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Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1

Pharmacogenetics and genomics, 2012-07, Vol.22 (7), p.525-537

2012

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Prostaglandin H synthase: Resolved and unresolved mechanistic issues

Archives of biochemistry and biophysics, 2010-01, Vol.493 (1), p.103-124

2010

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Heritable Thoracic Aortic Disease Genes in Sporadic Aortic Dissection

Journal of the American College of Cardiology, 2017-11, Vol.70 (21), p.2728-2730

2017

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Kinetic Isotope Effect of Prostaglandin H Synthase Exhibits Inverted Temperature Dependence

Catalysts, 2014-06, Vol.4 (2), p.174-185

2014

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Functional and structural roles of residues in the third extramembrane segment of adrenal cytochrome b561

Biochemistry (Easton), 2011-04, Vol.50 (15), p.3149

2011

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MYLK pathogenic variants aortic disease presentation, pregnancy risk, and characterization of pathogenic missense variants

Genetics in medicine, 2019-01, Vol.21 (1), p.144-151

2019

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Regulation of cyclooxygenase catalysis by hydroperoxides

Biochemical and biophysical research communications, 2005-12, Vol.338 (1), p.25-33

Kulmacz, Richard J.

2005

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COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations

Cancer causes & control, 2013-12, Vol.24 (12), p.2059-2075

2013

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Role of Asn-382 and Thr-383 in Activation and Inactivation of Human Prostaglandin H Synthase Cyclooxygenase Catalysis

The Journal of biological chemistry, 2004-02, Vol.279 (6), p.4084-4092

2004

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IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry

Carcinogenesis (New York), 2013-01, Vol.34 (1), p.79-85

2013

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Development of a bacterial system for high yield expression of fully functional adrenal cytochrome b561

Protein expression and purification, 2007-12, Vol.56 (2), p.145-152

2007

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Analysis of Hydroperoxide-Induced Tyrosyl Radicals and Lipoxygenase Activity in Aspirin-Treated Human Prostaglandin H Synthase-2

Biochemistry (Easton), 1997-02, Vol.36 (7), p.1836-1845

1997

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Phospholipid actions on PGHS-1 and -2 cyclooxygenase kinetics

Prostaglandins & other lipid mediators, 2008-03, Vol.85 (3), p.134-143

2008

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The Cyclooxygenase Reaction Mechanism

Biochemistry (Easton), 2002-12, Vol.41 (52), p.15451-15458

2002

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Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: Colon cancer family registry

Genes chromosomes & cancer, 2014-07, Vol.53 (7), p.568-578

2014

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Cyclooxygenase Competitive Inhibitors Alter Tyrosyl Radical Dynamics in Prostaglandin H Synthase-2

Biochemistry (Easton), 2009-12, Vol.48 (50), p.11902-11911

2009

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High-yield production, purification and characterization of functional human duodenal cytochrome b in an Escherichia coli system

Protein expression and purification, 2011-09, Vol.79 (1), p.115-121

2011

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Glutathione peroxidase tagSNPs: Associations with rectal cancer but not with colon cancer

Genes chromosomes & cancer, 2012-06, Vol.51 (6), p.598-605

2012

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Structural Characterization of Arachidonyl Radicals Formed by Aspirin-treated Prostaglandin H Synthase-2

The Journal of biological chemistry, 2002-10, Vol.277 (41), p.38311-38321

2002

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Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects

Journal of inorganic biochemistry, 2011-03, Vol.105 (3), p.382-390

2011

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Functional analysis of human thromboxane synthase polymorphic variants

Pharmacogenetics and genomics, 2012-09, Vol.22 (9), p.653-658

2012

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Axial Ligation and Stoichiometry of Heme Centers in Adrenal Cytochrome b561

Biochemistry (Easton), 2007-07, Vol.46 (29), p.8647-8658

2007

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Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases

The FASEB journal, 2006-06, Vol.20 (8), p.1097-1108

2006

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Comparison of the properties of prostaglandin H synthase-1 and -2

Progress in Lipid Research, 2003-09, Vol.42 (5), p.377-404

2003

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Genetic Variation in Prostaglandin E2 Synthesis and Signaling, Prostaglandin Dehydrogenase, and the Risk of Colorectal Adenoma

Cancer epidemiology, biomarkers & prevention, 2010-02, Vol.19 (2), p.547-557

2010

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Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1

Prostaglandin H synthase: Resolved and unresolved mechanistic issues

Heritable Thoracic Aortic Disease Genes in Sporadic Aortic Dissection

Kinetic Isotope Effect of Prostaglandin H Synthase Exhibits Inverted Temperature Dependence

Functional and structural roles of residues in the third extramembrane segment of adrenal cytochrome b561

MYLK pathogenic variants aortic disease presentation, pregnancy risk, and characterization of pathogenic missense variants

Regulation of cyclooxygenase catalysis by hydroperoxides

COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations

Role of Asn-382 and Thr-383 in Activation and Inactivation of Human Prostaglandin H Synthase Cyclooxygenase Catalysis

IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry

Development of a bacterial system for high yield expression of fully functional adrenal cytochrome b561

Analysis of Hydroperoxide-Induced Tyrosyl Radicals and Lipoxygenase Activity in Aspirin-Treated Human Prostaglandin H Synthase-2

Phospholipid actions on PGHS-1 and -2 cyclooxygenase kinetics

The Cyclooxygenase Reaction Mechanism

Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: Colon cancer family registry

Cyclooxygenase Competitive Inhibitors Alter Tyrosyl Radical Dynamics in Prostaglandin H Synthase-2

High-yield production, purification and characterization of functional human duodenal cytochrome b in an Escherichia coli system

Glutathione peroxidase tagSNPs: Associations with rectal cancer but not with colon cancer

Structural Characterization of Arachidonyl Radicals Formed by Aspirin-treated Prostaglandin H Synthase-2

Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects

Functional analysis of human thromboxane synthase polymorphic variants

Axial Ligation and Stoichiometry of Heme Centers in Adrenal Cytochrome b561

Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases

Comparison of the properties of prostaglandin H synthase-1 and -2

Genetic Variation in Prostaglandin E2 Synthesis and Signaling, Prostaglandin Dehydrogenase, and the Risk of Colorectal Adenoma

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