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Targeting Chemokine Receptors in HIV : A Status Report

Annual review of pharmacology and toxicology, 2008-01, Vol.48 (1), p.425-461

2008

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HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry

Virology (New York, N.Y.), 2007-04, Vol.361 (1), p.212-228

2007

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Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D)

Virology (New York, N.Y.), 2005-07, Vol.338 (1), p.182-199

2005

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Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Journal of Virology, 2004-03, Vol.78 (6), p.2790-2807

2004

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HIV-1 Escape from a Small Molecule, CCR5-Specific Entry Inhibitor Does Not Involve CXCR4 Use

Proceedings of the National Academy of Sciences - PNAS, 2002-01, Vol.99 (1), p.395-400

2002

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Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss

PLoS pathogens, 2007-06, Vol.3 (6), p.e79-e79

2007

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Interaction of small molecule inhibitors of HIV-1 entry with CCR5

Virology (New York, N.Y.), 2006-05, Vol.349 (1), p.41-54

2006

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Analysis of the Mechanism by Which the Small-Molecule CCR5 Antagonists SCH-351125 and SCH-350581 Inhibit Human Immunodeficiency Virus Type 1 Entry

Journal of Virology, 2003-05, Vol.77 (9), p.5201-5208

2003

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Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1

Journal of Virology, 1998-04, Vol.72 (4), p.2855-2864

1998

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Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection

The Journal of experimental medicine, 2003-11, Vol.198 (10), p.1551-1562

2003

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Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

Virology (New York, N.Y.), 2007-08, Vol.364 (2), p.281-290

2007

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HIV-1 Escape From Small Molecule CCR5 Inhibitors In Vitro

Retrovirology, 2005-12, Vol.2 (S1), p.S5-S5, Article S5

Kuhmann, Shawn

2005

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The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4

Virology (New York, N.Y.), 2004-03, Vol.321 (1), p.8-22

2004

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Cooperation of Multiple CCR5 Coreceptors Is Required for Infections by Human Immunodeficiency Virus Type 1

Journal of Virology, 2000-08, Vol.74 (15), p.7005-7015

2000

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Enhancing the Proteolytic Maturation of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins

Journal of Virology, 2002-03, Vol.76 (6), p.2606-2616

2002

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The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry Is Explained by a Single Amino Acid Difference and Suggests a Mechanism of Action for These Inhibitors

Journal of Virology, 2004-04, Vol.78 (8), p.4134-4144

2004

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HIV-1 entry inhibitor entrances

Trends in pharmacological sciences (Regular ed.), 2004-03, Vol.25 (3), p.117-120

2004

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Adaptive Mutations in the V3 Loop of gp120 Enhance Fusogenicity of Human Immunodeficiency Virus Type 1 and Enable Use of a CCR5 Coreceptor That Lacks the Amino-Terminal Sulfated Region

Journal of Virology, 2001-12, Vol.75 (24), p.12266-12278

2001

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A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1

The Journal of biological chemistry, 1999-01, Vol.274 (4), p.1905-1913

1999

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Frequent Substitution Polymorphisms in African Green Monkey CCR5 Cluster at Critical Sites for Infections by Simian Immunodeficiency Virus SIVagm, Implying Ancient Virus-Host Coevolution

Journal of Virology, 2001-09, Vol.75 (18), p.8449-8460

2001

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The Fitness Cost to Human Immunodeficiency Virus Type 1 of Escaping From a Small Molecule CCR5 Inhibitor

Retrovirology, 2005-12, Vol.2 (S1), p.S9-S9, Article S9

2005

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Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1

The Journal of biological chemistry, 1999-08, Vol.274 (33), p.23499-23507

1999

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Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses

Journal of Virology, 1997-11, Vol.71 (11), p.8642-8656

1997

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Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter

Journal of Virology, 1996-10, Vol.70 (10), p.6884-6891

1996

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Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Journal of virology, 2004-06, Vol.78 (12), p.6706-6706

2004

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Targeting Chemokine Receptors in HIV : A Status Report

HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry

Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D)

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

HIV-1 Escape from a Small Molecule, CCR5-Specific Entry Inhibitor Does Not Involve CXCR4 Use

Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss

Interaction of small molecule inhibitors of HIV-1 entry with CCR5

Analysis of the Mechanism by Which the Small-Molecule CCR5 Antagonists SCH-351125 and SCH-350581 Inhibit Human Immunodeficiency Virus Type 1 Entry

Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1

Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection

Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

HIV-1 Escape From Small Molecule CCR5 Inhibitors In Vitro

The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4

Cooperation of Multiple CCR5 Coreceptors Is Required for Infections by Human Immunodeficiency Virus Type 1

Enhancing the Proteolytic Maturation of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins

The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry Is Explained by a Single Amino Acid Difference and Suggests a Mechanism of Action for These Inhibitors

HIV-1 entry inhibitor entrances

Adaptive Mutations in the V3 Loop of gp120 Enhance Fusogenicity of Human Immunodeficiency Virus Type 1 and Enable Use of a CCR5 Coreceptor That Lacks the Amino-Terminal Sulfated Region

A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1

Frequent Substitution Polymorphisms in African Green Monkey CCR5 Cluster at Critical Sites for Infections by Simian Immunodeficiency Virus SIVagm, Implying Ancient Virus-Host Coevolution

The Fitness Cost to Human Immunodeficiency Virus Type 1 of Escaping From a Small Molecule CCR5 Inhibitor

Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1

Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses

Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

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