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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature cell biology, 2011-02, Vol.13 (2), p.132-141

2011

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ULK1, mammalian target of rapamycin, and mitochondria: linking nutrient availability and autophagy

Antioxidants & redox signaling, 2011-05, Vol.14 (10), p.1953-1958

Kundu, Mondira

2011

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Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

Nature communications, 2017-09, Vol.8 (1), p.548-13, Article 548

2017

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An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

The Journal of clinical investigation, 2019-02, Vol.129 (2), p.802-819

2019

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Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

PLoS genetics, 2015-02, Vol.11 (2), p.e1004987

2015

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ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

Molecular biology of the cell, 2009-04, Vol.20 (7), p.1992-2003

2009

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6016), p.456-461

2011

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Premature Physiologic Aging as a Paradigm for Understanding Increased Risk of Adverse Health Across the Lifespan of Survivors of Childhood Cancer

Journal of clinical oncology, 2018-07, Vol.36 (21), p.2206-2215

2018

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Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Nature immunology, 2013-05, Vol.14 (5), p.480-488

2013

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Ulk1-mediated autophagy plays an essential role in mitochondrial remodeling and functional regeneration of skeletal muscle

American Journal of Physiology: Cell Physiology, 2017-06, Vol.312 (6), p.C724-C732

2017

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The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis

Molecular cell, 2016-05, Vol.62 (4), p.491-506

2016

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Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

Blood, 2008-08, Vol.112 (4), p.1493-1502

2008

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AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival

Cell reports (Cambridge), 2020-09, Vol.32 (9), p.108092-108092, Article 108092

2020

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The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway

Autophagy, 2018-05, Vol.14 (5), p.796-811

2018

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NIX is required for programmed mitochondrial clearance during reticulocyte maturation

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (49), p.19500-19505

2007

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Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop

Autophagy, 2011-07, Vol.7 (7), p.696-706

2011

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ER-to-Golgi Trafficking and Its Implication in Neurological Diseases

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.408

2020

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Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation

Blood, 2009-07, Vol.114 (1), p.157-164

2009

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The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

Nature communications, 2017-09, Vol.8 (1), p.571-14, Article 571

2017

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Physiological functions of ULK1/2

Journal of molecular biology, 2024-08, Vol.436 (15), p.168472, Article 168472

2024

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Canonical and noncanonical functions of ULK/Atg1

Current opinion in cell biology, 2017-04, Vol.45, p.47-54

2017

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Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle

Frontiers in physiology, 2021-09, Vol.12, p.732308-732308

2021

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Lnk constrains myeloproliferative diseases in mice

The Journal of clinical investigation, 2010-06, Vol.120 (6), p.2058-2069

2010

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Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice

Blood, 2015-01, Vol.125 (1), p.162-174

2015

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Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress

International journal of molecular sciences, 2020-08, Vol.21 (17), p.6130

2020

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

ULK1, mammalian target of rapamycin, and mitochondria: linking nutrient availability and autophagy

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Premature Physiologic Aging as a Paradigm for Understanding Increased Risk of Adverse Health Across the Lifespan of Survivors of Childhood Cancer

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Ulk1-mediated autophagy plays an essential role in mitochondrial remodeling and functional regeneration of skeletal muscle

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival

The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway

NIX is required for programmed mitochondrial clearance during reticulocyte maturation

Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop

ER-to-Golgi Trafficking and Its Implication in Neurological Diseases

Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

Physiological functions of ULK1/2

Canonical and noncanonical functions of ULK/Atg1

Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle

Lnk constrains myeloproliferative diseases in mice

Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice

Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress

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