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Biosynthetic studies on terpenoids produced by Streptomyces

Journal of antibiotics, 2017-07, Vol.70 (7), p.811-818

Kuzuyama, Tomohisa

2017

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Recent advances in the biosynthesis of nucleoside antibiotics

Journal of antibiotics, 2019-12, Vol.72 (12), p.913-923

2019

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Terpene synthases are widely distributed in bacteria

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (3), p.857-862

2015

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Biosynthetic pathways and enzymes involved in the production of phosphonic acid natural products

Bioscience, biotechnology, and biochemistry, 2021-01, Vol.85 (1), p.42-52

2021

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Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria

Journal of the American Chemical Society, 2018-07, Vol.140 (29), p.9083-9086

2018

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Biosynthesis of the nucleoside antibiotic angustmycins: identification and characterization of the biosynthetic gene cluster reveal unprecedented dehydratase required for exo-glycal formation

Journal of antibiotics, 2021-11, Vol.74 (11), p.830-833

2021

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Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis

Proceedings of the Japan Academy, Series B, 2012/03/09, Vol.88(3), pp.41-52

2012

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Discovery of type II polyketide synthase-like enzymes for the biosynthesis of cispentacin

Nature communications, 2023-12, Vol.14 (1), p.8065-8065, Article 8065

2023

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Cryptic Oxidative Transamination of Hydroxynaphthoquinone in Natural Product Biosynthesis

Journal of the American Chemical Society, 2022-03, Vol.144 (12), p.5435-5440

2022

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Stable isotope and chemical inhibition analyses suggested the existence of a non-mevalonate-like pathway in the yeast Yarrowia lipolytica

Scientific reports, 2021-03, Vol.11 (1), p.5598-5598, Article 5598

2021

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A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster

Journal of antibiotics, 2021-05, Vol.74 (5), p.354-358

2021

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Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units

Bioscience, biotechnology, and biochemistry, 2002-08, Vol.66 (8), p.1619-1627

KUZUYAMA, Tomohisa

2002

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Recent Advances in the Biosynthesis of Carbazoles Produced by Actinomycetes

Biomolecules (Basel, Switzerland), 2020-08, Vol.10 (8), p.1147

2020

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Biosynthetic Origin of the Hydroxamic Acid Moiety of Trichostatin A: Identification of Unprecedented Enzymatic Machinery Involved in Hydroxylamine Transfer

Journal of the American Chemical Society, 2017-05, Vol.139 (20), p.6799-6802

2017

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An Unprecedented Cyclization Mechanism in the Biosynthesis of Carbazole Alkaloids in Streptomyces

Angewandte Chemie International Edition, 2019-09, Vol.58 (38), p.13349-13353

International ed. in English, 2019

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Total Synthesis and Stereochemistry Assignment of Nucleoside Antibiotic A‐94964

Angewandte Chemie International Edition, 2022-03, Vol.61 (14), p.e202200818-n/a

International ed. in English, 2022

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Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination

Journal of the American Chemical Society, 2022-09, Vol.144 (35), p.16164-16170

2022

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Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms

Journal of antibiotics, 2017-05, Vol.70 (5), p.616-624

2017

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Biosynthesis of Versipelostatin: Identification of an Enzyme-Catalyzed [4+2]-Cycloaddition Required for Macrocyclization of Spirotetronate-Containing Polyketides

Journal of the American Chemical Society, 2015-01, Vol.137 (2), p.572-575

2015

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Methylcobalamin-Dependent Radical SAM C‑Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C‑Methylation in Fosfomycin Biosynthesis

Biochemistry (Easton), 2017-07, Vol.56 (28), p.3519-3522

2017

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Involvement of subdomain II in the recognition of acetyl‐CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius

The FEBS journal, 2021-03, Vol.288 (6), p.1975-1988

2021

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Cyclolavandulyl Skeleton Biosynthesis via Both Condensation and Cyclization Catalyzed by an Unprecedented Member of the cis-Isoprenyl Diphosphate Synthase Superfamily

Journal of the American Chemical Society, 2014-04, Vol.136 (13), p.4837-4840

2014

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Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products

Nature, 2005-06, Vol.435 (7044), p.983-987

2005

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An Unusual Terpene Cyclization Mechanism Involving a Carbon-Carbon Bond Rearrangement

Angewandte Chemie (International ed.), 2015-03, Vol.54 (14), p.4353-4356

International ed. in English, 2015

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Diversity of the biosynthesis of the isoprene units

Natural product reports, 2003-04, Vol.20 (2), p.171-183

2003

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Biosynthetic studies on terpenoids produced by Streptomyces

Recent advances in the biosynthesis of nucleoside antibiotics

Terpene synthases are widely distributed in bacteria

Biosynthetic pathways and enzymes involved in the production of phosphonic acid natural products

Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria

Biosynthesis of the nucleoside antibiotic angustmycins: identification and characterization of the biosynthetic gene cluster reveal unprecedented dehydratase required for exo-glycal formation

Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis

Discovery of type II polyketide synthase-like enzymes for the biosynthesis of cispentacin

Cryptic Oxidative Transamination of Hydroxynaphthoquinone in Natural Product Biosynthesis

Stable isotope and chemical inhibition analyses suggested the existence of a non-mevalonate-like pathway in the yeast Yarrowia lipolytica

A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster

Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units

Recent Advances in the Biosynthesis of Carbazoles Produced by Actinomycetes

Biosynthetic Origin of the Hydroxamic Acid Moiety of Trichostatin A: Identification of Unprecedented Enzymatic Machinery Involved in Hydroxylamine Transfer

An Unprecedented Cyclization Mechanism in the Biosynthesis of Carbazole Alkaloids in Streptomyces

Total Synthesis and Stereochemistry Assignment of Nucleoside Antibiotic A‐94964

Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination

Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms

Biosynthesis of Versipelostatin: Identification of an Enzyme-Catalyzed [4+2]-Cycloaddition Required for Macrocyclization of Spirotetronate-Containing Polyketides

Methylcobalamin-Dependent Radical SAM C‑Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C‑Methylation in Fosfomycin Biosynthesis

Involvement of subdomain II in the recognition of acetyl‐CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius

Cyclolavandulyl Skeleton Biosynthesis via Both Condensation and Cyclization Catalyzed by an Unprecedented Member of the cis-Isoprenyl Diphosphate Synthase Superfamily

Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products

An Unusual Terpene Cyclization Mechanism Involving a Carbon-Carbon Bond Rearrangement

Diversity of the biosynthesis of the isoprene units

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