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Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy

Nanoscale, 2018-11, Vol.10 (44), p.20851-20862

2018

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Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization

Cell reports (Cambridge), 2019-08, Vol.28 (7), p.1729-1743.e5

2019

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TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy

Molecular pharmaceutics, 2020-06, Vol.17 (6), p.2109-2124

2020

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Physiological microbial exposure transiently inhibits mouse lung ILC2 responses to allergens

Nature immunology, 2022-12, Vol.23 (12), p.1703

2022

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Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity

Frontiers in immunology, 2020-08, Vol.11, p.1786-1786

2020

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CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis

Cell reports (Cambridge), 2023-11, Vol.42 (11), p.113345, Article 113345

2023

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Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8

ACS medicinal chemistry letters, 2017-11, Vol.8 (11), p.1148-1152

2017

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Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses

Frontiers in immunology, 2018-10, Vol.9, p.2532-2532

2018

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Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy

PloS one, 2012-02, Vol.7 (2), p.e31085-e31085

2012

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Minimal changes in the systemic immune response after nephrectomy of localized renal masses

Urologic oncology, 2014-07, Vol.32 (5), p.589-600

2014

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TRAIL-expressing CD8+ T cells mediate tolerance following soluble peptide-induced peripheral T cell deletion

Journal of leukocyte biology, 2010-12, Vol.88 (6), p.1217-1225

2010

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Combination of Sunitinib and PD-L1 Blockade Enhances Anticancer Efficacy of TLR7/8 Agonist-Based Nanovaccine

Molecular pharmaceutics, 2019-03, Vol.16 (3), p.1200-1210

2019

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Natural Microbial Exposure from the Earliest Natural Time Point Enhances Immune Development by Expanding Immune Cell Progenitors and Mature Immune Cells

The Journal of immunology (1950), 2023-06, Vol.210 (11), p.1740-1751

2023

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Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy

The Journal of immunology (1950), 2018-10, Vol.201 (7), p.1837-1841

2018

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CD8 T Cells Utilize TRAIL to Control Influenza Virus Infection

The Journal of immunology (1950), 2008-10, Vol.181 (7), p.4918-4925

2008

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Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs

Bioorganic & medicinal chemistry letters, 2022-03, Vol.59, p.128548-128548, Article 128548

2022

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Reduced T Cell Priming in Microbially Experienced "Dirty" Mice Results from Limited IL-27 Production by XCR1+ Dendritic Cells

The Journal of immunology (1950), 2022-12, Vol.209 (11), p.2149-2159

2022

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Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo

The Journal of immunology (1950), 2016-12, Vol.197 (11), p.4301-4311

2016

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Gut Microbial Membership Modulates CD4 T Cell Reconstitution and Function after Sepsis

The Journal of immunology (1950), 2016-09, Vol.197 (5), p.1692-1698

2016

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Development and optimization of a diluted whole blood ELISpot assay to test immune function

Journal of immunological methods, 2024-10, Vol.533, p.113743, Article 113743

2024

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Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge

The Journal of immunology (1950), 2015-02, Vol.194 (4), p.1609-1620

2015

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CpG-mediated modulation of MDSC contributes to the efficacy of Ad5-TRAIL therapy against renal cell carcinoma

Cancer Immunology, Immunotherapy, 2014-11, Vol.63 (11), p.1213-1227

2014

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Effective TRAIL-based immunotherapy requires both plasmacytoid and CD8α dendritic cells

Cancer Immunology, Immunotherapy, 2014-07, Vol.63 (7), p.685-697

2014

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Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinoma

The FEBS journal, 2015-12, Vol.282 (24), p.4747-4765

2015

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Activation-Induced CD154 Expression Abrogates Tolerance Induced by Apoptotic Cells

The Journal of immunology (1950), 2009-11, Vol.183 (10), p.6114-6123

2009

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Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy

Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization

TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy

Physiological microbial exposure transiently inhibits mouse lung ILC2 responses to allergens

Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity

CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis

Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8

Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses

Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy

Minimal changes in the systemic immune response after nephrectomy of localized renal masses

TRAIL-expressing CD8+ T cells mediate tolerance following soluble peptide-induced peripheral T cell deletion

Combination of Sunitinib and PD-L1 Blockade Enhances Anticancer Efficacy of TLR7/8 Agonist-Based Nanovaccine

Natural Microbial Exposure from the Earliest Natural Time Point Enhances Immune Development by Expanding Immune Cell Progenitors and Mature Immune Cells

Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy

CD8 T Cells Utilize TRAIL to Control Influenza Virus Infection

Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs

Reduced T Cell Priming in Microbially Experienced "Dirty" Mice Results from Limited IL-27 Production by XCR1+ Dendritic Cells

Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo

Gut Microbial Membership Modulates CD4 T Cell Reconstitution and Function after Sepsis

Development and optimization of a diluted whole blood ELISpot assay to test immune function

Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge

CpG-mediated modulation of MDSC contributes to the efficacy of Ad5-TRAIL therapy against renal cell carcinoma

Effective TRAIL-based immunotherapy requires both plasmacytoid and CD8α dendritic cells

Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinoma

Activation-Induced CD154 Expression Abrogates Tolerance Induced by Apoptotic Cells

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