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Intestinal permeability and its relevance for absorption and elimination

Xenobiotica, 2007-11, Vol.37 (10-11), p.1015-1051

Lennernaes, H

2007

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Intestinal absorption-modifying excipients: A current update on preclinical in vivo evaluations

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.411-420

2019

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Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport

International journal of pharmaceutics, 2018-10, Vol.549 (1-2), p.239-248

2018

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The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs

International journal of pharmaceutics, 2018-08, Vol.547 (1-2), p.158-168

2018

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Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability

European journal of pharmaceutics and biopharmaceutics, 2021-06, Vol.163, p.240-251

2021

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Levodopa infusion combined with entacapone or tolcapone in Parkinson disease: a pilot trial

European journal of neurology, 2012-06, Vol.19 (6), p.820-826

2012

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Improved Cortisol Exposure-Time Profile and Outcome in Patients with Adrenal Insufficiency: A Prospective Randomized Trial of a Novel Hydrocortisone Dual-Release Formulation

The journal of clinical endocrinology and metabolism, 2012-02, Vol.97 (2), p.473-481

2012

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Mechanistic modelling of intestinal drug absorption – The in vivo effects of nanoparticles, hydrodynamics, and colloidal structures

European journal of pharmaceutics and biopharmaceutics, 2018-12, Vol.133, p.70-76

2018

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Single bead investigation of a clinical drug delivery system – A novel release mechanism

Journal of controlled release, 2018-12, Vol.292, p.235-247

2018

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Rat intestinal drug permeability: A status report and summary of repeated determinations

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.364-376

2019

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A miniaturized in vitro release method for investigating drug-release mechanisms

International journal of pharmaceutics, 2015, Vol.486 (1-2), p.339-349

2015

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Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain

British journal of clinical pharmacology, 2005-02, Vol.59 (2), p.249-253

2005

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Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.31-37

2019

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Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer

European journal of pharmaceutics and biopharmaceutics, 2018-11, Vol.132, p.222-230

2018

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Six years of progress in the oral biopharmaceutics area – A summary from the IMI OrBiTo project

European journal of pharmaceutics and biopharmaceutics, 2020-07, Vol.152, p.236-247

2020

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The progression of doxorubicin-induced intestinal mucositis in rats

Naunyn-Schmiedeberg's archives of pharmacology, 2023-02, Vol.396 (2), p.247-260

2023

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Time-dependent effects on small intestinal transport by absorption-modifying excipients

European journal of pharmaceutics and biopharmaceutics, 2018-11, Vol.132, p.19-28

2018

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Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.387-395

2019

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Computational fluid dynamics (CFD) studies of a miniaturized dissolution system

International journal of pharmaceutics, 2017-04, Vol.521 (1-2), p.274-281

2017

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Assessment of enzymatic prodrug stability in human, dog and simulated intestinal fluids

European journal of pharmaceutics and biopharmaceutics, 2012-04, Vol.80 (3), p.630-637

2012

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Prospective evaluation of long-term safety of dual-release hydrocortisone replacement administered once daily in patients with adrenal insufficiency

European journal of endocrinology, 2014-09, Vol.171 (3), p.369-377

2014

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Human Intestinal Permeability

Journal of pharmaceutical sciences, 1998-04, Vol.87 (4), p.403-410

LENNERNIS, H

1998

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Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors : Similarities and differences

Clinical pharmacokinetics, 1997-05, Vol.32 (5), p.403-425

1997

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In vitro and in vivo evaluation of a new sublingual tablet system for rapid oromucosal absorption using fentanyl citrate as the active substance

European journal of pharmaceutical sciences, 2003-11, Vol.20 (3), p.327-334

2003

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Bioequivalence of Oral Products and the Biopharmaceutics Classification System: Science, Regulation, and Public Policy

Clinical pharmacology and therapeutics, 2011-09, Vol.90 (3), p.467-470

2011

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Intestinal permeability and its relevance for absorption and elimination

Intestinal absorption-modifying excipients: A current update on preclinical in vivo evaluations

Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport

The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs

Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability

Levodopa infusion combined with entacapone or tolcapone in Parkinson disease: a pilot trial

Improved Cortisol Exposure-Time Profile and Outcome in Patients with Adrenal Insufficiency: A Prospective Randomized Trial of a Novel Hydrocortisone Dual-Release Formulation

Mechanistic modelling of intestinal drug absorption – The in vivo effects of nanoparticles, hydrodynamics, and colloidal structures

Single bead investigation of a clinical drug delivery system – A novel release mechanism

Rat intestinal drug permeability: A status report and summary of repeated determinations

A miniaturized in vitro release method for investigating drug-release mechanisms

Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain

Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model

Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer

Six years of progress in the oral biopharmaceutics area – A summary from the IMI OrBiTo project

The progression of doxorubicin-induced intestinal mucositis in rats

Time-dependent effects on small intestinal transport by absorption-modifying excipients

Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions

Computational fluid dynamics (CFD) studies of a miniaturized dissolution system

Assessment of enzymatic prodrug stability in human, dog and simulated intestinal fluids

Prospective evaluation of long-term safety of dual-release hydrocortisone replacement administered once daily in patients with adrenal insufficiency

Human Intestinal Permeability

Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors : Similarities and differences

In vitro and in vivo evaluation of a new sublingual tablet system for rapid oromucosal absorption using fentanyl citrate as the active substance

Bioequivalence of Oral Products and the Biopharmaceutics Classification System: Science, Regulation, and Public Policy

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