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Local and Systemic Immunity against Respiratory Syncytial Virus Induced by a Novel Intranasal Vaccine. A Randomized, Double-Blind, Placebo-controlled Clinical Trial

American journal of respiratory and critical care medicine, 2019-08, Vol.200 (4), p.481-492

2019

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Exploiting the peptidoglycan-binding motif, LysM, for medical and industrial applications

Applied microbiology and biotechnology, 2014-05, Vol.98 (10), p.4331-4345

2014

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A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles

PloS one, 2013-08, Vol.8 (8), p.e71072

2013

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Cell Wall Attachment of a Widely Distributed Peptidoglycan Binding Domain Is Hindered by Cell Wall Constituents

The Journal of biological chemistry, 2003-06, Vol.278 (26), p.23874-23881

2003

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Shigella IpaB and IpaD displayed on L. lactis bacterium‐like particles induce protective immunity in adult and infant mice

Immunology and cell biology, 2015-08, Vol.93 (7), p.641-652

2015

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AcmD, a homolog of the major autolysin AcmA of Lactococcus lactis, binds to the cell wall and contributes to cell separation and autolysis

PloS one, 2013-08, Vol.8 (8), p.e72167-e72167

2013

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Lantibiotic Structures as Guidelines for the Design of Peptides That Can Be Modified by Lantibiotic Enzymes

Biochemistry (Easton), 2005-06, Vol.44 (24), p.8873-8882

2005

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Novel Surface Display System for Proteins on Non-Genetically Modified Gram-Positive Bacteria

Applied and Environmental Microbiology, 2006-01, Vol.72 (1), p.880-889

2006

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Bacterium-like particles as multi-epitope delivery platform for Plasmodium berghei circumsporozoite protein induce complete protection against malaria in mice

Malaria journal, 2012-02, Vol.11 (1), p.50-50, Article 50

2012

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NisT, the Transporter of the Lantibiotic Nisin, Can Transport Fully Modified, Dehydrated, and Unmodified Prenisin and Fusions of the Leader Peptide with Non-lantibiotic Peptides

The Journal of biological chemistry, 2004-05, Vol.279 (21), p.22176-22182

2004

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Detection and Localization of Single LysM-Peptidoglycan Interactions

Journal of Bacteriology, 2008-11, Vol.190 (21), p.7079-7086

2008

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Mucosal vaccine delivery of antigens tightly bound to an adjuvant particle made from food-grade bacteria

Methods (San Diego, Calif.), 2006-02, Vol.38 (2), p.144-149

2006

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Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics

PloS one, 2015-06, Vol.10 (6), p.e0130829-e0130829

2015

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Lactococcus lactis GEM particles displaying pneumococcal antigens induce local and systemic immune responses following intranasal immunization

Vaccine, 2006-06, Vol.24 (26), p.5434-5441

2006

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Development of lactococcal GEM-based pneumococcal vaccines

Vaccine, 2007-03, Vol.25 (13), p.2497-2506

2007

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chloride-inducible acid resistance mechanism in Lactococcus lactis and its regulation

Molecular microbiology, 1998-01, Vol.27 (2), p.299-310

1998

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Anchoring of proteins to lactic acid bacteria

Antonie van Leeuwenhoek, 1999-11, Vol.76 (1-4), p.367-376

1999

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Lactococcus lactis‐derived microparticles ad mixed with allergen shift immune responses towards a regulatory profile in tree‐nut allergic patients

Allergy (Copenhagen), 2023-03, Vol.78 (3), p.851-855

2023

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Cre-loxP Recombination System for Large Genome Rearrangements in Lactococcus lactis

Applied and Environmental Microbiology, 2002-05, Vol.68 (5), p.2359-2367

2002

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Safety, reactogenicity and immunogenicity of an intranasal seasonal influenza vaccine adjuvanted with gram-positive matrix (GEM) particles (FluGEM): A randomized, double-blind, controlled, ascending dose study in healthy adults and elderly

Vaccine, 2024-09, Vol.42 (22), p.125836, Article 125836

2024

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Characterization of Epitope-Specific Anti-Respiratory Syncytial Virus (Anti-RSV) Antibody Responses after Natural Infection and after Vaccination with Formalin-Inactivated RSV

Journal of virology, 2016-07, Vol.90 (13), p.5965-5977

2016

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Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk

Journal of Bacteriology, 1996-05, Vol.178 (10), p.2794-2803

1996

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Bacterium-like particles for efficient immune stimulation of existing vaccines and new subunit vaccines in mucosal applications

Frontiers in immunology, 2013, Vol.4, p.282-282

2013

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Bacterium-like particles supplemented with inactivated influenza antigen induce cross-protective influenza-specific antibody responses through intranasal administration

Vaccine, 2012-07, Vol.30 (32), p.4884-4891

2012

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Short‐course sublingual immunotherapy by mucoadhesive patch and tolerogenic particle enhanced allergen presentation

Clinical and experimental allergy, 2021-06, Vol.51 (6), p.853-857

2021

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Local and Systemic Immunity against Respiratory Syncytial Virus Induced by a Novel Intranasal Vaccine. A Randomized, Double-Blind, Placebo-controlled Clinical Trial

Exploiting the peptidoglycan-binding motif, LysM, for medical and industrial applications

A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles

Cell Wall Attachment of a Widely Distributed Peptidoglycan Binding Domain Is Hindered by Cell Wall Constituents

Shigella IpaB and IpaD displayed on L. lactis bacterium‐like particles induce protective immunity in adult and infant mice

AcmD, a homolog of the major autolysin AcmA of Lactococcus lactis, binds to the cell wall and contributes to cell separation and autolysis

Lantibiotic Structures as Guidelines for the Design of Peptides That Can Be Modified by Lantibiotic Enzymes

Novel Surface Display System for Proteins on Non-Genetically Modified Gram-Positive Bacteria

Bacterium-like particles as multi-epitope delivery platform for Plasmodium berghei circumsporozoite protein induce complete protection against malaria in mice

NisT, the Transporter of the Lantibiotic Nisin, Can Transport Fully Modified, Dehydrated, and Unmodified Prenisin and Fusions of the Leader Peptide with Non-lantibiotic Peptides

Detection and Localization of Single LysM-Peptidoglycan Interactions

Mucosal vaccine delivery of antigens tightly bound to an adjuvant particle made from food-grade bacteria

Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics

Lactococcus lactis GEM particles displaying pneumococcal antigens induce local and systemic immune responses following intranasal immunization

Development of lactococcal GEM-based pneumococcal vaccines

chloride-inducible acid resistance mechanism in Lactococcus lactis and its regulation

Anchoring of proteins to lactic acid bacteria

Lactococcus lactis‐derived microparticles ad mixed with allergen shift immune responses towards a regulatory profile in tree‐nut allergic patients

Cre-loxP Recombination System for Large Genome Rearrangements in Lactococcus lactis

Safety, reactogenicity and immunogenicity of an intranasal seasonal influenza vaccine adjuvanted with gram-positive matrix (GEM) particles (FluGEM): A randomized, double-blind, controlled, ascending dose study in healthy adults and elderly

Characterization of Epitope-Specific Anti-Respiratory Syncytial Virus (Anti-RSV) Antibody Responses after Natural Infection and after Vaccination with Formalin-Inactivated RSV

Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk

Bacterium-like particles for efficient immune stimulation of existing vaccines and new subunit vaccines in mucosal applications

Bacterium-like particles supplemented with inactivated influenza antigen induce cross-protective influenza-specific antibody responses through intranasal administration

Short‐course sublingual immunotherapy by mucoadhesive patch and tolerogenic particle enhanced allergen presentation

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