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Transcriptional signatures measured in whole blood correlate with protection against tuberculosis in inbred and outbred mice

PloS one, 2023-08, Vol.18 (8), p.e0289358-e0289358

2023

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Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity

PloS one, 2021-03, Vol.16 (3), p.e0249142-e0249142

2021

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Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice

PLoS pathogens, 2024-03, Vol.20 (3), p.e1012069-e1012069

2024

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Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9

PloS one, 2020-08, Vol.15 (8), p.e0237034-e0237034

2020

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Intravenous BCG Vaccination of Diversity Outbred Mice Results in Moderately Enhanced Protection against Challenge with Mycobacterium tuberculosis Compared to Intradermal Vaccination

Infection and immunity, 2023-07, Vol.91 (7), p.e0016823-e0016823

2023

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Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice

PLoS pathogens, 2024-06, Vol.20 (6), p.e1011915

2024

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The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection

mSphere, 2020-04, Vol.5 (2)

2020

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Host Genetic Background Influences BCG-Induced Antibodies Cross-Reactive to SARS-CoV-2 Spike Protein

Vaccines (Basel), 2024-02, Vol.12 (3), p.242

2024

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Whole genome profiling refines a panel of correlates to predict vaccine efficacy against Mycobacterium tuberculosis

Tuberculosis (Edinburgh, Scotland), 2020-01, Vol.120, p.101895-101895, Article 101895

2020

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Progress, challenges, and opportunities in Francisella vaccine development

Expert review of vaccines, 2016-09, Vol.15 (9), p.1183-1196

2016

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Correlates of Vaccine-Induced Protection against Mycobacterium tuberculosis Revealed in Comparative Analyses of Lymphocyte Populations

Clinical and vaccine immunology, 2015-10, Vol.22 (10), p.1096-1108

2015

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Sequence comparison of Francisella tularensis LVS, LVS-G and LVS-R

Pathogens and disease, 2018-10, Vol.76 (7)

2018

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IL-23 p19 knockout mice exhibit minimal defects in responses to primary and secondary infection with Francisella tularensis LVS

PloS one, 2014-10, Vol.9 (10), p.e109898-e109898

2014

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Interleukin-6 Is Essential for Primary Resistance to Francisella tularensis Live Vaccine Strain Infection

Infection and Immunity, 2013-02, Vol.81 (2), p.585-597

2013

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Immunogenicity and protective efficacy of novel Mycobacterium tuberculosis antigens

Vaccine, 2013-09, Vol.31 (41), p.4641-4646

2013

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GM-CSF has disparate roles during intranasal and intradermal Francisella tularensis infection

Microbes and infection, 2016-12, Vol.18 (12), p.758-767

2016

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The Many Hosts of Mycobacteria 8 (MHM8): A conference report

Tuberculosis (Edinburgh, Scotland), 2020-03, Vol.121 (C), p.101914-101914, Article 101914

2020

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SecA2 Secretion Factor of Mycobacterium tuberculosis Promotes Growth in Macrophages and Inhibits the Host Immune Response

Infection and Immunity, 2006-12, Vol.74 (12), p.6855-6864

2006

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The Accessory SecA2 System of Mycobacteria Requires ATP Binding and the Canonical SecA1

The Journal of biological chemistry, 2009-04, Vol.284 (15), p.9927-9936

2009

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Poly (Lactide-co-Glycolide) microspheres in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen 85B

Pharmaceutical research, 2007-10, Vol.24 (10), p.1834-1843

2007

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Two Nonredundant SecA Homologues Function in Mycobacteria

Journal of Bacteriology, 2001-12, Vol.183 (24), p.6979-6990

2001

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Legionella pneumophila Mip, a Surface-Exposed Peptidylproline cis-trans-Isomerase, Promotes the Presence of Phospholipase C-Like Activity in Culture Supernatants

Infection and Immunity, 2006-09, Vol.74 (9), p.5152-5160

2006

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Legionella pneumophila Major Acid Phosphatase and Its Role in Intracellular Infection

Infection and Immunity, 2001-01, Vol.69 (1), p.177-185

2001

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Production of IFN-[gamma] by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9

PloS one, 2020-08, Vol.15 (8), p.e0237034

2020

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Transcriptional signatures measured in whole blood correlate with protection against tuberculosis in inbred and outbred mice

Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity

Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice

Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9

Intravenous BCG Vaccination of Diversity Outbred Mice Results in Moderately Enhanced Protection against Challenge with Mycobacterium tuberculosis Compared to Intradermal Vaccination

Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice

The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection

Host Genetic Background Influences BCG-Induced Antibodies Cross-Reactive to SARS-CoV-2 Spike Protein

Whole genome profiling refines a panel of correlates to predict vaccine efficacy against Mycobacterium tuberculosis

Progress, challenges, and opportunities in Francisella vaccine development

Correlates of Vaccine-Induced Protection against Mycobacterium tuberculosis Revealed in Comparative Analyses of Lymphocyte Populations

Sequence comparison of Francisella tularensis LVS, LVS-G and LVS-R

IL-23 p19 knockout mice exhibit minimal defects in responses to primary and secondary infection with Francisella tularensis LVS

Interleukin-6 Is Essential for Primary Resistance to Francisella tularensis Live Vaccine Strain Infection

Immunogenicity and protective efficacy of novel Mycobacterium tuberculosis antigens

GM-CSF has disparate roles during intranasal and intradermal Francisella tularensis infection

The Many Hosts of Mycobacteria 8 (MHM8): A conference report

SecA2 Secretion Factor of Mycobacterium tuberculosis Promotes Growth in Macrophages and Inhibits the Host Immune Response

The Accessory SecA2 System of Mycobacteria Requires ATP Binding and the Canonical SecA1

Poly (Lactide-co-Glycolide) microspheres in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen 85B

Two Nonredundant SecA Homologues Function in Mycobacteria

Legionella pneumophila Mip, a Surface-Exposed Peptidylproline cis-trans-Isomerase, Promotes the Presence of Phospholipase C-Like Activity in Culture Supernatants

Legionella pneumophila Major Acid Phosphatase and Its Role in Intracellular Infection

Production of IFN-[gamma] by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9

Building the concept for WHO Evidence Considerations for Vaccine Policy (ECVP): Tuberculosis vaccines intended for adults and adolescents as a test case

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