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Computational Systems Biology Approaches in Cancer Research

1, 2020

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COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

Scientific data, 2020-05, Vol.7 (1), p.136-136, Article 136

2020

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A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures

Nature communications, 2019-10, Vol.10 (1), p.4808-13, Article 4808

2019

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The Phosphatase PRL-3 Is Involved in Key Steps of Cancer Metastasis

Journal of molecular biology, 2019-08, Vol.431 (17), p.3056-3067

2019

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Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut

Nature communications, 2014-10, Vol.5 (1), p.5005-5005, Article 5005

2014

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Metabolic and signalling network maps integration: application to cross-talk studies and omics data analysis in cancer

BMC bioinformatics, 2019-04, Vol.20 (Suppl 4), p.140-140, Article 140

2019

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Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors

Clinical cancer research, 2017-02, Vol.23 (4), p.1001-1011

2017

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Synthetic lethality between gene defects affecting a single non-essential molecular pathway with reversible steps

PLoS computational biology, 2013-04, Vol.9 (4), p.e1003016

2013

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Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

Scientific data, 2020-07, Vol.7 (1), p.247-247, Article 247

2020

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Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer

Cancer cell, 2018-03, Vol.33 (3), p.463-479.e10

2018

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Network-based approaches for drug response prediction and targeted therapy development in cancer

Biochemical and biophysical research communications, 2015-08, Vol.464 (2), p.386-391

2015

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Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0

Nature protocols, 2019-03, Vol.14 (3), p.639-702

2019

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Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

The EMBO journal, 2010-10, Vol.29 (19), p.3408-3420

2010

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Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice

The EMBO journal, 2008-01, Vol.27 (1), p.224-233

2008

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Network biology elucidates metastatic colon cancer mechanisms

Cell cycle (Georgetown, Tex.), 2015-07, Vol.14 (14), p.2189-2190

2015

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Abstract 1110: AsiDNA induce tumor sensitivity to PARP inhibitors in homologous recombination proficient breast cancer AsiDNA induce tumor sensitivity to PARP inhibitors in homologous recombination proficient breast cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1110-1110

2017

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Community-driven roadmap for integrated disease maps

Briefings in bioinformatics, 2019-03, Vol.20 (2), p.659-670

2019

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Signalling maps in cancer research: construction and data analysis

Database : the journal of biological databases and curation, 2018-01, Vol.2018

2018

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NaviCell Web Service for network-based data visualization

Nucleic acids research, 2015-07, Vol.43 (W1), p.W560-W565

2015

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Application of Atlas of Cancer Signalling Network in preclinical studies

Briefings in bioinformatics, 2019-03, Vol.20 (2), p.701-716

2019

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Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms

NPJ systems biology and applications, 2018-06, Vol.4 (1), p.21-10, Article 21

2018

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The shortest path is not the one you know: application of biological network resources in precision oncology research

Mutagenesis, 2015-03, Vol.30 (2), p.191-204

2015

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NaviCom: a web application to create interactive molecular network portraits using multi-level omics data

Database : the journal of biological databases and curation, 2017, Vol.2017 (1)

2017

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Gene‐ and pathway‐level analyses of iCOGS variants highlight novel signaling pathways underlying familial breast cancer susceptibility

International journal of cancer, 2021-04, Vol.148 (8), p.1895-1909

2021

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Computational Systems Biology Approaches in Cancer Research

COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures

The Phosphatase PRL-3 Is Involved in Key Steps of Cancer Metastasis

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut

Metabolic and signalling network maps integration: application to cross-talk studies and omics data analysis in cancer

Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors

Synthetic lethality between gene defects affecting a single non-essential molecular pathway with reversible steps

Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer

Network-based approaches for drug response prediction and targeted therapy development in cancer

Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0

The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice

Network biology elucidates metastatic colon cancer mechanisms

Abstract 1110: AsiDNA induce tumor sensitivity to PARP inhibitors in homologous recombination proficient breast cancer AsiDNA induce tumor sensitivity to PARP inhibitors in homologous recombination proficient breast cancer

Community-driven roadmap for integrated disease maps

Signalling maps in cancer research: construction and data analysis

NaviCell Web Service for network-based data visualization

Application of Atlas of Cancer Signalling Network in preclinical studies

Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms

The shortest path is not the one you know: application of biological network resources in precision oncology research

NaviCom: a web application to create interactive molecular network portraits using multi-level omics data

Gene‐ and pathway‐level analyses of iCOGS variants highlight novel signaling pathways underlying familial breast cancer susceptibility

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