 2014-02, Vol.343 (6171), p.628-628

2014

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CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Cell, 2013-07, Vol.154 (2), p.442-451

2013

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Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Cell, 2013-02, Vol.152 (5), p.1173-1183

2013

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High-throughput multicolor optogenetics in microwell plates

Nature protocols, 2019-07, Vol.14 (7), p.2205-2228

2019

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Systematic Functional Prioritization of Protein Posttranslational Modifications

Cell, 2012-07, Vol.150 (2), p.413-425

2012

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Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

Science (American Association for the Advancement of Science), 2011-05, Vol.332 (6030), p.680-686

2011

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Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

Cell, 2016-02, Vol.164 (4), p.770-779

2016

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Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

Cell, 2016-02, Vol.164 (4), p.780-791

2016

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Cell-based therapeutics: the next pillar of medicine

Science translational medicine, 2013-04, Vol.5 (179), p.179ps7

2013

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CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells

Scientific reports, 2017-04, Vol.7 (1), p.737-737, Article 737

2017

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Design Principles of Regulatory Networks: Searching for the Molecular Algorithms of the Cell

Molecular cell, 2013-01, Vol.49 (2), p.202-212

2013

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Designing Synthetic Regulatory Networks Capable of Self-Organizing Cell Polarization

Cell, 2012-10, Vol.151 (2), p.320-332

2012

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Improved blue, green, and red fluorescent protein tagging vectors for S. cerevisiae

PloS one, 2013-07, Vol.8 (7), p.e67902-e67902

2013

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Oscillatory stress stimulation uncovers an Achilles' heel of the yeast MAPK signaling network

Science (American Association for the Advancement of Science), 2015-12, Vol.350 (6266), p.1379-1383

2015

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Engineering cell–cell communication networks: programming multicellular behaviors

Current opinion in chemical biology, 2019-10, Vol.52, p.31-38

2019

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Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control

Molecular cell, 2017-09, Vol.67 (5), p.757-769.e5

2017

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Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

Cell, 2015-01, Vol.160 (1-2), p.339-350

2015

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Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (40), p.16015-16020

2013

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Light-based feedback for controlling intracellular signaling dynamics

Nature methods, 2011-10, Vol.8 (10), p.837

2011

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Exploitation of Latent Allostery Enables the Evolution of New Modes of MAP Kinase Regulation

Cell, 2013-08, Vol.154 (4), p.875-887

2013

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The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

Nature methods, 2011-01, Vol.8 (1), p.35

2011

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Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

eLife, 2016-04, Vol.5

2016

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Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics

Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5869), p.1539-1543

2008

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The emerging era of cell engineering: Harnessing the modularity of cells to program complex biological function

Science (American Association for the Advancement of Science), 2022-11, Vol.378 (6622), p.848-852

Lim, Wendell A.

2022

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Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

Secreting and Sensing the Same Molecule Allows Cells to Achieve Versatile Social Behaviors

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

High-throughput multicolor optogenetics in microwell plates

Systematic Functional Prioritization of Protein Posttranslational Modifications

Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

Cell-based therapeutics: the next pillar of medicine

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells

Design Principles of Regulatory Networks: Searching for the Molecular Algorithms of the Cell

Designing Synthetic Regulatory Networks Capable of Self-Organizing Cell Polarization

Improved blue, green, and red fluorescent protein tagging vectors for S. cerevisiae

Oscillatory stress stimulation uncovers an Achilles' heel of the yeast MAPK signaling network

Engineering cell–cell communication networks: programming multicellular behaviors

Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control

Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory

Light-based feedback for controlling intracellular signaling dynamics

Exploitation of Latent Allostery Enables the Evolution of New Modes of MAP Kinase Regulation

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics

The emerging era of cell engineering: Harnessing the modularity of cells to program complex biological function

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