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Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system

Mechanisms of ageing and development, 1989, Vol.48 (2), p.145-155

1989

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The Physiologic, Neurologic, and Behavioral Effects of Caloric Restriction Related to Aging, Disease, and Environmental Factors

Environmental research, 1997-01, Vol.73 (1-2), p.242-248

1997

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Adaptive role of caloric intake on the degenerative disease processes

Toxicological sciences, 1999-12, Vol.52 (2), p.3-12

1999

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The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microsomes

Molecular pharmacology, 1988-12, Vol.34 (6), p.729-735

1988

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An improved assay technique for uridine diphosphate glucuronosyltransferase activity towards 5-hydroxytryptamine and some properties of the enzyme

Biochemical journal, 1978-12, Vol.175 (3), p.1119-1124

Leakey, J E

1978

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Development of multiple activities of UDP-glucuronyltransferase in human liver

Biochemical journal, 1987-05, Vol.243 (3), p.859-861

1987

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Dietary restriction in humans: report on the Little Rock Conference on the value, feasibility, and parameters of a proposed study

Mechanisms of ageing and development, 1996-10, Vol.91 (2), p.79-94

1996

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Phase I and phase II enzymes produced by Cunninghamella elegans for the metabolism of xenobiotics

FEMS microbiology letters, 1996-05, Vol.138 (2/3), p.221-226

1996

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The effect of propylene glycol on the P450-dependent metabolism of acetaminophen and other chemicals in subcellular fractions of mouse liver

Life sciences (1973), 1993, Vol.52 (2), p.183-189

1993

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A mechanistic basis for the beneficial effects of caloric restriction on longevity and disease : Consequences for the interpretation of rodent toxicity studies: Symposium: nutrition and toxicity modulation: the impact of animal body weight on study outcome

International journal of toxicology, 1998, Vol.17, p.5-56

1998

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Development of the rat hepatic microsomal glucose-6-phosphatase system and its glucocorticoid inducibility

Biology of the neonate, 1988, Vol.54 (2), p.107-115

1988

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The effect of aging and dietary restriction on the retinoylation of nuclear matrix proteins in rats

Aging (Milan, Italy), 1996-08, Vol.8 (4), p.263-270

1996

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P48: a novel nuclear protein possibly associated with aging and mortality

Aging (Milan, Italy), 1996-10, Vol.8 (5), p.311-319

1996

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Susceptibility to phenobarbital promotion of hepatotumorigenesis : correlation with differential expression and induction of hepatic drug metabolizing enzymes in heavy and light male (C3H × VY) F1 hybrid mice

Carcinogenesis (New York), 1991-05, Vol.12 (5), p.911-915

1991

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Synthesis and stability of isotopically labeled p-chloro-m-xylenol (PCMX)

Pharmaceutical research, 1993-10, Vol.10 (10), p.1466-1470

1993

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Precocious development of cytochrome P-450 in neonatal rat liver after glucocorticoid treatment

Biochemical journal, 1979-07, Vol.182 (1), p.233-235

1979

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Dexamethasone induces hepatic cytochrome P-450 content and increases certain monooxygenase activities in rhesus monkey fetuses

Biochemical pharmacology, 1986-04, Vol.35 (8), p.1389-1391

1986

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Dexamethasone increases UDP-glucuronyltransferase activity towards bilirubin, oestradiol and testosterone in foetal liver from rhesus monkey during late gestation

Biochemical journal, 1985-01, Vol.225 (1), p.183-188

1985

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UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys

Biochemical journal, 1983-09, Vol.214 (3), p.1007-1009

1983

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Human cytochrome P450IIA3 : cDNA sequence, role of the enzyme in the metabolic activation of promutagen, comparison to nitrosamine activation by human cytochrome P450IIE1

Carcinogenesis (New York), 1990, Vol.11 (8), p.1293-1300

1990

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Precocious development of uridine diphosphate glucuronosyltransferase activity during organ culture of foetal rat liver in the presence of glucocorticoids

Biochemical journal, 1977-08, Vol.166 (2), p.249-253

1977

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Differential stability of drug-metabolizing enzyme activities in primary rat hepatocytes, cultured in the absence or presence of dexamethasone

Mutation research, 1991-07, Vol.249 (1), p.81-92

1991

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The high mobility group of nuclear proteins as biomarkers of age and caloric restriction in rats

Biochemistry international, 1992-04, Vol.26 (5), p.953

1992

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Contributions — A: General Session

Carcinogenic and Anticarcinogenic Factors in Food, 2000, p.15-100

2000

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Subchronic toxicity evaluation of glucosamine and glucosamine in combination with chondroitin sulfate in obese Zucker rats

Toxicology and applied pharmacology, 2021-02, Vol.412, p.115371, Article 115371

2021

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Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system

The Physiologic, Neurologic, and Behavioral Effects of Caloric Restriction Related to Aging, Disease, and Environmental Factors

Adaptive role of caloric intake on the degenerative disease processes

The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microsomes

An improved assay technique for uridine diphosphate glucuronosyltransferase activity towards 5-hydroxytryptamine and some properties of the enzyme

Development of multiple activities of UDP-glucuronyltransferase in human liver

Dietary restriction in humans: report on the Little Rock Conference on the value, feasibility, and parameters of a proposed study

Phase I and phase II enzymes produced by Cunninghamella elegans for the metabolism of xenobiotics

The effect of propylene glycol on the P450-dependent metabolism of acetaminophen and other chemicals in subcellular fractions of mouse liver

A mechanistic basis for the beneficial effects of caloric restriction on longevity and disease : Consequences for the interpretation of rodent toxicity studies: Symposium: nutrition and toxicity modulation: the impact of animal body weight on study outcome

Development of the rat hepatic microsomal glucose-6-phosphatase system and its glucocorticoid inducibility

The effect of aging and dietary restriction on the retinoylation of nuclear matrix proteins in rats

P48: a novel nuclear protein possibly associated with aging and mortality

Susceptibility to phenobarbital promotion of hepatotumorigenesis : correlation with differential expression and induction of hepatic drug metabolizing enzymes in heavy and light male (C3H × VY) F1 hybrid mice

Synthesis and stability of isotopically labeled p-chloro-m-xylenol (PCMX)

Precocious development of cytochrome P-450 in neonatal rat liver after glucocorticoid treatment

Dexamethasone induces hepatic cytochrome P-450 content and increases certain monooxygenase activities in rhesus monkey fetuses

Dexamethasone increases UDP-glucuronyltransferase activity towards bilirubin, oestradiol and testosterone in foetal liver from rhesus monkey during late gestation

UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys

Human cytochrome P450IIA3 : cDNA sequence, role of the enzyme in the metabolic activation of promutagen, comparison to nitrosamine activation by human cytochrome P450IIE1

Precocious development of uridine diphosphate glucuronosyltransferase activity during organ culture of foetal rat liver in the presence of glucocorticoids

Differential stability of drug-metabolizing enzyme activities in primary rat hepatocytes, cultured in the absence or presence of dexamethasone

The high mobility group of nuclear proteins as biomarkers of age and caloric restriction in rats

Contributions — A: General Session

Subchronic toxicity evaluation of glucosamine and glucosamine in combination with chondroitin sulfate in obese Zucker rats

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