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CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation

PloS one, 2016-03, Vol.11 (3), p.e0151598

2016

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Biological roles of cytochrome P450 1A1, 1A2, and 1B1 enzymes

Archives of Pharmacal Research, 2021, 44(1), , pp.63-83

2021

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Steroid sulfatase deficiency causes cellular senescence and abnormal differentiation by inducing Yippee-like 3 expression in human keratinocytes

Scientific reports, 2021-10, Vol.11 (1), p.20867-20867, Article 20867

2021

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Anticancer activity and metabolic profile alterations by ortho‐topolin riboside in in vitro and in vivo models of non‐small cell lung cancer

The FASEB journal, 2022-02, Vol.36 (2), p.e22127-n/a

2022

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CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity

Oncogene, 2021-05, Vol.40 (18), p.3245-3259

2021

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Combined treatment with auranofin and trametinib induces synergistic apoptosis in breast cancer cells

Journal of Toxicology and Environmental Health, Part A, 2021-01, Vol.84 (2), p.84-94

2021

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7,12‐Dimethylbenz[α]anthracene increases cell proliferation and invasion through induction of Wnt/β‐catenin signaling and EMT process

Environmental toxicology, 2018-07, Vol.33 (7), p.729-742

2018

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Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells

Biomolecules & Therapeutics, 2020, 28(5), , pp.473-481

2020

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CYP1B1 Activates Wnt/β-Catenin Signaling through Suppression of Herc5-Mediated ISGylation for Protein Degradation on β-Catenin in HeLa Cells

한국독성학회지, 2017, 33(3), , pp.211-218

2017

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Cytochrome P450 1B1 promotes cancer cell survival via specificity protein 1 (Sp1)-mediated suppression of death receptor 4

Journal of Toxicology and Environmental Health, Part A, 2018-01, Vol.81 (9), p.278-287

2018

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Unraveling the molecular mechanisms of cell migration impairment and apoptosis associated with steroid sulfatase deficiency: Implications for X-linked ichthyosis

Biochimica et biophysica acta. Molecular basis of disease, 2024-03, Vol.1870 (3), p.167004-167004, Article 167004

2024

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Enhancing the invasive traits of breast cancers by CYP1B1 via regulation of p53 to promote uPAR expression

Biochimica et biophysica acta. Molecular basis of disease, 2024-01, Vol.1870 (1), p.166868-166868, Article 166868

2024

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Comparative metabolic and lipidomic profiling of human breast cancer cells with different metastatic potentials

Oncotarget, 2016-10, Vol.7 (41), p.67111-67128

2016

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CYP1B1 prevents proteasome-mediated XIAP degradation by inducing PKCε activation and phosphorylation of XIAP

Biochimica et biophysica acta. Molecular cell research, 2019-12, Vol.1866 (12), p.118553-118553, Article 118553

2019

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YPEL3 expression induces cellular senescence via the Hippo signaling pathway in human breast cancer cells

Toxicological research (Seoul), 2023-10, Vol.39 (4), p.711-719

2023

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Role of annexin A5 in cisplatin-induced toxicity in renal cells: molecular mechanism of apoptosis

The Journal of biological chemistry, 2014-01, Vol.289 (4), p.2469-2481

2014

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Human steroid sulfatase induces Wnt/β-catenin signaling and epithelial-mesenchymal transition by upregulating Twist1 and HIF-1α in human prostate and cervical cancer cells

Oncotarget, 2017-09, Vol.8 (37), p.61604-61617

2017

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Human steroid sulfatase enhances aerobic glycolysis through induction of HIF1α and glycolytic enzymes

Biochimica et biophysica acta. Molecular basis of disease, 2019-09, Vol.1865 (9), p.2464-2474

2019

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Annexin A5 suppresses cyclooxygenase-2 expression by downregulating the protein kinase C-ζ-nuclear factor-κB signaling pathway in prostate cancer cells

Oncotarget, 2017-09, Vol.8 (43), p.74263-74275

2017

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Combination treatment with auranofin and nutlin-3a induces synergistic cytotoxicity in breast cancer cells

Journal of Toxicology and Environmental Health, Part A, 2019-05, Vol.82 (10), p.626-637

2019

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Induction of synergistic apoptosis by tetramethoxystilbene and nutlin-3a in human cervical cancer cells

Toxicological research (Seoul), 2022-10, Vol.38 (4), p.591-600

2022

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Discovery of Ezrin Expression as a Potential Biomarker for Chemically Induced Ocular Irritation Using Human Corneal Epithelium Cell Line and a Reconstructed Human Cornea-like Epithelium Model

Toxicological sciences, 2018-10, Vol.165 (2), p.335-346

2018

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Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells

Biomolecules & therapeutics, 2020-09, Vol.28 (5), p.473-481

2020

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Synergistic induction of apoptosis by combination treatment with mesupron and auranofin in human breast cancer cells

Archives of Pharmacal Research, 2017, 40(6), , pp.746-759

2017

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G0/G1 Switch 2 Induces Cell Survival and Metastasis through Integrin-Mediated Signal Transduction in Human Invasive Breast Cancer Cells

Biomolecules & therapeutics, 2019-11, Vol.27 (6), p.591-602

2019

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CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation

Biological roles of cytochrome P450 1A1, 1A2, and 1B1 enzymes

Steroid sulfatase deficiency causes cellular senescence and abnormal differentiation by inducing Yippee-like 3 expression in human keratinocytes

Anticancer activity and metabolic profile alterations by ortho‐topolin riboside in in vitro and in vivo models of non‐small cell lung cancer

CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity

Combined treatment with auranofin and trametinib induces synergistic apoptosis in breast cancer cells

7,12‐Dimethylbenz[α]anthracene increases cell proliferation and invasion through induction of Wnt/β‐catenin signaling and EMT process

Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells

CYP1B1 Activates Wnt/β-Catenin Signaling through Suppression of Herc5-Mediated ISGylation for Protein Degradation on β-Catenin in HeLa Cells

Cytochrome P450 1B1 promotes cancer cell survival via specificity protein 1 (Sp1)-mediated suppression of death receptor 4

Unraveling the molecular mechanisms of cell migration impairment and apoptosis associated with steroid sulfatase deficiency: Implications for X-linked ichthyosis

Enhancing the invasive traits of breast cancers by CYP1B1 via regulation of p53 to promote uPAR expression

Comparative metabolic and lipidomic profiling of human breast cancer cells with different metastatic potentials

CYP1B1 prevents proteasome-mediated XIAP degradation by inducing PKCε activation and phosphorylation of XIAP

YPEL3 expression induces cellular senescence via the Hippo signaling pathway in human breast cancer cells

Role of annexin A5 in cisplatin-induced toxicity in renal cells: molecular mechanism of apoptosis

Human steroid sulfatase induces Wnt/β-catenin signaling and epithelial-mesenchymal transition by upregulating Twist1 and HIF-1α in human prostate and cervical cancer cells

Human steroid sulfatase enhances aerobic glycolysis through induction of HIF1α and glycolytic enzymes

Annexin A5 suppresses cyclooxygenase-2 expression by downregulating the protein kinase C-ζ-nuclear factor-κB signaling pathway in prostate cancer cells

Combination treatment with auranofin and nutlin-3a induces synergistic cytotoxicity in breast cancer cells

Induction of synergistic apoptosis by tetramethoxystilbene and nutlin-3a in human cervical cancer cells

Discovery of Ezrin Expression as a Potential Biomarker for Chemically Induced Ocular Irritation Using Human Corneal Epithelium Cell Line and a Reconstructed Human Cornea-like Epithelium Model

Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells

Synergistic induction of apoptosis by combination treatment with mesupron and auranofin in human breast cancer cells

G0/G1 Switch 2 Induces Cell Survival and Metastasis through Integrin-Mediated Signal Transduction in Human Invasive Breast Cancer Cells

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