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Cytokines and Chemokines in SARS-CoV-2 Infections-Therapeutic Strategies Targeting Cytokine Storm

Biomolecules (Basel, Switzerland), 2021-01, Vol.11 (1), p.91

2021

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Therapeutic strategies to target microbial protein-glycosaminoglycan interactions

Biochemical Society transactions, 2018-12, Vol.46 (6), p.1505

2018

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The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6519

2022

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Isolation and Characterization of Heparan Sulfate from Human Lung Tissues

Molecules (Basel, Switzerland), 2021-09, Vol.26 (18), p.5512

2021

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Single domain shark VNAR antibodies neutralize SARS‐CoV‐2 infection in vitro

The FASEB journal, 2021-11, Vol.35 (11), p.e21970-n/a

2021

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Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

Nature medicine, 2009-01, Vol.15 (1), p.97-103

2009

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A combinatorial approach to biophysically characterise chemokine-glycan binding affinities for drug development

Molecules (Basel, Switzerland), 2014-07, Vol.19 (7), p.10618-10634

2014

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A New Monocyte Chemotactic Protein-1/Chemokine CC Motif Ligand-2 Competitor Limiting Neointima Formation and Myocardial Ischemia/Reperfusion Injury in Mice

Journal of the American College of Cardiology, 2010-11, Vol.56 (22), p.1847-1857

2010

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Chemokine Binding to Tenascin-C Influences Chemokine-Induced Immune Cell Migration

International journal of molecular sciences, 2023-10, Vol.24 (19), p.14694

2023

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Molecular dynamics simulations of the chemokine CCL2 in complex with pull down-derived heparan sulfate hexasaccharides

Biochimica et biophysica acta. General subjects, 2019-03, Vol.1863 (3), p.528-533

2019

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Exploring the glycosaminoglycan-protein interaction network by glycan-mediated pull-down proteomics

Electrophoresis, 2016-06, Vol.37 (11), p.1437-1447

2016

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The Molecular Chaperone Hsp90 Modulates Intermediate Steps of Amyloid Assembly of the Parkinson-related Protein α-Synuclein

The Journal of biological chemistry, 2009-11, Vol.284 (45), p.31190-31199

2009

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The Positively Charged COOH-terminal Glycosaminoglycan-binding CXCL9(74–103) Peptide Inhibits CXCL8-induced Neutrophil Extravasation and Monosodium Urate Crystal-induced Gout in Mice

The Journal of biological chemistry, 2015-08, Vol.290 (35), p.21292-21304

2015

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Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2

International journal of molecular sciences, 2023-05, Vol.24 (9), p.8365

2023

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Enoxaparin and Pentosan Polysulfate Bind to the SARS-CoV-2 Spike Protein and Human ACE2 Receptor, Inhibiting Vero Cell Infection

Biomedicines, 2021-12, Vol.10 (1), p.49

2021

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Novel Anti-Inflammatory Peptides Based on Chemokine-Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis

The Journal of immunology (1950), 2018-05, Vol.200 (9), p.3201-3217

2018

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Soluble syndecan-3 binds chemokines, reduces leukocyte migration in vitro and ameliorates disease severity in models of rheumatoid arthritis

Arthritis research & therapy, 2019-07, Vol.21 (1), p.172-172, Article 172

2019

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Glycosaminoglycan-Mediated Downstream Signaling of CXCL8 Binding to Endothelial Cells

International journal of molecular sciences, 2017-12, Vol.18 (12), p.2605

2017

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Structural Fuzziness of the RNA-Organizing Protein SERF Determines a Toxic Gain-of-interaction

Journal of molecular biology, 2020-02, Vol.432 (4), p.930-951

2020

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Increased Aggregation Tendency of Alpha-Synuclein in a Fully Disordered Protein Complex

Journal of molecular biology, 2019-06, Vol.431 (14), p.2581-2598

2019

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Interfering with the CCL2–glycosaminoglycan axis as a potential approach to modulate neuroinflammation

Neuroscience letters, 2016-07, Vol.626, p.164-173

2016

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CXCL9-Derived Peptides Differentially Inhibit Neutrophil Migration In Vivo through Interference with Glycosaminoglycan Interactions

Frontiers in immunology, 2017-05, Vol.8, p.530-530

2017

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Affinity and Specificity for Binding to Glycosaminoglycans Can Be Tuned by Adapting Peptide Length and Sequence

International journal of molecular sciences, 2021-12, Vol.23 (1), p.447

2021

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Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo

Bioscience reports, 2013-09, Vol.33 (5), p.e00068

2013

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Anti‐inflammatory effects of the GAG‐binding CXCL9(74‐103) peptide in dinitrofluorobenzene‐induced contact hypersensitivity in mice

Clinical and experimental allergy, 2018-10, Vol.48 (10), p.1333-1344

2018

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Cytokines and Chemokines in SARS-CoV-2 Infections-Therapeutic Strategies Targeting Cytokine Storm

Therapeutic strategies to target microbial protein-glycosaminoglycan interactions

The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis

Isolation and Characterization of Heparan Sulfate from Human Lung Tissues

Single domain shark VNAR antibodies neutralize SARS‐CoV‐2 infection in vitro

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

A combinatorial approach to biophysically characterise chemokine-glycan binding affinities for drug development

A New Monocyte Chemotactic Protein-1/Chemokine CC Motif Ligand-2 Competitor Limiting Neointima Formation and Myocardial Ischemia/Reperfusion Injury in Mice

Chemokine Binding to Tenascin-C Influences Chemokine-Induced Immune Cell Migration

Molecular dynamics simulations of the chemokine CCL2 in complex with pull down-derived heparan sulfate hexasaccharides

Exploring the glycosaminoglycan-protein interaction network by glycan-mediated pull-down proteomics

The Molecular Chaperone Hsp90 Modulates Intermediate Steps of Amyloid Assembly of the Parkinson-related Protein α-Synuclein

The Positively Charged COOH-terminal Glycosaminoglycan-binding CXCL9(74–103) Peptide Inhibits CXCL8-induced Neutrophil Extravasation and Monosodium Urate Crystal-induced Gout in Mice

Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2

Enoxaparin and Pentosan Polysulfate Bind to the SARS-CoV-2 Spike Protein and Human ACE2 Receptor, Inhibiting Vero Cell Infection

Novel Anti-Inflammatory Peptides Based on Chemokine-Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis

Soluble syndecan-3 binds chemokines, reduces leukocyte migration in vitro and ameliorates disease severity in models of rheumatoid arthritis

Glycosaminoglycan-Mediated Downstream Signaling of CXCL8 Binding to Endothelial Cells

Structural Fuzziness of the RNA-Organizing Protein SERF Determines a Toxic Gain-of-interaction

Increased Aggregation Tendency of Alpha-Synuclein in a Fully Disordered Protein Complex

Interfering with the CCL2–glycosaminoglycan axis as a potential approach to modulate neuroinflammation

CXCL9-Derived Peptides Differentially Inhibit Neutrophil Migration In Vivo through Interference with Glycosaminoglycan Interactions

Affinity and Specificity for Binding to Glycosaminoglycans Can Be Tuned by Adapting Peptide Length and Sequence

Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo

Anti‐inflammatory effects of the GAG‐binding CXCL9(74‐103) peptide in dinitrofluorobenzene‐induced contact hypersensitivity in mice

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