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Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors

Molecular cancer therapeutics, 2018-07, Vol.17 (7), p.1504-1514

2018

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Alternative Lengthening of Telomeres in Pediatric High-Grade Glioma and Therapeutic Implications

Cancers, 2023-06, Vol.15 (12), p.3070

2023

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Limitations of radiosensitization by direct telomerase inhibition to treat high-risk medulloblastoma

Frontiers in oncology, 2023-01, Vol.13, p.1104670-1104670

2023

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Distinct metabolic effects following short-term exposure of different high-fat diets in male and female mice

Endocrine Journal, 2014, Vol.61(5), pp.457-470

2014

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Estradiol regulates insulin signaling and inflammation in adipose tissue

Hormone molecular biology and clinical investigation, 2014-02, Vol.17 (2), p.99-107

2014

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Preclinical pediatric brain tumor models for immunotherapy: Hurdles and a way forward

Neuro-oncology (Charlottesville, Va.), 2024-02, Vol.26 (2), p.226-235

2024

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Diffuse Intrinsic Pontine Glioma Cells Are Vulnerable to Mitotic Abnormalities Associated with BMI-1 Modulation

Molecular cancer research, 2020-11, Vol.18 (11), p.1711-1723

2020

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Central expression and anorectic effect of brain-derived neurotrophic factor are regulated by circulating estradiol levels

Hormones and behavior, 2013-03, Vol.63 (3), p.533-542

2013

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BMI-1 is a potential therapeutic target in diffuse intrinsic pontine glioma

Oncotarget, 2017-09, Vol.8 (38), p.62962-62975

2017

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Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

Acta neuropathologica communications, 2016-01, Vol.4 (1), p.1-1, Article 1

2016

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A pilot radiogenomic study of DIPG reveals distinct subgroups with unique clinical trajectories and therapeutic targets

Acta neuropathologica communications, 2021-01, Vol.9 (1), p.14-14, Article 14

2021

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Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report

Neuro-oncology advances, 2022-01, Vol.4 (1), p.vdac055-vdac055

2022

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G Protein-Coupled Estrogen Receptor in Energy Homeostasis and Obesity Pathogenesis

Progress in Molecular Biology and Translational Science, 2013, Vol.114, p.193-250

2013

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DIPG-06. PRECLINICAL EVALUATION OF A NOVEL ACVR1 INHIBITOR IN DIFFUSE INTRINSIC PONTINE GLIOMAS

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i13-i14

2023

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DIPG-12. Induced mitotic abnormalities associated with BMI-1 modulation sensitize diffuse intrinsic pontine glioma cells to ionizing radiation

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i20-i20

2022

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DIPG-05. EVALUATION OF TELOMERE-MODIFYING COMPOUND THIO AS A RADIOSENSITIZER AND IMMUNOMODULATOR TO TREAT DIPG

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i13-i13

2023

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DIPG-07. ROBUST CGAS-STING PATHWAY MEDIATED-INDUCTION OF ANTITUMOR ADAPTIVE IMMUNE RESPONSE: A POTENTIAL FOR DMG IMMUNOTHERAPY

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i14-i14

2023

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Erratum: Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

Acta neuropathologica communications, 2016-02, Vol.4 (12), p.13-13, Article 13

2016

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DIPG-13. Immune profiling by RNA-seq deconvolution and single-cell sequencing reveal myeloid cell enrichment in DIPG tumor microenvironment

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i20-i20

2022

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Abstract 5108: Immunomodulatory and anti-tumor effect of radiation and induced telomere damage to treat pediatric high-grade gliomas

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5108-5108

2024

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Abstract 508: Determining the nuclear and cytoplasmic function of BMI-1 in diffuse intrinsic pontine glioma during M phase

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.508-508

2024

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THER-10. TELOMERE TARGETING BASED-THERAPIES TO TREAT THERAPY-RESISTANT PEDIATRIC BRAIN TUMORS

Neuro-oncology (Charlottesville, Va.), 2019-04, Vol.21 (Supplement_2), p.ii116-ii116

2019

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DIPG-21. INDUCTION OF MITOTIC ABNORMALITIES AND BMI-1 MODULATION TO TREAT DIFFUSE INTRINSIC PONTINE GLIOMA

Neuro-oncology (Charlottesville, Va.), 2020-12, Vol.22 (Supplement_3), p.iii291-iii291

2020

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DIPG-16. Evaluation of myeloid component of DIPG microenvironment

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i21-i21

2022

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DIPG-11. DIPGs show robust MHC class I expression but low lymphoid and high myeloid infiltration partly reversible by DNA methyltransferase inhibition

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i20-i20

2022

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Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors

Alternative Lengthening of Telomeres in Pediatric High-Grade Glioma and Therapeutic Implications

Limitations of radiosensitization by direct telomerase inhibition to treat high-risk medulloblastoma

Distinct metabolic effects following short-term exposure of different high-fat diets in male and female mice

Estradiol regulates insulin signaling and inflammation in adipose tissue

Preclinical pediatric brain tumor models for immunotherapy: Hurdles and a way forward

Diffuse Intrinsic Pontine Glioma Cells Are Vulnerable to Mitotic Abnormalities Associated with BMI-1 Modulation

Central expression and anorectic effect of brain-derived neurotrophic factor are regulated by circulating estradiol levels

BMI-1 is a potential therapeutic target in diffuse intrinsic pontine glioma

Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

A pilot radiogenomic study of DIPG reveals distinct subgroups with unique clinical trajectories and therapeutic targets

Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report

G Protein-Coupled Estrogen Receptor in Energy Homeostasis and Obesity Pathogenesis

DIPG-06. PRECLINICAL EVALUATION OF A NOVEL ACVR1 INHIBITOR IN DIFFUSE INTRINSIC PONTINE GLIOMAS

DIPG-12. Induced mitotic abnormalities associated with BMI-1 modulation sensitize diffuse intrinsic pontine glioma cells to ionizing radiation

DIPG-05. EVALUATION OF TELOMERE-MODIFYING COMPOUND THIO AS A RADIOSENSITIZER AND IMMUNOMODULATOR TO TREAT DIPG

DIPG-07. ROBUST CGAS-STING PATHWAY MEDIATED-INDUCTION OF ANTITUMOR ADAPTIVE IMMUNE RESPONSE: A POTENTIAL FOR DMG IMMUNOTHERAPY

Erratum: Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

DIPG-13. Immune profiling by RNA-seq deconvolution and single-cell sequencing reveal myeloid cell enrichment in DIPG tumor microenvironment

Abstract 5108: Immunomodulatory and anti-tumor effect of radiation and induced telomere damage to treat pediatric high-grade gliomas

Abstract 508: Determining the nuclear and cytoplasmic function of BMI-1 in diffuse intrinsic pontine glioma during M phase

THER-10. TELOMERE TARGETING BASED-THERAPIES TO TREAT THERAPY-RESISTANT PEDIATRIC BRAIN TUMORS

DIPG-21. INDUCTION OF MITOTIC ABNORMALITIES AND BMI-1 MODULATION TO TREAT DIFFUSE INTRINSIC PONTINE GLIOMA

DIPG-16. Evaluation of myeloid component of DIPG microenvironment

DIPG-11. DIPGs show robust MHC class I expression but low lymphoid and high myeloid infiltration partly reversible by DNA methyltransferase inhibition

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