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Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

Nature reviews. Molecular cell biology, 2012-08, Vol.13 (8), p.508-523

2012

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Mechanisms of regulation and diversification of deubiquitylating enzyme function

Journal of cell science, 2017-06, Vol.130 (12), p.1997-2006

2017

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Linking K29-Ub chains to biology

Nature chemical biology, 2021-08, Vol.17 (8), p.843-844

2021

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Chemical biology tools to study Deubiquitinases and Ubl proteases

Seminars in cell & developmental biology, 2022-12, Vol.132, p.86-96

2022

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MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

Molecular cell, 2016-07, Vol.63 (1), p.146-155

2016

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Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Molecular cell, 2018-04, Vol.70 (1), p.150-164.e6

2018

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OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

Cell, 2013-07, Vol.154 (1), p.169-184

2013

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K29-Selective Ubiquitin Binding Domain Reveals Structural Basis of Specificity and Heterotypic Nature of K29 Polyubiquitin

Molecular cell, 2015-04, Vol.58 (1), p.83-94

2015

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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

PloS one, 2021-07, Vol.16 (7), p.e0253364

2021

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Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

Nature (London), 2016-10, Vol.538 (7625), p.402-405

2016

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Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2

Molecular cell, 2021-10, Vol.81 (20), p.4176-4190.e6

2021

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Regulation of A20 and other OTU deubiquitinases by reversible oxidation

Nature communications, 2013, Vol.4 (1), p.1569-1569, Article 1569

2013

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Autoinhibition and adapter function of Syk

Immunological reviews, 2009-11, Vol.232 (1), p.286-299

2009

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Expansion of DUB functionality generated by alternative isoforms - USP35, a case study

Journal of cell science, 2018-05, Vol.131 (10), p.jcs212753-jcs212753

2018

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Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity

Cell reports (Cambridge), 2016-07, Vol.16 (4), p.1180-1193

2016

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Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs

Cell chemical biology, 2016-04, Vol.23 (4), p.432-434

Kulathu, Yogesh

2016

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Deubiquitinases: From mechanisms to their inhibition by small molecules

Molecular cell, 2022-01, Vol.82 (1), p.15-29

2022

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A guide to UFMylation, an emerging posttranslational modification

The FEBS journal, 2023-11, Vol.290 (21), p.5040-5056

2023

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Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations

Biochemical journal, 2015-04, Vol.467 (2), p.345-352

2015

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Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells

The Journal of experimental medicine, 2006-12, Vol.203 (13), p.2829-2840

2006

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Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

Nature structural & molecular biology, 2009-12, Vol.16 (12), p.1328-1330

2009

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OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

Cell, 2013-06, Vol.153 (6), p.1312-1326

2013

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A leucine zipper in the N terminus confers membrane association to SLP-65

Nature immunology, 2005-02, Vol.6 (2), p.204-210

2005

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Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation

Structure (London), 2021-03, Vol.29 (3), p.238-251.e4

2021

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A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation

The EMBO journal, 2022-11, Vol.41 (21), p.e111015-n/a

2022

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Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

Mechanisms of regulation and diversification of deubiquitylating enzyme function

Linking K29-Ub chains to biology

Chemical biology tools to study Deubiquitinases and Ubl proteases

MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

K29-Selective Ubiquitin Binding Domain Reveals Structural Basis of Specificity and Heterotypic Nature of K29 Polyubiquitin

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

Autoinhibition and adapter function of Syk

Expansion of DUB functionality generated by alternative isoforms - USP35, a case study

Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity

Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs

Deubiquitinases: From mechanisms to their inhibition by small molecules

A guide to UFMylation, an emerging posttranslational modification

Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations

Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

A leucine zipper in the N terminus confers membrane association to SLP-65

Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation

A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation

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