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4-Pyridone derivatives as new inhibitors of bacterial enoyl-ACP reductase FabI

Bioorganic & medicinal chemistry, 2007-01, Vol.15 (2), p.1106-1116

2007

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Characterization of compound A, a novel lincomycin derivative active against methicillin-resistant Staphylococcus aureus

Journal of antibiotics, 2021-02, Vol.74 (2), p.124-132

2021

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Discovery of 4-Pyridone derivatives as specific inhibitors of enoyl-acyl carrier protein reductase (FabI) with antibacterial activity against Staphylococcus aureus

Journal of antibiotics, 2007-02, Vol.60 (2), p.123-128

2007

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Discovery of 4-Pyridone Derivatives as Specific Inhibitors of Enoyl-Acyl Carrier Protein Reductase (Fabl) with Antibacterial Activity Against Staphylococcus aureus

ChemInform, 2007-08, Vol.38 (34), p.no-no

2007

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Generation of nitric oxide and superoxide during reperfusion after focal cerebral ischemia in rats

American Journal of Physiology: Cell Physiology, 1996-03, Vol.270 (3), p.C748-C752

1996

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Generation of nitric oxide and superoxide during reperfusion after focal cerebral ischemia in rats

American Journal of Physiology: Cell Physiology, 1996-03, Vol.39 (3), p.C748-C752

1996

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Increase in jugular levels of polymorphonuclear neutrophil elastase in patients with acute cerebral infarction

Neurological research (New York), 1998-07, Vol.20 (5), p.397-402

1998

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Increase in plasma nitric oxide end products following rat cortical injury

Neuroscience letters, 1995-07, Vol.194 (1), p.124-126

1995

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ME3183, a novel phosphodiesterase-4 inhibitor, exhibits potent anti-inflammatory effects and is well tolerated in a non-clinical study

European journal of pharmacology, 2024-01, Vol.962, p.176202-176202, Article 176202

2024

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A Novel Synthesis of 2,3-Disubstituted-4-pyridones from 4-Methoxypyridine

ChemInform, 2006-12, Vol.37 (51), p.no-no

2006

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Surgical Outcome of Bilateral Spinal Decompression through Unilateral Laminotomy for Lumbar Canal Stenosis associated with Long-Term Hemodialysis

Spinal Surgery, 2004, Vol.18(3), pp.189-195

2004

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Surgical Outcome of Bilateral Spinal Decompression through Unilateral Laminotomy for Lumbar Canal Stenosis associated with Long-Term Hemodialysis

Sekizui geka, 2004, Vol.18 (3), p.189-195

2004

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Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines

Journal of antibiotics, 2016-06, Vol.69 (6), p.440-445

2016

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Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives

Journal of antibiotics, 2017-05, Vol.70 (5), p.655-663

2017

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Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety

Journal of antibiotics, 2018-01, Vol.71 (1), p.104-112

2018

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Synthesis and antibacterial activity of novel lincomycin derivatives. IV. Optimization of an N-6 substituent

Journal of antibiotics, 2017-12, Vol.70 (12), p.1112-1121

2017

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Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification

Journal of antibiotics, 2016-05, Vol.69 (5), p.368-380

2016

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Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA

Journal of antibiotics, 2016-06, Vol.69 (6), p.428-439

2016

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Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs

Journal of antibiotics, 2017-01, Vol.70 (1), p.52-64

2017

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Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities

Journal of antibiotics, 2017-08, Vol.70 (8), p.888-906

2017

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Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities

Journal of antibiotics, 2013-03, Vol.66 (3), p.195-198

2013

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4-Pyridone derivatives as new inhibitors of bacterial enoyl-ACP reductase FabI

Characterization of compound A, a novel lincomycin derivative active against methicillin-resistant Staphylococcus aureus

Discovery of 4-Pyridone derivatives as specific inhibitors of enoyl-acyl carrier protein reductase (FabI) with antibacterial activity against Staphylococcus aureus

Discovery of 4-Pyridone Derivatives as Specific Inhibitors of Enoyl-Acyl Carrier Protein Reductase (Fabl) with Antibacterial Activity Against Staphylococcus aureus

Generation of nitric oxide and superoxide during reperfusion after focal cerebral ischemia in rats

Generation of nitric oxide and superoxide during reperfusion after focal cerebral ischemia in rats

Increase in jugular levels of polymorphonuclear neutrophil elastase in patients with acute cerebral infarction

Increase in plasma nitric oxide end products following rat cortical injury

ME3183, a novel phosphodiesterase-4 inhibitor, exhibits potent anti-inflammatory effects and is well tolerated in a non-clinical study

A Novel Synthesis of 2,3-Disubstituted-4-pyridones from 4-Methoxypyridine

Surgical Outcome of Bilateral Spinal Decompression through Unilateral Laminotomy for Lumbar Canal Stenosis associated with Long-Term Hemodialysis

Surgical Outcome of Bilateral Spinal Decompression through Unilateral Laminotomy for Lumbar Canal Stenosis associated with Long-Term Hemodialysis

Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines

Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives

Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety

Synthesis and antibacterial activity of novel lincomycin derivatives. IV. Optimization of an N-6 substituent

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA

Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities

Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities

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