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Colorectal Tumors Responding to 5-Fluorouracil Have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase, and Thymidine Phosphorylase

Clinical cancer research, 2000-04, Vol.6 (4), p.1322-1327

2000

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Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin

Journal of clinical oncology, 1997-10, Vol.15 (10), p.3223-3229

1997

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High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil

Clinical cancer research, 1998-10, Vol.4 (10), p.2371-2376

1998

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Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival

Journal of clinical oncology, 1996-01, Vol.14 (1), p.176-182

1996

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p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival

Clinical cancer research, 1998-05, Vol.4 (5), p.1243-1250

1998

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p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site

Clinical cancer research, 1998-05, Vol.4 (5), p.1227-1234

1998

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ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy

Journal of clinical oncology, 1998-01, Vol.16 (1), p.309-316

1998

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A phase I and pharmacokinetic study of irinotecan in patients with hepatic or renal dysfunction or with prior pelvic radiation: CALGB 9863

Annals of oncology, 2003-12, Vol.14 (12), p.1783-1790

2003

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Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors

Cancer research (Chicago, Ill.), 1995-04, Vol.55 (7), p.1407-1412

1995

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Phase II study of fluorouracil and its modulation in advanced colorectal cancer: a Southwest Oncology Group study

Journal of clinical oncology, 1995-06, Vol.13 (6), p.1303-1311

1995

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Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer

Cancer chemotherapy and pharmacology, 2015, Vol.75 (1), p.17-23

2015

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Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy : A final report

Cancer, 1997-05, Vol.79 (9), p.1767-1775

1997

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Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program

Journal of clinical oncology, 1992-12, Vol.10 (12), p.1933-1942

1992

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Erratum to: Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer

Cancer chemotherapy and pharmacology, 2015, Vol.75 (1), p.25-25

2015

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Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial

European journal of cancer (1990), 1995-07, Vol.31 (7), p.1306-1310

1995

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Expression of Genes Related to Activity of Oxaliplatin and 5-Fluorouracil in Endoscopic Biopsies of Primary Esophageal Cancer in Patients Receiving Oxaliplatin, 5-Flourouracil and Radiation: Characterization and Exploratory Analysis with Survival

Journal of chemotherapy (Florence), 2006-10, Vol.18 (5), p.514-524

2006

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A fixed‐ratio combination of uracil and ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer

Cancer, 1995-02, Vol.75 (3), p.782-785

1995

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Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil

Clinical cancer research, 1996-09, Vol.2 (9), p.1461-1467

1996

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Phase I Study of (6R)-5, 10-Dideazatetrahydrofolate: a Folate Antimetabolite Inhibitory to De Novo Purine Synthesis

JNCI : Journal of the National Cancer Institute, 1993-07, Vol.85 (14), p.1154-1159

1993

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Prolonged Continuous Infusion of Fluorouracil With Weekly Bolus Leucovorin: A Phase II Study in Patients With Disseminated Colorectal Cancer

JNCI : Journal of the National Cancer Institute, 1993-01, Vol.85 (1), p.41-44

1993

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Nonoperative therapy for squamous-cell cancer of the esophagus

Journal of clinical oncology, 1987-03, Vol.5 (3), p.365-370

1987

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Therapy of disseminated colorectal cancer: the emerging role of intratumoral molecular biology

The European journal of surgery, 2001-08, Vol.167 (S8), p.43-48

2001

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Predictive and prognostic markers in gastrointestinal cancers

Current opinion in oncology, 2001-07, Vol.13 (4), p.291-299

Leichman, Cynthia Gail

2001

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Sustained Ventricular Tachycardia and Its Successful Prophylaxis During High-Dose Bolus Interleukin-2 Therapy for Metastatic Renal Cell Carcinoma

American journal of clinical oncology, 2000-02, Vol.23 (1), p.34-36, Article 34

2000

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Hepatic chemoembolization combined with systemic infusion of 5-fluorouracil and bolus leucovorin for patients with metastatic colorectal carcinoma : A Southwest Oncology Group pilot trial

Cancer, 1999-09, Vol.86 (5), p.775-781

1999

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Colorectal Tumors Responding to 5-Fluorouracil Have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase, and Thymidine Phosphorylase

Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin

High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil

Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival

p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival

p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site

ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy

A phase I and pharmacokinetic study of irinotecan in patients with hepatic or renal dysfunction or with prior pelvic radiation: CALGB 9863

Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors

Phase II study of fluorouracil and its modulation in advanced colorectal cancer: a Southwest Oncology Group study

Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer

Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy : A final report

Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program

Erratum to: Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer

Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial

Expression of Genes Related to Activity of Oxaliplatin and 5-Fluorouracil in Endoscopic Biopsies of Primary Esophageal Cancer in Patients Receiving Oxaliplatin, 5-Flourouracil and Radiation: Characterization and Exploratory Analysis with Survival

A fixed‐ratio combination of uracil and ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer

Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil

Phase I Study of (6R)-5, 10-Dideazatetrahydrofolate: a Folate Antimetabolite Inhibitory to De Novo Purine Synthesis

Prolonged Continuous Infusion of Fluorouracil With Weekly Bolus Leucovorin: A Phase II Study in Patients With Disseminated Colorectal Cancer

Nonoperative therapy for squamous-cell cancer of the esophagus

Therapy of disseminated colorectal cancer: the emerging role of intratumoral molecular biology

Predictive and prognostic markers in gastrointestinal cancers

Sustained Ventricular Tachycardia and Its Successful Prophylaxis During High-Dose Bolus Interleukin-2 Therapy for Metastatic Renal Cell Carcinoma

Hepatic chemoembolization combined with systemic infusion of 5-fluorouracil and bolus leucovorin for patients with metastatic colorectal carcinoma : A Southwest Oncology Group pilot trial

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