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Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria

The American journal of tropical medicine and hygiene, 2006-07, Vol.75 (1), p.155-161

2006

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Evidence for the shikimate pathway in apicomplexan parasites

Nature (London), 1998-06, Vol.393 (6687), p.801-805

1998

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Lengthy antimalarial activity of atovaquone in human plasma following atovaquone-proguanil administration

Antimicrobial agents and chemotherapy, 2005-10, Vol.49 (10), p.4421-4422

2005

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The Presence of Leukocytes in Ex Vivo Assays Significantly Increases the 50-Percent Inhibitory Concentrations of Artesunate and Chloroquine against Plasmodium vivax and Plasmodium falciparum

Antimicrobial Agents and Chemotherapy, 2011-03, Vol.55 (3), p.1300-1304

2011

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Cholic Acid Derivatives as 1,2,4,5-Tetraoxane Carriers: Structure and Antimalarial and Antiproliferative Activity

Journal of medicinal chemistry, 2000-08, Vol.43 (17), p.3274-3282

2000

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Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria

The American journal of tropical medicine and hygiene, 2004-01, Vol.70 (1), p.20-26

2004

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Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine–pyrimethamine resistance in malaria-infected patients from Nigeria

Acta tropica, 2005-09, Vol.95 (3), p.183-193

2005

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Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand

The American journal of tropical medicine and hygiene, 1996-01, Vol.54 (1), p.62-66

1996

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Mefloquine Pharmacokinetic-Pharmacodynamic Models: Implications for Dosing and Resistance

Antimicrobial Agents and Chemotherapy, 2000-12, Vol.44 (12), p.3414-3424

2000

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Cardiac effects of antimalarial treatment with halofantrine

The Lancet (British edition), 1993-04, Vol.341 (8852), p.1054-1056

1993

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New class of small nonpeptidyl compounds blocks Plasmodium falciparum development in vitro by inhibiting plasmepsins

Antimicrobial agents and chemotherapy, 2001-09, Vol.45 (9), p.2577-2584

2001

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The epidemiology of malaria in a Karen population on the western border of Thailand

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1996-03, Vol.90 (2), p.105-111

1996

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Neurotoxicity and efficacy of arteether related to its exposure times and exposure levels in rodents

The American journal of tropical medicine and hygiene, 2002-05, Vol.66 (5), p.516-525

2002

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Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum

Nature (London), 1990-05, Vol.345 (6272), p.255-258

1990

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Synthesis and Antimalarial Activity of Sixteen Dispiro-1,2,4,5-tetraoxanes: Alkyl-Substituted 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes

Journal of medicinal chemistry, 2000-07, Vol.43 (14), p.2753-2758

2000

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Randomized Dose-Ranging Study of the Safety and Efficacy of WR 238605 (Tafenoquine) in the Prevention of Relapse of Plasmodium vivax Malaria in Thailand

The Journal of infectious diseases, 1999-10, Vol.180 (4), p.1282-1287

1999

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Linkage disequilibrium between two distinct loci in chromosomes 5 and 7 of Plasmodium falciparum and in vivo chloroquine resistance in Southwest Nigeria

Parasitology research (1987), 2006-12, Vol.100 (1), p.141-148

2006

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Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria

The American journal of tropical medicine and hygiene, 2001-12, Vol.65 (6), p.717-721

2001

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Comparative bioavailability of oral, rectal, and intramuscular artemether in healthy subjects: use of simultaneous measurement by high performance liquid chromatography and bioassay

British journal of clinical pharmacology, 1996-11, Vol.42 (5), p.599-604

1996

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Syntheses and Antimalarial Activities of 10-Substituted Deoxoartemisinins

Journal of medicinal chemistry, 2000-11, Vol.43 (22), p.4228-4232

2000

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In vitro sensitivity of Plasmodium falciparum to artesunate in Thailand

Bulletin of the World Health Organization, 1999-01, Vol.77 (5), p.392-398

1999

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Methyl-Substituted Dispiro-1,2,4,5-tetraoxanes: Correlations of Structural Studies with Antimalarial Activity

Journal of medicinal chemistry, 2000-03, Vol.43 (6), p.1246-1249

2000

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Antimalarial Drugs Reduce Cytoadherence and Rosetting of Plasmodium falciparum

The Journal of infectious diseases, 1996-03, Vol.173 (3), p.691-698

1996

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Antimalarial activity of new dihydroartemisinin derivatives. 7. 4-(p-Substituted phenyl)-4(R or S)-[10(α or β)-dihydroartemisininoxy]butyric acids

Journal of medicinal chemistry, 1997-04, Vol.40 (9), p.1396-1400

1997

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Efficacy comparison of intravenous artelinate and artesunate in Plasmodium berghei-infected Sprague-Dawley rats

Parasitology, 2003-04, Vol.126 (4), p.283-291

2003

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Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria

Evidence for the shikimate pathway in apicomplexan parasites

Lengthy antimalarial activity of atovaquone in human plasma following atovaquone-proguanil administration

The Presence of Leukocytes in Ex Vivo Assays Significantly Increases the 50-Percent Inhibitory Concentrations of Artesunate and Chloroquine against Plasmodium vivax and Plasmodium falciparum

Cholic Acid Derivatives as 1,2,4,5-Tetraoxane Carriers: Structure and Antimalarial and Antiproliferative Activity

Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria

Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine–pyrimethamine resistance in malaria-infected patients from Nigeria

Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand

Mefloquine Pharmacokinetic-Pharmacodynamic Models: Implications for Dosing and Resistance

Cardiac effects of antimalarial treatment with halofantrine

New class of small nonpeptidyl compounds blocks Plasmodium falciparum development in vitro by inhibiting plasmepsins

The epidemiology of malaria in a Karen population on the western border of Thailand

Neurotoxicity and efficacy of arteether related to its exposure times and exposure levels in rodents

Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum

Synthesis and Antimalarial Activity of Sixteen Dispiro-1,2,4,5-tetraoxanes: Alkyl-Substituted 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes

Randomized Dose-Ranging Study of the Safety and Efficacy of WR 238605 (Tafenoquine) in the Prevention of Relapse of Plasmodium vivax Malaria in Thailand

Linkage disequilibrium between two distinct loci in chromosomes 5 and 7 of Plasmodium falciparum and in vivo chloroquine resistance in Southwest Nigeria

Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria

Comparative bioavailability of oral, rectal, and intramuscular artemether in healthy subjects: use of simultaneous measurement by high performance liquid chromatography and bioassay

Syntheses and Antimalarial Activities of 10-Substituted Deoxoartemisinins

In vitro sensitivity of Plasmodium falciparum to artesunate in Thailand

Methyl-Substituted Dispiro-1,2,4,5-tetraoxanes: Correlations of Structural Studies with Antimalarial Activity

Antimalarial Drugs Reduce Cytoadherence and Rosetting of Plasmodium falciparum

Antimalarial activity of new dihydroartemisinin derivatives. 7. 4-(p-Substituted phenyl)-4(R or S)-[10(α or β)-dihydroartemisininoxy]butyric acids

Efficacy comparison of intravenous artelinate and artesunate in Plasmodium berghei-infected Sprague-Dawley rats

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