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Recent advances in drug substance development – prodrug strategies for enhancing the bioavailability and potency of antiviral nucleosides

Journal of medical science, 2023-09, Vol.92 (3), p.e878

Kutner, Andrzej

2023

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Vitamins D: Relationship between Structure and Biological Activity

International journal of molecular sciences, 2018-07, Vol.19 (7), p.2119

2018

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Nonaqueous Capillary Electrophoretic Separation of Analogs of (24R)-1,24-Dihydroxyvitamin D3 Derivative as Predicted by Quantum Chemical Calculations

Molecules (Basel, Switzerland), 2023-06, Vol.28 (13), p.5055

2023

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Novel Strategies in the Development of New Therapies, Drug Substances, and Drug Carriers Volume II

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5621

2023

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Structure and the Anticancer Activity of Vitamin D Receptor Agonists

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6624

2024

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Molecular Interactions of Selective Agonists and Antagonists with the Retinoic Acid Receptor γ

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6568

2024

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Novel Strategies in the Development of New Therapies, Drug Substances, and Drug Carriers Volume I

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6635

2022

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First Experimental Quantitative Charge Density Studies of Advanced Intermediate of Vitamin D Analogues

Molecules (Basel, Switzerland), 2022-03, Vol.27 (6), p.1757

2022

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In Silico Prediction of the Metabolic Resistance of Vitamin D Analogs against CYP3A4 Metabolizing Enzyme

International journal of molecular sciences, 2022-07, Vol.23 (14), p.7845

2022

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Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase

The Journal of steroid biochemistry and molecular biology, 2019-06, Vol.190, p.139-151

2019

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Relation Between Crystal Structures of Precursors and Final Products: Example of Vitamin D Intermediates

Molecules (Basel, Switzerland), 2020-04, Vol.25 (8), p.1802

2020

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Dimethyl fumarate and vitamin D derivatives cooperatively enhance VDR and Nrf2 signaling in differentiating AML cells in vitro and inhibit leukemia progression in a xenograft mouse model

The Journal of steroid biochemistry and molecular biology, 2019-04, Vol.188, p.8-16

2019

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Differential Response of Lung Cancer Cells, with Various Driver Mutations, to Plant Polyphenol Resveratrol and Vitamin D Active Metabolite PRI-2191

International journal of molecular sciences, 2021-03, Vol.22 (5), p.2354

2021

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Antiproliferative activity of side-chain truncated vitamin D analogs (PRI-1203 and PRI-1204) against human malignant melanoma cell lines

European journal of pharmacology, 2020-08, Vol.881, p.173170-173170, Article 173170

2020

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Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models

International journal of molecular sciences, 2021-03, Vol.22 (5), p.2781

2021

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Micro-RNAs in Response to Active Forms of Vitamin D3 in Human Leukemia and Lymphoma Cells

International journal of molecular sciences, 2022-04, Vol.23 (9), p.5019

2022

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Vitamin D Analogs Regulate the Vitamin D System and Cell Viability in Ovarian Cancer Cells

International journal of molecular sciences, 2021-12, Vol.23 (1), p.172

2021

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Synthesis, CYP24A1-Dependent Metabolism and Antiproliferative Potential against Colorectal Cancer Cells of 1,25-Dihydroxyvitamin D2 Derivatives Modified at the Side Chain and the A-Ring

International journal of molecular sciences, 2020-01, Vol.21 (2), p.642

2020

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Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model

International journal of molecular sciences, 2015-11, Vol.16 (11), p.27191-27207

2015

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Investigating the Role of VDR and Megalin in Semi-Selectivity of Side-Chain Modified 19- nor Analogs of Vitamin D

International journal of molecular sciences, 2019-08, Vol.20 (17), p.4183

2019

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Polymorphism of VDR Gene and the Sensitivity of Human Leukemia and Lymphoma Cells to Active Forms of Vitamin D

Cancers, 2022-01, Vol.14 (2), p.387

2022

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Antiproliferative Activity of Double Point Modified Analogs of 1,25-Dihydroxyvitamin D₂ Against Human Malignant Melanoma Cell Lines

International journal of molecular sciences, 2016-01, Vol.17 (1), p.76

2016

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Prodifferentiation Activity of Novel Vitamin D₂ Analogs PRI-1916 and PRI-1917 and Their Combinations with a Plant Polyphenol in Acute Myeloid Leukemia Cells

International journal of molecular sciences, 2016-07, Vol.17 (7), p.1068

2016

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Double point modified analogs of vitamin d as potent activators of vitamin D receptor

Current pharmaceutical design, 2015-01, Vol.21 (13), p.1741-1763

2015

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Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol

International journal of molecular sciences, 2015-10, Vol.16 (10), p.24873-24894

2015

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Recent advances in drug substance development – prodrug strategies for enhancing the bioavailability and potency of antiviral nucleosides

Vitamins D: Relationship between Structure and Biological Activity

Nonaqueous Capillary Electrophoretic Separation of Analogs of (24R)-1,24-Dihydroxyvitamin D3 Derivative as Predicted by Quantum Chemical Calculations

Novel Strategies in the Development of New Therapies, Drug Substances, and Drug Carriers Volume II

Structure and the Anticancer Activity of Vitamin D Receptor Agonists

Molecular Interactions of Selective Agonists and Antagonists with the Retinoic Acid Receptor γ

Novel Strategies in the Development of New Therapies, Drug Substances, and Drug Carriers Volume I

First Experimental Quantitative Charge Density Studies of Advanced Intermediate of Vitamin D Analogues

In Silico Prediction of the Metabolic Resistance of Vitamin D Analogs against CYP3A4 Metabolizing Enzyme

Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase

Relation Between Crystal Structures of Precursors and Final Products: Example of Vitamin D Intermediates

Dimethyl fumarate and vitamin D derivatives cooperatively enhance VDR and Nrf2 signaling in differentiating AML cells in vitro and inhibit leukemia progression in a xenograft mouse model

Differential Response of Lung Cancer Cells, with Various Driver Mutations, to Plant Polyphenol Resveratrol and Vitamin D Active Metabolite PRI-2191

Antiproliferative activity of side-chain truncated vitamin D analogs (PRI-1203 and PRI-1204) against human malignant melanoma cell lines

Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models

Micro-RNAs in Response to Active Forms of Vitamin D3 in Human Leukemia and Lymphoma Cells

Vitamin D Analogs Regulate the Vitamin D System and Cell Viability in Ovarian Cancer Cells

Synthesis, CYP24A1-Dependent Metabolism and Antiproliferative Potential against Colorectal Cancer Cells of 1,25-Dihydroxyvitamin D2 Derivatives Modified at the Side Chain and the A-Ring

Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model

Investigating the Role of VDR and Megalin in Semi-Selectivity of Side-Chain Modified 19- nor Analogs of Vitamin D

Polymorphism of VDR Gene and the Sensitivity of Human Leukemia and Lymphoma Cells to Active Forms of Vitamin D

Antiproliferative Activity of Double Point Modified Analogs of 1,25-Dihydroxyvitamin D₂ Against Human Malignant Melanoma Cell Lines

Prodifferentiation Activity of Novel Vitamin D₂ Analogs PRI-1916 and PRI-1917 and Their Combinations with a Plant Polyphenol in Acute Myeloid Leukemia Cells

Double point modified analogs of vitamin d as potent activators of vitamin D receptor

Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol

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