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Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation

mBio, 2024-08, Vol.15 (8), p.e0111724

2024

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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16272-16277

2008

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Sirolimus and Other Mechanistic Target of Rapamycin Inhibitors Directly Activate Latent Pathogenic Human Polyomavirus Replication

The Journal of infectious diseases, 2021-10, Vol.224 (7), p.1160-1169

2021

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Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7

Cell host & microbe, 2013-08, Vol.14 (2), p.125-135

2013

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CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation

Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (19), p.5875-5882

2015

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Identification of the Merkel Cell Polyomavirus Large Tumor Antigen Ubiquitin Conjugation Residue

International journal of molecular sciences, 2021-07, Vol.22 (13), p.7169

2021

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Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors

International journal of cancer, 2009-09, Vol.125 (6), p.1243-1249

2009

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Merkel Cell Polyomavirus Large T Antigen Unique Domain Regulates Its Own Protein Stability and Cell Growth

Viruses, 2020-09, Vol.12 (9), p.1043

2020

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The T Antigen Locus of Merkel Cell Polyomavirus Downregulates Human Toll-Like Receptor 9 Expression

Journal of Virology, 2013-12, Vol.87 (23), p.13009-13019

2013

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The Minimum Replication Origin of Merkel Cell Polyomavirus Has a Unique Large T-Antigen Loading Architecture and Requires Small T-Antigen Expression for Optimal Replication

Journal of Virology, 2009-12, Vol.83 (23), p.12118-12128

2009

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Cellular and viral factors regulating Merkel cell polyomavirus replication

PloS one, 2011-07, Vol.6 (7), p.e22468-e22468

2011

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Complex Alternative Cytoplasmic Protein Isoforms of the Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Generated through Noncanonical Translation Initiation

Journal of Virology, 2013-03, Vol.87 (5), p.2744-2755

2013

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Therapeutic Potential of 5'-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma

Viruses, 2022-08, Vol.14 (9), p.1848

2022

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Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain

Cells (Basel, Switzerland), 2023-01, Vol.12 (3), p.380

2023

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Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1

Oncogene, 2005-10, Vol.24 (44), p.6617-6625

2005

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Human DNA tumor viruses generate alternative reading frame proteins through repeat sequence recoding

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.E4342-E4349

2014

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Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Mimics Epstein-Barr Virus EBNA1 Immune Evasion through Central Repeat Domain Effects on Protein Processing

Journal of Virology, 2007-08, Vol.81 (15), p.8225-8235

2007

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The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation

Virology (New York, N.Y.), 2011-04, Vol.412 (2), p.357-365

2011

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Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene

Nucleic acids research, 2004, Vol.32 (7), p.2202-2213

2004

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Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53

Journal of general virology, 2007-08, Vol.88 (8), p.2144-2154

2007

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Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

The Journal of clinical investigation, 2011-09, Vol.121 (9), p.3623-3634

2011

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Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (20), p.E4040-E4047

2017

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Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion

Journal of virology, 2020-09, Vol.94 (19)

2020

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Activation of the Human Endogenous Retrovirus W Long Terminal Repeat by Herpes Simplex Virus Type 1 Immediate Early Protein 1

Molecules and Cells, 2003, 15(1), , pp.75-80

2003

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Surface charge of Merkel cell polyomavirus small T antigen determines cell transformation through allosteric FBW7 WD40 domain targeting

Oncogenesis (New York, NY), 2020-05, Vol.9 (5), p.53-53, Article 53

2020

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Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

Sirolimus and Other Mechanistic Target of Rapamycin Inhibitors Directly Activate Latent Pathogenic Human Polyomavirus Replication

Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7

CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation

Identification of the Merkel Cell Polyomavirus Large Tumor Antigen Ubiquitin Conjugation Residue

Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors

Merkel Cell Polyomavirus Large T Antigen Unique Domain Regulates Its Own Protein Stability and Cell Growth

The T Antigen Locus of Merkel Cell Polyomavirus Downregulates Human Toll-Like Receptor 9 Expression

The Minimum Replication Origin of Merkel Cell Polyomavirus Has a Unique Large T-Antigen Loading Architecture and Requires Small T-Antigen Expression for Optimal Replication

Cellular and viral factors regulating Merkel cell polyomavirus replication

Complex Alternative Cytoplasmic Protein Isoforms of the Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Generated through Noncanonical Translation Initiation

Therapeutic Potential of 5'-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma

Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain

Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1

Human DNA tumor viruses generate alternative reading frame proteins through repeat sequence recoding

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Mimics Epstein-Barr Virus EBNA1 Immune Evasion through Central Repeat Domain Effects on Protein Processing

The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation

Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene

Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence

Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion

Activation of the Human Endogenous Retrovirus W Long Terminal Repeat by Herpes Simplex Virus Type 1 Immediate Early Protein 1

Surface charge of Merkel cell polyomavirus small T antigen determines cell transformation through allosteric FBW7 WD40 domain targeting

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