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PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

Clinical cancer research, 2017-07, Vol.23 (14), p.3711-3720

2017

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FBXL20‐mediated ubiquitination triggers the proteasomal degradation of 4‐1BB

The FEBS journal, 2022-08, Vol.289 (15), p.4549-4563

2022

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Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

Gut, 2019-09, Vol.68 (9), p.1653-1666

2019

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TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

The Journal of clinical investigation, 2021-04, Vol.131 (8), p.1-13

2021

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Deubiquitination and Stabilization of PD-L1 by CSN5

Cancer cell, 2016-12, Vol.30 (6), p.925-939

2016

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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Molecular cell, 2018-08, Vol.71 (4), p.606-620.e7

2018

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Saccharide analog, 2‐deoxy‐d‐glucose enhances 4‐1BB‐mediated antitumor immunity via PD‐L1 deglycosylation

Molecular carcinogenesis, 2020-07, Vol.59 (7), p.691-700

2020

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Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

Cancer cell, 2018-02, Vol.33 (2), p.187-201.e10

2018

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Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

Nature communications, 2016-08, Vol.7 (1), p.12632-11, Article 12632

2016

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IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

The Journal of clinical investigation, 2019-08, Vol.129 (8), p.3324-3338

2019

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STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion

Nature communications, 2018-05, Vol.9 (1), p.1908-17, Article 1908

2018

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EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape

Cancer research (Chicago, Ill.), 2016-03, Vol.76 (5), p.1284-1296

2016

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4-1BB: A promising target for cancer immunotherapy

Frontiers in oncology, 2022-09, Vol.12, p.968360-968360

2022

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EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

Nature (London), 2013-05, Vol.497 (7449), p.383-387

2013

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Glycosylation of Immune Receptors in Cancer

Cells (Basel, Switzerland), 2021-05, Vol.10 (5), p.1100

2021

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Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter

FEBS letters, 2010-06, Vol.584 (11), p.2427-2432

2010

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p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma

FEBS letters, 2010-06, Vol.584 (11), p.2231-2236

2010

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Oncogenic signaling pathways associated with immune evasion and resistance to immune checkpoint inhibitors in cancer

Seminars in cancer biology, 2020-10, Vol.65, p.51-64

2020

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Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

Cancer cell, 2018-04, Vol.33 (4), p.752-769.e8

2018

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Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma

Hepatology (Baltimore, Md.), 2011-04, Vol.53 (4), p.1352-1362

2011

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N -Glycosylation Facilitates 4-1BB Membrane Localization by Avoiding Its Multimerization

Cells (Basel, Switzerland), 2022-01, Vol.11 (1), p.162

2022

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Reactive oxygen species downregulate catalase expression via methylation of a CpG Island in the Oct-1 promoter

FEBS letters, 2011-11, Vol.585 (21), p.3436-3441

2011

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Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface

Proteins, structure, function, and bioinformatics, 2007-11, Vol.69 (3), p.672-678

2007

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Epigenetic Changes Induced by Reactive Oxygen Species in Hepatocellular Carcinoma: Methylation of the E-cadherin Promoter

Gastroenterology (New York, N.Y. 1943), 2008-12, Vol.135 (6), p.2128-2140.e8

2008

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Epithelial―Mesenchymal Transition Induced by TNF-α Requires NF-κB-Mediated Transcriptional Upregulation of Twist1

Cancer research (Chicago, Ill.), 2012-03, Vol.72 (5), p.1290-1300

2012

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PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

FBXL20‐mediated ubiquitination triggers the proteasomal degradation of 4‐1BB

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

Deubiquitination and Stabilization of PD-L1 by CSN5

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Saccharide analog, 2‐deoxy‐d‐glucose enhances 4‐1BB‐mediated antitumor immunity via PD‐L1 deglycosylation

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion

EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape

4-1BB: A promising target for cancer immunotherapy

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

Glycosylation of Immune Receptors in Cancer

Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter

p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma

Oncogenic signaling pathways associated with immune evasion and resistance to immune checkpoint inhibitors in cancer

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma

N -Glycosylation Facilitates 4-1BB Membrane Localization by Avoiding Its Multimerization

Reactive oxygen species downregulate catalase expression via methylation of a CpG Island in the Oct-1 promoter

Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface

Epigenetic Changes Induced by Reactive Oxygen Species in Hepatocellular Carcinoma: Methylation of the E-cadherin Promoter

Epithelial―Mesenchymal Transition Induced by TNF-α Requires NF-κB-Mediated Transcriptional Upregulation of Twist1

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