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Cell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process

Current opinion in biotechnology, 2016-08, Vol.40, p.185-192

2016

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A computational modeling approach for predicting multicell spheroid patterns based on signaling-induced differential adhesion

PLoS computational biology, 2022-11, Vol.18 (11), p.e1010701-e1010701

2022

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Correction: A computational modeling approach for predicting multicell spheroid patterns based on signaling-induced differential adhesion

PLoS computational biology, 2023-05, Vol.19 (5), p.e1011166-e1011166

2023

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Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling

Cell reports (Cambridge), 2020-03, Vol.30 (10), p.3383-3396.e7

2020

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Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

eLife, 2020-04, Vol.9

2020

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Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors

Cancer discovery, 2012-10, Vol.2 (10), p.934-947

2012

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p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (32), p.E3287-E3296

2014

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Computational Analysis of the Regulation of EGFR by Protein Tyrosine Phosphatases

Biophysical journal, 2012-05, Vol.102 (9), p.2012-2021

2012

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EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR

Science signaling, 2015-05, Vol.8 (376), p.ra46

2015

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CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer

Cancers, 2021-10, Vol.13 (20), p.5056

2021

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ERK1/2 Blockade Prevents Epithelial―Mesenchymal Transition in Lung Cancer Cells and Promotes Their Sensitivity to EGFR Inhibition

Cancer research (Chicago, Ill.), 2014-01, Vol.74 (1), p.309-319

2014

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Structural determinants of glomerular permeability

American journal of physiology. Renal physiology, 2001-10, Vol.281 (4), p.F579-F596

2001

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Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma

Molecular cancer research, 2015-08, Vol.13 (8), p.1227-1237

2015

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Model of albumin reabsorption in the proximal tubule

American journal of physiology. Renal physiology, 2007-01, Vol.292 (1), p.F430-F439

2007

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Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition

Cancer research (Chicago, Ill.), 2021-04, Vol.81 (8), p.2056-2070

2021

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EGF augments TGFβ-induced epithelial-mesenchymal transition by promoting SHP2 binding to GAB1

Journal of cell science, 2015-11, Vol.128 (21), p.3898-3909

2015

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Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells

Cancer gene therapy, 2024-06, Vol.31 (6), p.851-860

2024

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ERK-dependent suicide gene therapy for selective targeting of RTK/RAS-driven cancers

Molecular therapy, 2021-04, Vol.29 (4), p.1585-1601

2021

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Correction: Disrupting the transmembrane domain–mediated oligomerization of protein tyrosine phosphatase receptor J inhibits EGFR-driven cancer cell phenotypes

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102416-102416, Article 102416

2022

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Understanding how transmembrane domains regulate interactions between human BST-2 and the SARS-CoV-2 accessory protein ORF7a

Biochimica et biophysica acta. Biomembranes, 2023-08, Vol.1865 (6), p.184174-184174, Article 184174

2023

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Regulation of EGFR trafficking and cell signaling by Sprouty2 and MIG6 in lung cancer cells

Journal of cell science, 2013-10, Vol.126 (Pt 19), p.4339-4348

2013

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Disrupting the transmembrane domain–mediated oligomerization of protein tyrosine phosphatase receptor J inhibits EGFR-driven cancer cell phenotypes

The Journal of biological chemistry, 2019-12, Vol.294 (49), p.18796-18806

2019

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Effects of Proximal Tubule Shortening on Protein Excretion in a Lowe Syndrome Model

Journal of the American Society of Nephrology, 2020-01, Vol.31 (1), p.67-83

2020

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Mechanistic and data-driven models of cell signaling: Tools for fundamental discovery and rational design of therapy

Current opinion in systems biology, 2021-12, Vol.28, p.100349, Article 100349

2021

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Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells

Molecular biology of the cell, 2019-02, Vol.30 (4), p.506-523

2019

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Cell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process

A computational modeling approach for predicting multicell spheroid patterns based on signaling-induced differential adhesion

Correction: A computational modeling approach for predicting multicell spheroid patterns based on signaling-induced differential adhesion

Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling

Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors

p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state

Computational Analysis of the Regulation of EGFR by Protein Tyrosine Phosphatases

EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR

CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer

ERK1/2 Blockade Prevents Epithelial―Mesenchymal Transition in Lung Cancer Cells and Promotes Their Sensitivity to EGFR Inhibition

Structural determinants of glomerular permeability

Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma

Model of albumin reabsorption in the proximal tubule

Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition

EGF augments TGFβ-induced epithelial-mesenchymal transition by promoting SHP2 binding to GAB1

Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells

ERK-dependent suicide gene therapy for selective targeting of RTK/RAS-driven cancers

Correction: Disrupting the transmembrane domain–mediated oligomerization of protein tyrosine phosphatase receptor J inhibits EGFR-driven cancer cell phenotypes

Understanding how transmembrane domains regulate interactions between human BST-2 and the SARS-CoV-2 accessory protein ORF7a

Regulation of EGFR trafficking and cell signaling by Sprouty2 and MIG6 in lung cancer cells

Disrupting the transmembrane domain–mediated oligomerization of protein tyrosine phosphatase receptor J inhibits EGFR-driven cancer cell phenotypes

Effects of Proximal Tubule Shortening on Protein Excretion in a Lowe Syndrome Model

Mechanistic and data-driven models of cell signaling: Tools for fundamental discovery and rational design of therapy

Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells

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