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Obesity among HIV-infected persons: impact of weight on CD4 cell count

AIDS (London), 2010-04, Vol.24 (7), p.1069-1072

2010

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Comparative Outcomes of the Transareolar Approach: Systematic Review And Case Series

Plastic and reconstructive surgery. Global open, 2023-10, Vol.11 (10S), p.144-144

2023

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Transfusion medicine and safety

Biologicals, 2009-04, Vol.37 (2), p.62-70

2009

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9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors

Bioorganic & medicinal chemistry letters, 2015-07, Vol.25 (14), p.2809-2812

2015

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Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors

Bioorganic & medicinal chemistry, 2012-03, Vol.20 (6), p.1961-1972

2012

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Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1233-1237

2007

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1609-1612

2004

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Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors: SAR of a series of 3-[6-(4-substituted-piperazin-1-yl)-4-methyl-1H-benzimidazol-2-yl]-1H-pyridine-2-one

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3182-3185

2010

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SAR of PXR transactivation in benzimidazole-based IGF-1R kinase inhibitors

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (5), p.1744-1748

2010

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Discovery and initial SAR of 3-(1 H-benzo[ d]imidazol-2-yl)pyridin-2(1 H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R)

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2317-2321

2007

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Balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-IR inhibitors

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4075-4080

2008

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Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors: The Chemistry Biology Interface

Bioorganic & medicinal chemistry, 2012, Vol.20 (6), p.1961-1972

2012

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2-(1 H-Imidazol-4-yl)ethanamine and 2-(1 H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (5), p.1702-1707

2008

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Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors: SAR of a series of 3-[6-(4-substituted-piperazin-1-yl)-4-methyl-1 H-benzimidazol-2-yl]-1 H-pyridine-2-one

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (10), p.3182-3185

2010

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β-d-glucopyranosyl]-5H,13H-benzo[b]thienyl[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.654-654

2005

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Discovery and initial SAR of 3-(1H-benzo[d|imidaz 2 -yl )pyridin -2 (1H) -ones as inhibitors of insulin-lil growth factor 1-receptor (IGF-1R)

Bioorganic & medicinal chemistry letters, 2007, Vol.17 (8), p.2317-2321

2007

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Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3-a]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp3 Carbon

Organic letters, 2005-03, Vol.7 (7), p.1271-1274

2005

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Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3- a ]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp 3 Carbon

Organic letters, 2005-03, Vol.7 (7), p.1271-1274

2005

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Obesity among HIV-infected persons: impact of weight on CD4 cell count

Discovery of a 2,4-Disubstituted Pyrrolo[1,2-f][1,2,4]triazine Inhibitor (BMS-754807) of Insulin-like Growth Factor Receptor (IGF-1R) Kinase in Clinical Development

Comparative Outcomes of the Transareolar Approach: Systematic Review And Case Series

Discovery of a 1H-Benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

Transfusion medicine and safety

9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors

Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors

Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors

Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors: SAR of a series of 3-[6-(4-substituted-piperazin-1-yl)-4-methyl-1H-benzimidazol-2-yl]-1H-pyridine-2-one

SAR of PXR transactivation in benzimidazole-based IGF-1R kinase inhibitors

Discovery and initial SAR of 3-(1 H-benzo[ d]imidazol-2-yl)pyridin-2(1 H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R)

Balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-IR inhibitors

Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors: The Chemistry Biology Interface

2-(1 H-Imidazol-4-yl)ethanamine and 2-(1 H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924

Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors: SAR of a series of 3-[6-(4-substituted-piperazin-1-yl)-4-methyl-1 H-benzimidazol-2-yl]-1 H-pyridine-2-one

Discovery and initial SAR of 3-(1H-benzo[d|imidaz 2 -yl )pyridin -2 (1H) -ones as inhibitors of insulin-lil growth factor 1-receptor (IGF-1R)

Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3-a]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp3 Carbon

Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3- a ]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp 3 Carbon

Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity

Discovery of a 1 H -Benzoimidazol-2-yl)-1 H -pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

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