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AMPK as a potential anticancer target - friend or foe?

Current pharmaceutical design, 2014, Vol.20 (15), p.2607-2618

2014

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AMPK Reverses the Mesenchymal Phenotype of Cancer Cells by Targeting the Akt-MDM2-Foxo3a Signaling Axis

Cancer research (Chicago, Ill.), 2014-09, Vol.74 (17), p.4783-4795

2014

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Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition

Clinical cancer research, 2021-04, Vol.27 (8), p.2352-2366

2021

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Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia

JNCI : Journal of the National Cancer Institute, 2015-12, Vol.107 (12), p.djv274-djv274

2015

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Indole-3-carbinol as a chemopreventive and anti-cancer agent

Cancer letters, 2008-04, Vol.262 (2), p.153-163

2008

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Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells

Breast cancer research and treatment, 2012-07, Vol.134 (2), p.649-659

2012

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Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines

PloS one, 2013-06, Vol.8 (6), p.e67149

2013

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Energy Restriction as an Antitumor Target of Thiazolidinediones

The Journal of biological chemistry, 2010-03, Vol.285 (13), p.9780-9791

2010

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Decoupling FcRn and tumor contributions to elevated immune checkpoint inhibitor clearance in cancer cachexia

Pharmacological research, 2024-01, Vol.199, p.107048-107048, Article 107048

2024

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Antibody Drug Clearance: An Underexplored Marker of Outcomes with Checkpoint Inhibitors

Clinical cancer research, 2024-03, Vol.30 (5), p.942-958

2024

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Inhibition of androgen/AR signaling inhibits diethylnitrosamine (DEN) induced tumour initiation and remodels liver immune cell networks

Scientific reports, 2021-02, Vol.11 (1), p.3646-16, Article 3646

2021

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Retraction: Antitumor Effects of a Novel Phenylbutyrate-based Histone Deacetylase Inhibitor, ( S )-HDAC-42, in Prostate Cancer

Clinical cancer research, 2019-05, Vol.25 (9), p.2940-2940

2019

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The elucidation of species-specific receptor pharmacology: a case study using subtype selective para - and meta -carborane estrogen receptor agonists

The Journal of pharmacology and experimental therapeutics, 2024-06, p.JPET-AR-2023-001874

2024

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Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases

Molecular pharmacology, 2011-01, Vol.79 (1), p.197-206

2011

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Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2445-2454

2010

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Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent

PloS one, 2012-10, Vol.7 (10), p.e47298

2012

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Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis

BMC cancer, 2017-01, Vol.17 (1), p.67-67, Article 67

2017

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The Neonatal Fc Receptor Is Elevated in Monocyte-Derived Immune Cells in Pancreatic Cancer

International journal of molecular sciences, 2022-06, Vol.23 (13), p.7066

2022

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Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor

EMBO molecular medicine, 2020-02, Vol.12 (2), p.e9910-n/a

2020

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The mRNA-stabilizing Factor HuR Protein Is Targeted by β-TrCP Protein for Degradation in Response to Glycolysis Inhibition

The Journal of biological chemistry, 2012-12, Vol.287 (52), p.43639-43650

2012

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Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

The Journal of biological chemistry, 2011-11, Vol.286 (45), p.39247-39258

2011

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Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae

Neoplasia (New York, N.Y.), 2015-06, Vol.17 (6), p.497-508

2015

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Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models

Molecular pharmaceutics, 2023-06, Vol.20 (6), p.3049-3059

2023

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PPARγ-independent antitumor effects of thiazolidinediones

Cancer letters, 2009-04, Vol.276 (2), p.119-124

2009

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Retraction: Sensitizing Estrogen Receptor-negative Breast Cancer Cells to Tamoxifen with OSU-03012, a Novel Celecoxib-derived Phosphoinositide-dependent Protein Kinase-1/Akt Signaling Inhibitor

Molecular cancer therapeutics, 2019-04, Vol.18 (4), p.869-869

2019

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AMPK as a potential anticancer target - friend or foe?

AMPK Reverses the Mesenchymal Phenotype of Cancer Cells by Targeting the Akt-MDM2-Foxo3a Signaling Axis

Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition

Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia

Indole-3-carbinol as a chemopreventive and anti-cancer agent

Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells

Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines

Energy Restriction as an Antitumor Target of Thiazolidinediones

Decoupling FcRn and tumor contributions to elevated immune checkpoint inhibitor clearance in cancer cachexia

Antibody Drug Clearance: An Underexplored Marker of Outcomes with Checkpoint Inhibitors

Inhibition of androgen/AR signaling inhibits diethylnitrosamine (DEN) induced tumour initiation and remodels liver immune cell networks

Retraction: Antitumor Effects of a Novel Phenylbutyrate-based Histone Deacetylase Inhibitor, ( S )-HDAC-42, in Prostate Cancer

The elucidation of species-specific receptor pharmacology: a case study using subtype selective para - and meta -carborane estrogen receptor agonists

Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases

Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent

Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis

The Neonatal Fc Receptor Is Elevated in Monocyte-Derived Immune Cells in Pancreatic Cancer

Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor

The mRNA-stabilizing Factor HuR Protein Is Targeted by β-TrCP Protein for Degradation in Response to Glycolysis Inhibition

Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae

Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models

PPARγ-independent antitumor effects of thiazolidinediones

Retraction: Sensitizing Estrogen Receptor-negative Breast Cancer Cells to Tamoxifen with OSU-03012, a Novel Celecoxib-derived Phosphoinositide-dependent Protein Kinase-1/Akt Signaling Inhibitor

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