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mechanisms of alloxan- and streptozotocin-induced diabetes

Diabetologia, 2008-02, Vol.51 (2), p.216-226

Lenzen, S

2008

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Role of metabolically generated reactive oxygen species for lipotoxicity in pancreatic β-cells

Diabetes, obesity & metabolism, 2010-10, Vol.12 (s2), p.149-158

2010

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Structure-toxicity relationships of saturated and unsaturated free fatty acids for elucidating the lipotoxic effects in human EndoC-βH1 beta-cells

Biochimica et biophysica acta. Molecular basis of disease, 2019-11, Vol.1865 (11), p.165525, Article 165525

2019

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Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

Diabetologia, 2010-06, Vol.53 (6), p.1120-1130

2010

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Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets

Diabetologia, 2013-04, Vol.56 (4), p.774-782

2013

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N-glycosylation-negative catalase: a useful tool for exploring the role of hydrogen peroxide in the endoplasmic reticulum

Free radical biology & medicine, 2015-03, Vol.80, p.77-83

2015

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Effect of substrate rigidity in tissue culture on the function of insulin‐secreting INS‐1E cells

Journal of tissue engineering and regenerative medicine, 2017-01, Vol.11 (1), p.58-65

2017

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Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin

Diabetologia, 2000-12, Vol.43 (12), p.1528-1533

2000

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Impact of scavenging hydrogen peroxide in the endoplasmic reticulum for β cell function

Journal of molecular endocrinology, 2015-08, Vol.55 (1), p.21-29

2015

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Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan

Diabetologia, 2002-11, Vol.45 (11), p.1542-1549

2002

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Progesterone induces apoptosis of insulin-secreting cells: insights into the molecular mechanism

Journal of endocrinology, 2014-05, Vol.221 (2), p.273-284

2014

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Glucokinase mediates coupling of glycolysis to mitochondrial metabolism but not to beta cell damage at high glucose exposure levels

Diabetologia, 2011-07, Vol.54 (7), p.1744-1755

2011

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Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines

Diabetologia, 2005-08, Vol.48 (8), p.1541-1548

2005

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Influence of cytokines on Dmt1 iron transporter and ferritin expression in insulin-secreting cells

Journal of molecular endocrinology, 2014-06, Vol.52 (3), p.301-310

2014

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Monitoring of glucose-regulated single insulin secretory granule movement by selective photoactivation

Diabetologia, 2008-06, Vol.51 (6), p.989-996

2008

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Variable immune cell frequencies in peripheral blood of LEW.1AR1‐iddm rats over time compared to other congenic LEW strains

Clinical and experimental immunology, 2014-07, Vol.177 (1), p.168-178

2014

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Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes

Diabetes (New York, N.Y.), 2000-07, Vol.49 (7), p.1123-1130

2000

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Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species

Diabetes (New York, N.Y.), 1998-10, Vol.47 (10), p.1578

1998

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Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells

Diabetologia, 1999-07, Vol.42 (7), p.849-855

1999

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Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan

Journal of endocrinology, 2012-08, Vol.214 (2), p.233-238

2012

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Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan

Journal of endocrinology, 2012-09, Vol.214 (3), p.445-446

2012

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An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells

Cell proliferation, 2008-08, Vol.41 (4), p.607-624

2008

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Diabetes therapy by lentiviral hepatic insulin gene expression without transformation of liver

Diabetologia, 2008-04, Vol.51 (4), p.694-695

2008

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The LEW.1AR1/Ztm-iddm rat : a new model of spontaneous insulin-dependent diabetes mellitus

Diabetologia, 2001-09, Vol.44 (9), p.1189-1196

2001

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Mechanism underlying resistance of human pancreatic beta cells against toxicity of streptozotocin and alloxan

Diabetologia, 2003-12, Vol.46 (12), p.1713-1714

2003

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mechanisms of alloxan- and streptozotocin-induced diabetes

Role of metabolically generated reactive oxygen species for lipotoxicity in pancreatic β-cells

Structure-toxicity relationships of saturated and unsaturated free fatty acids for elucidating the lipotoxic effects in human EndoC-βH1 beta-cells

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets

N-glycosylation-negative catalase: a useful tool for exploring the role of hydrogen peroxide in the endoplasmic reticulum

Effect of substrate rigidity in tissue culture on the function of insulin‐secreting INS‐1E cells

Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin

Impact of scavenging hydrogen peroxide in the endoplasmic reticulum for β cell function

Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan

Progesterone induces apoptosis of insulin-secreting cells: insights into the molecular mechanism

Glucokinase mediates coupling of glycolysis to mitochondrial metabolism but not to beta cell damage at high glucose exposure levels

Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines

Influence of cytokines on Dmt1 iron transporter and ferritin expression in insulin-secreting cells

Monitoring of glucose-regulated single insulin secretory granule movement by selective photoactivation

Variable immune cell frequencies in peripheral blood of LEW.1AR1‐iddm rats over time compared to other congenic LEW strains

Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes

Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species

Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells

Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan

Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan

An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells

Diabetes therapy by lentiviral hepatic insulin gene expression without transformation of liver

The LEW.1AR1/Ztm-iddm rat : a new model of spontaneous insulin-dependent diabetes mellitus

Mechanism underlying resistance of human pancreatic beta cells against toxicity of streptozotocin and alloxan

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