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Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets

Platelets (Edinburgh), 2022-11, Vol.33 (8), p.1301-1306

2022

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TULA-Family Regulators of Platelet Activation

International journal of molecular sciences, 2022-11, Vol.23 (23), p.14910

2022

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Role of Protein Kinase C-delta in regulating platelet activation and platelet-leukocyte interaction during sepsis

PloS one, 2018-04, Vol.13 (4), p.e0195379

2018

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MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression

PloS one, 2014-07, Vol.9 (7), p.e102259-e102259

2014

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LPS-induced systemic inflammation is more severe in P2Y12 null mice

Journal of leukocyte biology, 2014-02, Vol.95 (2), p.313-323

2014

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Protease-activated receptor 4 causes Akt phosphorylation independently of PI3 kinase pathways

Platelets (Edinburgh), 2021-08, Vol.32 (6), p.832-837

2021

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Distinct Pathways Regulate Syk Protein Activation Downstream of Immune Tyrosine Activation Motif (ITAM) and hemITAM Receptors in Platelets

The Journal of biological chemistry, 2015-05, Vol.290 (18), p.11557-11568

2015

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Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways

Biochemical journal, 2010-07, Vol.429 (2), p.369-377

2010

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D121 Located within the DRY Motif of P2Y12 Is Essential for P2Y12-Mediated Platelet Function

International journal of molecular sciences, 2022-10, Vol.23 (19), p.11519

2022

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Interleukin-17A Promotes Aortic Endothelial Cell Activation via Transcriptionally and Post-translationally Activating p38 Mitogen-activated Protein Kinase (MAPK) Pathway

The Journal of biological chemistry, 2016-03, Vol.291 (10), p.4939-4954

2016

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Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets

Platelets (Edinburgh), 2024-12, Vol.35 (1), p.2369766

2024

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Platelet Microparticles Enriched in miR-223 Reduce ICAM-1-Dependent Vascular Inflammation in Septic Conditions

Frontiers in physiology, 2021-05, Vol.12, p.658524-658524

2021

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PKC-epsilon deficiency alters progenitor cell populations in favor of megakaryopoiesis

PloS one, 2017-08, Vol.12 (8), p.e0182867-e0182867

2017

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PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses

Thrombosis and haemostasis, 2014, Vol.111 (3), p.508

2014

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Reduced miR-26b Expression in Megakaryocytes and Platelets Contributes to Elevated Level of Platelet Activation Status in Sepsis

International journal of molecular sciences, 2020-01, Vol.21 (3), p.866

2020

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Biochemical characterization of spleen tyrosine kinase (SYK) isoforms in platelets

Platelets (Edinburgh), 2023-12, Vol.34 (1), p.2249549-2249549

2023

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The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets

Biochemical journal, 2015-07, Vol.469 (2), p.199-210

2015

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Aromatic Interactions Promote Self-Association of Collagen Triple-Helical Peptides to Higher-Order Structures

Biochemistry (Easton), 2009-08, Vol.48 (33), p.7959-7968

2009

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Sex-related differences in the response of anti-platelet drug therapies targeting purinergic signaling pathways in sepsis

Frontiers in immunology, 2022-11, Vol.13, p.1015577

2022

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Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets

Biochemical journal, 2007-06, Vol.404 (2), p.299-308

2007

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Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation-Early Secretomes may Serve as Drivers for Trained Immunity

Frontiers in immunology, 2022-03, Vol.13, p.858256-858256

2022

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Akt Activation in Platelets Depends on Gi Signaling Pathways

The Journal of biological chemistry, 2004-02, Vol.279 (6), p.4186-4195

2004

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Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization

Blood, 2015-05, Vol.125 (19), p.2995-3005

2015

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Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets

Blood, 2015-01, Vol.125 (1), p.175-184

2015

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Coactivation of Two Different G Protein-Coupled Receptors is Essential for ADP-Induced Platelet Aggregation

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (14), p.8070-8074

1998

Volltextzugriff (PDF)

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Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets

TULA-Family Regulators of Platelet Activation

Role of Protein Kinase C-delta in regulating platelet activation and platelet-leukocyte interaction during sepsis

MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression

LPS-induced systemic inflammation is more severe in P2Y12 null mice

Protease-activated receptor 4 causes Akt phosphorylation independently of PI3 kinase pathways

Distinct Pathways Regulate Syk Protein Activation Downstream of Immune Tyrosine Activation Motif (ITAM) and hemITAM Receptors in Platelets

Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways

D121 Located within the DRY Motif of P2Y12 Is Essential for P2Y12-Mediated Platelet Function

Interleukin-17A Promotes Aortic Endothelial Cell Activation via Transcriptionally and Post-translationally Activating p38 Mitogen-activated Protein Kinase (MAPK) Pathway

Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets

Platelet Microparticles Enriched in miR-223 Reduce ICAM-1-Dependent Vascular Inflammation in Septic Conditions

PKC-epsilon deficiency alters progenitor cell populations in favor of megakaryopoiesis

PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses

Reduced miR-26b Expression in Megakaryocytes and Platelets Contributes to Elevated Level of Platelet Activation Status in Sepsis

Biochemical characterization of spleen tyrosine kinase (SYK) isoforms in platelets

The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets

Aromatic Interactions Promote Self-Association of Collagen Triple-Helical Peptides to Higher-Order Structures

Sex-related differences in the response of anti-platelet drug therapies targeting purinergic signaling pathways in sepsis

Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets

Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation-Early Secretomes may Serve as Drivers for Trained Immunity

Akt Activation in Platelets Depends on Gi Signaling Pathways

Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization

Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets

Coactivation of Two Different G Protein-Coupled Receptors is Essential for ADP-Induced Platelet Aggregation

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