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BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Antitumor Activity In Vivo in Hematologic Malignancies

Clinical cancer research, 2013-01, Vol.19 (2), p.357-366

2013

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In vitro and In vivo Characterization of MDX-1401 for Therapy of Malignant Lymphoma

Clinical cancer research, 2009-05, Vol.15 (10), p.3376-3383

2009

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Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway

Oncotarget, 2016-01, Vol.7 (3), p.2809-2822

2016

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nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies

Cancer Immunology, Immunotherapy, 2010-02, Vol.59 (2), p.257-265

2010

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A Guanine Nucleotide Exchange Factor-independent Function of Vav1 in Transcriptional Activation

The Journal of biological chemistry, 2000-01, Vol.275 (3), p.2185-2190

2000

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Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization

The Journal of immunology (1950), 2003-07, Vol.171 (2), p.860-866

2003

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Phase 1b study of GS-3583, a novel FLT3 agonist Fc fusion protein, in patients with advanced solid tumors

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.2566-2566

2022

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W1170 CXCL10 Expression and Biological Activities in Inflammatory Bowel Disease

Gastroenterology (New York, N.Y. 1943), 2008, Vol.134 (4), p.A-648-A-648

2008

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Phase 1b dose escalation study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GS-3583, a FLT3 agonist Fc fusion protein, in patients with advanced solid tumors

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.TPS3147-TPS3147

2021

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GS-3583, a novel FLT3 agonist Fc fusion protein, to expand conventional dendritic cells in healthy volunteers

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.2559-2559

2021

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Assembly and regulation of the CD40 receptor complex in human B cells

The Journal of experimental medicine, 1997-07, Vol.186 (2), p.337-342

1997

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Uncoupling of Nonreceptor Tyrosine Kinases from PLC-γ1 in an SLP-76- Deficient T Cell

Science (American Association for the Advancement of Science), 1998-07, Vol.281 (5375), p.413-416

1998

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BMS-936564 (Anti-CXCR4 Antibody) Induces Specific Leukemia Cell Mobilization and Objective Clinical Responses In CLL Patients Treated Under a Phase I Clinical Trial

Blood, 2013-11, Vol.122 (21), p.4190-4190

2013

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A Novel Activating Mutation Of CXCR4 Plays a Crucial Role In Waldenstrom Macroglobulinemia Biology

Blood, 2013-11, Vol.122 (21), p.272-272

2013

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CXCR4 Monoclonal Antibody, BMS-936564 (MDX-1338), Modulates Epithelial to Mesenchymal Transition (EMT) in Multiple Myeloma Cells

Blood, 2012-11, Vol.120 (21), p.4009-4009

2012

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BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Anti Tumor Activity In Vivo

Blood, 2011-11, Vol.118 (21), p.1543-1543

2011

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BMS-936564 (MDX1338): A Fully Human Anti-CXCR4 Antibody Induces Apoptosis in an in Vitro Model of Stromal – Leukemia Cell Interaction for Chronic Lymphocytic Leukemia

Blood, 2012-11, Vol.120 (21), p.2887-2887

2012

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Characterization of MDX-1401, a Human Anti-CD30 Antibody with Enhanced Effector Function, for Therapy of Malignant Lymphoma

Blood, 2008-11, Vol.112 (11), p.1580-1580

2008

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Linker for Activation of T Cells, {zeta}-Associated Protein-70, and Src Homology 2 Domain-Containing Leukocyte Protein-76 are Required for TCR-Induced Microtubule-Organizing Center Polarization

The Journal of immunology (1950), 2003-07, Vol.171 (2), p.860-866

2003

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The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp

The Journal of biological chemistry, 1993-06, Vol.268 (16), p.11479-11481

1993

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Uncoupling of nonreceptor tyrosine kinases from (PLC-gamma1) in an SLP-76--deficient T cell

Science (American Association for the Advancement of Science), 1998-07, Vol.281 (5375), p.413-416

1998

Volltextzugriff (PDF)

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma-1 tyrosine kinases from PLC-gamma-1 in an SLP-76-deficient T cell

Science (American Association for the Advancement of Science), 1998-07, Vol.281 (5375), p.413

1998

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The association of insulin-elicited phosphotyrosine proteins with src homology 2 domains

The Journal of biological chemistry, 1992-06, Vol.267 (16), p.11631-11636

1992

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Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C

The Journal of biological chemistry, 1994-06, Vol.269 (22), p.15833-15837

1994

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BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Antitumor Activity In Vivo in Hematologic Malignancies

Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody

In vitro and In vivo Characterization of MDX-1401 for Therapy of Malignant Lymphoma

Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway

nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies

A Guanine Nucleotide Exchange Factor-independent Function of Vav1 in Transcriptional Activation

Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization

Phase 1b study of GS-3583, a novel FLT3 agonist Fc fusion protein, in patients with advanced solid tumors

W1170 CXCL10 Expression and Biological Activities in Inflammatory Bowel Disease

Phase 1b dose escalation study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GS-3583, a FLT3 agonist Fc fusion protein, in patients with advanced solid tumors

GS-3583, a novel FLT3 agonist Fc fusion protein, to expand conventional dendritic cells in healthy volunteers

Assembly and regulation of the CD40 receptor complex in human B cells

Uncoupling of Nonreceptor Tyrosine Kinases from PLC-γ1 in an SLP-76- Deficient T Cell

BMS-936564 (Anti-CXCR4 Antibody) Induces Specific Leukemia Cell Mobilization and Objective Clinical Responses In CLL Patients Treated Under a Phase I Clinical Trial

A Novel Activating Mutation Of CXCR4 Plays a Crucial Role In Waldenstrom Macroglobulinemia Biology

CXCR4 Monoclonal Antibody, BMS-936564 (MDX-1338), Modulates Epithelial to Mesenchymal Transition (EMT) in Multiple Myeloma Cells

BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Anti Tumor Activity In Vivo

BMS-936564 (MDX1338): A Fully Human Anti-CXCR4 Antibody Induces Apoptosis in an in Vitro Model of Stromal – Leukemia Cell Interaction for Chronic Lymphocytic Leukemia

Characterization of MDX-1401, a Human Anti-CD30 Antibody with Enhanced Effector Function, for Therapy of Malignant Lymphoma

Linker for Activation of T Cells, {zeta}-Associated Protein-70, and Src Homology 2 Domain-Containing Leukocyte Protein-76 are Required for TCR-Induced Microtubule-Organizing Center Polarization

The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp

Uncoupling of nonreceptor tyrosine kinases from (PLC-gamma1) in an SLP-76--deficient T cell

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma-1 tyrosine kinases from PLC-gamma-1 in an SLP-76-deficient T cell

The association of insulin-elicited phosphotyrosine proteins with src homology 2 domains

Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C

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