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Synthetic Approaches to the New Drugs Approved During 2015

Journal of medicinal chemistry, 2017-08, Vol.60 (15), p.6480-6515

2017

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Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue

ACS chemical biology, 2017-08, Vol.12 (8), p.2015-2020

2017

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Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Chembiochem : a European journal of chemical biology, 2016-10, Vol.17 (20), p.1925-1930

2016

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Enantioselective Construction of All-Carbon Quaternary Centers by Branch-Selective Pd-Catalyzed Allyl–Allyl Cross-Coupling

Journal of the American Chemical Society, 2011-06, Vol.133 (25), p.9716-9719

2011

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Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes

ACS chemical biology, 2015-04, Vol.10 (4), p.1094-1098

2015

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Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis

Organic letters, 2015-03, Vol.17 (6), p.1405-1408

2015

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Long‐term consequences of peri‐adolescent social isolation on social preference, anxiety‐like behaviour, and vasopressin neural circuitry of male and female rats

The European journal of neuroscience, 2021-12, Vol.54 (11), p.7790-7804

2021

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Synthetic approaches to the 2014 new drugs

Bioorganic & medicinal chemistry, 2016-05, Vol.24 (9), p.1937-1980

2016

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Synthetic approaches to the 2013 new drugs

Bioorganic & medicinal chemistry, 2015-05, Vol.23 (9), p.1895-1922

2015

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Investigation of social, affective, and locomotor behavior of adolescent Brattleboro rats reveals a link between vasopressin's actions on arousal and social behavior

Hormones and behavior, 2018-11, Vol.106, p.1-9

2018

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Catalytic Enantioselective Allyl–Allyl Cross-Coupling with a Borylated Allylboronate

Organic letters, 2013-04, Vol.15 (7), p.1432-1435

2013

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Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA)

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.3094-3108

2017

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Synthetic approaches to the 2012 new drugs

Bioorganic & medicinal chemistry, 2014-04, Vol.22 (7), p.2005-2032

2014

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Photoperiod Regulates Hypothalamic miR-155 Gene Expression in Female, but Not Male, Siberian Hamsters (Phodopus sungorus)

Behavioral neuroscience, 2019-04, Vol.133 (2), p.240-246

2019

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Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells

Organic & biomolecular chemistry, 2016-01, Vol.14 (26), p.6179-6183

2016

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The scheduling of adolescence with Netrin-1 and UNC5C

eLife, 2024-07, Vol.12

2024

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Correction to Synthetic Approaches to the New Drugs Approved During 2015

Journal of medicinal chemistry, 2017-10, Vol.60 (20), p.8680-8680

2017

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Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques

ACS combinatorial science, 2016-10, Vol.18 (10), p.611-615

2016

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A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

Molecular bioSystems, 2015-01, Vol.11 (10), p.2709-2712

2015

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Intramolecular thermal allenyne [2+2] cycloadditions: facile construction of the 5–6–4 ring core of sterpurene

Tetrahedron letters, 2008-01, Vol.49 (2), p.376-378

2008

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Allylation of Nitrosobenzene with Pinacol Allylboronates. A Regioselective Complement to Peroxide Oxidation

Organic letters, 2010-09, Vol.12 (17), p.3796-3799

2010

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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10415-10439

2018

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Progress toward the Total Synthesis of Frondosin C

Organic letters, 2006-10, Vol.8 (22), p.5153-5156

2006

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Synthesis of Seven-Membered Carbocyclic Rings via a Microwave-Assisted Tandem Oxyanionic 5-exo dig Cyclization−Claisen Rearrangement Process

Journal of organic chemistry, 2007-08, Vol.72 (17), p.6624-6627

2007

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Total syntheses of (±)-frondosin C and (±)-8- epi-frondosin C via a tandem anionic 5- exo dig cyclization–Claisen rearrangement sequence

Tetrahedron, 2007-02, Vol.63 (9), p.1899-1906

2007

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Synthetic Approaches to the New Drugs Approved During 2015

Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Enantioselective Construction of All-Carbon Quaternary Centers by Branch-Selective Pd-Catalyzed Allyl–Allyl Cross-Coupling

Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes

Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis

Long‐term consequences of peri‐adolescent social isolation on social preference, anxiety‐like behaviour, and vasopressin neural circuitry of male and female rats

Synthetic approaches to the 2014 new drugs

Synthetic approaches to the 2013 new drugs

Investigation of social, affective, and locomotor behavior of adolescent Brattleboro rats reveals a link between vasopressin's actions on arousal and social behavior

Catalytic Enantioselective Allyl–Allyl Cross-Coupling with a Borylated Allylboronate

Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA)

Synthetic approaches to the 2012 new drugs

Photoperiod Regulates Hypothalamic miR-155 Gene Expression in Female, but Not Male, Siberian Hamsters (Phodopus sungorus)

Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells

The scheduling of adolescence with Netrin-1 and UNC5C

Correction to Synthetic Approaches to the New Drugs Approved During 2015

Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

Intramolecular thermal allenyne [2+2] cycloadditions: facile construction of the 5–6–4 ring core of sterpurene

Allylation of Nitrosobenzene with Pinacol Allylboronates. A Regioselective Complement to Peroxide Oxidation

Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Progress toward the Total Synthesis of Frondosin C

Synthesis of Seven-Membered Carbocyclic Rings via a Microwave-Assisted Tandem Oxyanionic 5-exo dig Cyclization−Claisen Rearrangement Process

Total syntheses of (±)-frondosin C and (±)-8- epi-frondosin C via a tandem anionic 5- exo dig cyclization–Claisen rearrangement sequence

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