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A large fraction of HLA class I ligands are proteasome-generated spliced peptides

Science (American Association for the Advancement of Science), 2016-10, Vol.354 (6310), p.354-358

2016

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Maximizing the information content of experiments in systems biology

PLoS computational biology, 2013-01, Vol.9 (1), p.e1002888-e1002888

2013

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Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and cis -Spliced Zwitter Epitope Candidates in Type 1 Diabetes

Frontiers in immunology, 2021-04, Vol.12, p.656451

2021

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Mapping the MHC Class I-Spliced Immunopeptidome of Cancer Cells

Cancer immunology research, 2019-01, Vol.7 (1), p.62-76

2019

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Proteolytic dynamics of human 20S thymoproteasome

The Journal of biological chemistry, 2019-05, Vol.294 (19), p.7740-7754

2019

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Proteasome-Generated cis -Spliced Peptides and Their Potential Role in CD8 + T Cell Tolerance

Frontiers in immunology, 2021-02, Vol.12, p.614276-614276

2021

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Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing

Nature communications, 2024-02, Vol.15 (1), p.1147-1147, Article 1147

2024

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Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

European journal of immunology, 2014-12, Vol.44 (12), p.3508-3521

2014

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Response: Commentary: An In Silico-In Vitro Pipeline Identifying an HLA-A02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients

Frontiers in immunology, 2021-07, Vol.12, p.679836

2021

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An in silico—in vitro Pipeline Identifying an HLA-A02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients

Frontiers in immunology, 2019-11, Vol.10, p.2572-2572

2019

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Post-Translational Peptide Splicing and T Cell Responses

Trends in immunology, 2017-12, Vol.38 (12), p.904-915

2017

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Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes

Scientific data, 2020-05, Vol.7 (1), p.146-146, Article 146

2020

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GPU accelerated biochemical network simulation

Bioinformatics, 2011-03, Vol.27 (6), p.874-876

2011

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Multi-level Strategy for Identifying Proteasome-Catalyzed Spliced Epitopes Targeted by CD8+ T Cells during Bacterial Infection

Cell reports (Cambridge), 2017-08, Vol.20 (5), p.1242-1253

2017

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InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides

Scientific data, 2023-01, Vol.10 (1), p.18-22, Article 18

2023

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Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection

Stem cells (Dayton, Ohio), 2017-11, Vol.35 (11), p.2292-2304

2017

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Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes

eLife, 2015-09, Vol.4, p.e07545-e07545

2015

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The 20S proteasome splicing activity discovered by SpliceMet

PLoS computational biology, 2010-06, Vol.6 (6), p.e1000830-e1000830

2010

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An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?

Frontiers in immunology, 2017-11, Vol.8, p.1441-1441

2017

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Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?

Current opinion in immunology, 2018-06, Vol.52, p.81-86

2018

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Untangling Extracellular Proteasome-Osteopontin Circuit Dynamics in Multiple Sclerosis

Cells (Basel, Switzerland), 2019-03, Vol.8 (3), p.262

2019

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Accurate Reconstruction of Cell and Particle Tracks from 3D Live Imaging Data

Cell systems, 2016-07, Vol.3 (1), p.102-107

2016

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Proteasome isoforms in human thymi and mouse models

Immunology letters, 2024-10, Vol.269, p.106899, Article 106899

2024

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What we learned on peptide splicing in the last 2 years

Molecular immunology, 2022-10, Vol.150, p.2

2022

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inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction

Molecular & cellular proteomics, 2022-12, Vol.21 (12), p.100432-100432, Article 100432

2022

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A large fraction of HLA class I ligands are proteasome-generated spliced peptides

Maximizing the information content of experiments in systems biology

Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and cis -Spliced Zwitter Epitope Candidates in Type 1 Diabetes

Mapping the MHC Class I-Spliced Immunopeptidome of Cancer Cells

Proteolytic dynamics of human 20S thymoproteasome

Proteasome-Generated cis -Spliced Peptides and Their Potential Role in CD8 + T Cell Tolerance

Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing

Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

Response: Commentary: An In Silico-In Vitro Pipeline Identifying an HLA-A02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients

An in silico—in vitro Pipeline Identifying an HLA-A02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients

Post-Translational Peptide Splicing and T Cell Responses

Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes

GPU accelerated biochemical network simulation

Multi-level Strategy for Identifying Proteasome-Catalyzed Spliced Epitopes Targeted by CD8+ T Cells during Bacterial Infection

InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides

Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection

Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes

The 20S proteasome splicing activity discovered by SpliceMet

An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?

Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?

Untangling Extracellular Proteasome-Osteopontin Circuit Dynamics in Multiple Sclerosis

Accurate Reconstruction of Cell and Particle Tracks from 3D Live Imaging Data

Proteasome isoforms in human thymi and mouse models

What we learned on peptide splicing in the last 2 years

inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction

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