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Caenorhabditis elegans in anthelmintic research – Old model, new perspectives

International journal for parasitology -- drugs and drug resistance, 2020-12, Vol.14, p.237-248

2020

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Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential

Nature communications, 2023-03, Vol.14 (1), p.1816-1816, Article 1816

2023

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Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel

PLoS pathogens, 2019-09, Vol.15 (9), p.e1008041-e1008041

2019

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Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009682-e1009682

2021

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Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

Cell reports (Cambridge), 2021-01, Vol.34 (2), p.108621-108621, Article 108621

2021

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Dirofilaria immitis Microfilariae and Third-Stage Larvae Induce Canine NETosis Resulting in Different Types of Neutrophil Extracellular Traps

Frontiers in immunology, 2018-05, Vol.9, p.968-968

2018

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Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis

PLoS pathogens, 2021-06, Vol.17 (6), p.e1009601-e1009601

2021

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Efficacy evaluation of anthelmintic products against an infection with the canine hookworm (Ancylostoma caninum) isolate Worthy 4.1F3P in dogs

International journal for parasitology -- drugs and drug resistance, 2020-08, Vol.13, p.22-27

2020

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Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans

International journal for parasitology -- drugs and drug resistance, 2021-08, Vol.16, p.174-187

2021

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Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside

International journal for parasitology -- drugs and drug resistance, 2021-12, Vol.17, p.27-35

2021

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Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite

International journal for parasitology -- drugs and drug resistance, 2019-08, Vol.10, p.45-50

2019

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Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside

PLoS neglected tropical diseases, 2014-12, Vol.8 (12), p.e3401-e3401

2014

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Efficacy of cyclooctadepsipeptides and aminophenylamidines against larval, immature and mature adult stages of a parasitologically characterized trichurosis model in mice

PLoS neglected tropical diseases, 2014-02, Vol.8 (2), p.e2698

2014

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Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (34), p.e2111932119-e2111932119

2022

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Reprogramming the Biosynthesis of Cyclodepsipeptide Synthetases to Obtain New Enniatins and Beauvericins

Chembiochem : a European journal of chemical biology, 2016-02, Vol.17 (4), p.283-287

2016

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Cover Picture: Reprogramming the Biosynthesis of Cyclodepsipeptide Synthetases to Obtain New Enniatins and Beauvericins (ChemBioChem 4/2016)

Chembiochem : a European journal of chemical biology, 2016-02, Vol.17 (4), p.269-269

2016

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Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice: e2698

PLoS neglected tropical diseases, 2014-02, Vol.8 (2)

2014

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Identification of novel splice variants of the voltage- and Ca2+-dependent K+-channel SLO-1 of Trichuris muris

Molecular and biochemical parasitology, 2015-01, Vol.199 (1-2), p.5-8

2015

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Periodicity of Dirofilaria immitis in Longterm Infections

Parasitology research (1987), 2017-08, Vol.116 (Suppl 1), p.75-80

2017

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In vivo efficacy of the anthelmintic tribendimidine against the cestode Hymenolepis microstoma in a controlled laboratory trial

Acta tropica, 2012-08, Vol.123 (2), p.78-84

2012

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In vivo efficacy of PF1022A and nicotinic acetylcholine receptor agonists alone and in combination against Nippostrongylus brasiliensis

Parasitology, 2013-09, Vol.140 (10), p.1252-1265

2013

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Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release

Communications biology, 2022-08, Vol.5 (1), p.865-865, Article 865

2022

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In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis

Parasitology research (1987), 2013, Vol.112 (1), p.335-345

2013

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Characterization of the [Ca.sup.2+]-gated and voltage-dependent [K.sup.+]-channel Slo-1 of nematodes and its interaction with emodepside

PLoS neglected tropical diseases, 2014-12, Vol.8 (12)

2014

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Characterization of the Ca 2+ -Gated and Voltage-Dependent K + -Channel Slo-1 of Nematodes and Its Interaction with Emodepside: e3401

PLoS neglected tropical diseases, 2014-12, Vol.8 (12)

2014

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Caenorhabditis elegans in anthelmintic research – Old model, new perspectives

Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential

Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel

Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration

Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

Dirofilaria immitis Microfilariae and Third-Stage Larvae Induce Canine NETosis Resulting in Different Types of Neutrophil Extracellular Traps

Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis

Efficacy evaluation of anthelmintic products against an infection with the canine hookworm (Ancylostoma caninum) isolate Worthy 4.1F3P in dogs

Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans

Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside

Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite

Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside

Efficacy of cyclooctadepsipeptides and aminophenylamidines against larval, immature and mature adult stages of a parasitologically characterized trichurosis model in mice

Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi

Reprogramming the Biosynthesis of Cyclodepsipeptide Synthetases to Obtain New Enniatins and Beauvericins

Cover Picture: Reprogramming the Biosynthesis of Cyclodepsipeptide Synthetases to Obtain New Enniatins and Beauvericins (ChemBioChem 4/2016)

Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice: e2698

Identification of novel splice variants of the voltage- and Ca2+-dependent K+-channel SLO-1 of Trichuris muris

Periodicity of Dirofilaria immitis in Longterm Infections

In vivo efficacy of the anthelmintic tribendimidine against the cestode Hymenolepis microstoma in a controlled laboratory trial

In vivo efficacy of PF1022A and nicotinic acetylcholine receptor agonists alone and in combination against Nippostrongylus brasiliensis

Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release

In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis

Characterization of the [Ca.sup.2+]-gated and voltage-dependent [K.sup.+]-channel Slo-1 of nematodes and its interaction with emodepside

Characterization of the Ca 2+ -Gated and Voltage-Dependent K + -Channel Slo-1 of Nematodes and Its Interaction with Emodepside: e3401

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