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Prediction of rho-independent transcriptional terminators in Escherichia coli

Nucleic acids research, 2001-09, Vol.29 (17), p.3583-3594

2001

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Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression

The Journal of biological chemistry, 1993-07, Vol.268 (19), p.14514-14522

1993

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Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexes

Biochemical journal, 1995-12, Vol.312 ( Pt 2) (2), p.599-608

1995

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Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Journal of medicinal chemistry, 1993-04, Vol.36 (7), p.831-841

1993

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Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats

The Journal of pharmacology and experimental therapeutics, 2001-03, Vol.296 (3), p.890

2001

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Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Biochemistry (Easton), 1993-08, Vol.32 (30), p.7832-7838

1993

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Biophysical and antisense properties of oligodeoxynucleotides containing 7-propynyl-, 7-iodo- and 7-cyano-7-deaza-2-amino-2'-deoxyadenosines

Nucleic acids research, 1998-07, Vol.26 (14), p.3350-3357

1998

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Relative Thermodynamic Stability of DNA, RNA, and DNA:RNA Hybrid Duplexes: Relationship with Base Composition and Structure

Biochemistry (Easton), 1995-08, Vol.34 (34), p.10807-10815

1995

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2'-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells

The Journal of biological chemistry, 1997-05, Vol.272 (18), p.11994-12000

1997

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Tritium labeling of antisense oligonucleotides by exchange with tritiated water

Nucleic acids research, 1993-08, Vol.21 (16), p.3737-3743

1993

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2‘-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2‘-O-[2-(Methoxy)-ethyl]-Modified Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA

Biochemistry (Easton), 2002-10, Vol.41 (39), p.11642-11648

2002

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Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (26), p.15481-15484

1996

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What Affects the Effect of 2‘-Alkoxy Modifications? 1. Stabilization Effect of 2‘-Methoxy Substitutions in Uniformly Modified DNA Oligonucleotides

Biochemistry (Easton), 1998-05, Vol.37 (19), p.6991-6997

1998

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Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

Nucleic acids research, 1995-06, Vol.23 (11), p.2019-2024

1995

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The inhibition of restriction endonucleases due to Z-DNA in negatively supercoiled plasmid

FEBS letters, 1991-03, Vol.280 (1), p.91-93

1991

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Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications

Nucleic acids research, 1996-02, Vol.24 (3), p.411-417

1996

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Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2‘-O-Ribonucleic Acid Modifications

Biochemistry (Easton), 2005-06, Vol.44 (25), p.9045-9057

2005

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Investigation of some properties of oligodeoxynucleotides containing 4'-thio-2'-deoxynucleotides: duplex hybridization and nuclease sensitivity

Nucleic acids research, 1996-11, Vol.24 (21), p.4117-4122

1996

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Evaluation of pyrimidine PNA binding to ssDNA targets from nonequilibrium melting experiments

Nucleic acids research, 1997-02, Vol.25 (3), p.568-574

1997

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A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome

BioSystems, 2002-03, Vol.65 (2), p.157-177

2002

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High-Affinity Peptide Nucleic Acid Oligomers Containing Tricyclic Cytosine Analogues

Organic letters, 2002-12, Vol.4 (25), p.4395-4398

2002

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2‘-O-[2-(Amino)-2-oxoethyl] Oligonucleotides

Organic letters, 2003-02, Vol.5 (4), p.403-406

2003

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Studies on the effect of conformation on the rate of the slow isotope hydrogen exchange in polyadenylic acid

Biochemical and biophysical research communications, 1969-02, Vol.34 (3), p.260-265

1969

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Synthesis of 2′- O-[2-[( N, N-dialkylamino)oxy]ethyl]-modified oligonucleotides: hybridization affinity, resistance to nuclease, and protein binding characteristics

Tetrahedron, 2003-09, Vol.59 (37), p.7413-7422

2003

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Single and Bis Peptide Nucleic Acids as Triplexing Agents: Binding and Stoichiometry

Journal of the American Chemical Society, 1995, Vol.117 (2), p.831-832

1995

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Prediction of rho-independent transcriptional terminators in Escherichia coli

Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression

Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexes

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Biophysical and antisense properties of oligodeoxynucleotides containing 7-propynyl-, 7-iodo- and 7-cyano-7-deaza-2-amino-2'-deoxyadenosines

Relative Thermodynamic Stability of DNA, RNA, and DNA:RNA Hybrid Duplexes: Relationship with Base Composition and Structure

2'-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells

Tritium labeling of antisense oligonucleotides by exchange with tritiated water

2‘-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2‘-O-[2-(Methoxy)-ethyl]-Modified Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA

Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo

What Affects the Effect of 2‘-Alkoxy Modifications? 1. Stabilization Effect of 2‘-Methoxy Substitutions in Uniformly Modified DNA Oligonucleotides

Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

The inhibition of restriction endonucleases due to Z-DNA in negatively supercoiled plasmid

Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications

Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2‘-O-Ribonucleic Acid Modifications

Investigation of some properties of oligodeoxynucleotides containing 4'-thio-2'-deoxynucleotides: duplex hybridization and nuclease sensitivity

Evaluation of pyrimidine PNA binding to ssDNA targets from nonequilibrium melting experiments

A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome

High-Affinity Peptide Nucleic Acid Oligomers Containing Tricyclic Cytosine Analogues

2‘-O-[2-(Amino)-2-oxoethyl] Oligonucleotides

Studies on the effect of conformation on the rate of the slow isotope hydrogen exchange in polyadenylic acid

Synthesis of 2′- O-[2-[( N, N-dialkylamino)oxy]ethyl]-modified oligonucleotides: hybridization affinity, resistance to nuclease, and protein binding characteristics

Single and Bis Peptide Nucleic Acids as Triplexing Agents: Binding and Stoichiometry

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