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Polymeric nanoparticles encapsulating novel TLR7/8 agonists as immunostimulatory adjuvants for enhanced cancer immunotherapy

Biomaterials, 2018-05, Vol.164, p.38-53

2018

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Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy

Nanoscale, 2018-11, Vol.10 (44), p.20851-20862

2018

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Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization

Cell reports (Cambridge), 2019-08, Vol.28 (7), p.1729-1743.e5

2019

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TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy

Molecular pharmaceutics, 2020-06, Vol.17 (6), p.2109-2124

2020

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Physiological microbial exposure transiently inhibits mouse lung ILC2 responses to allergens

Nature immunology, 2022-12, Vol.23 (12), p.1703

2022

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Combination of Sunitinib and PD-L1 Blockade Enhances Anticancer Efficacy of TLR7/8 Agonist-Based Nanovaccine

Molecular pharmaceutics, 2019-03, Vol.16 (3), p.1200-1210

2019

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Natural Microbial Exposure from the Earliest Natural Time Point Enhances Immune Development by Expanding Immune Cell Progenitors and Mature Immune Cells

The Journal of immunology (1950), 2023-06, Vol.210 (11), p.1740

2023

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Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy

The Journal of immunology (1950), 2018-10, Vol.201 (7), p.1837-1841

2018

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Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity

Frontiers in immunology, 2020-08, Vol.11, p.1786-1786

2020

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Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8

ACS medicinal chemistry letters, 2017-11, Vol.8 (11), p.1148-1152

2017

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CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis

Cell reports (Cambridge), 2023-11, Vol.42 (11), p.113345, Article 113345

2023

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CD8 T Cells Utilize TRAIL to Control Influenza Virus Infection

The Journal of immunology (1950), 2008-10, Vol.181 (7), p.4918-4925

2008

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Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs

Bioorganic & medicinal chemistry letters, 2022-03, Vol.59, p.128548-128548, Article 128548

2022

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Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses

Frontiers in immunology, 2018-10, Vol.9, p.2532-2532

2018

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Reduced T Cell Priming in Microbially Experienced "Dirty" Mice Results from Limited IL-27 Production by XCR1+ Dendritic Cells

The Journal of immunology (1950), 2022-12, Vol.209 (11), p.2149-2159

2022

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Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo

The Journal of immunology (1950), 2016-12, Vol.197 (11), p.4301-4311

2016

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Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy

PloS one, 2012-02, Vol.7 (2), p.e31085-e31085

2012

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Gut Microbial Membership Modulates CD4 T Cell Reconstitution and Function after Sepsis

The Journal of immunology (1950), 2016-09, Vol.197 (5), p.1692-1698

2016

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Diet-induced obesity alters dendritic cell function in the presence and absence of tumor growth

The Journal of immunology (1950), 2012-08, Vol.189 (3), p.1311-1321

2012

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Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge

The Journal of immunology (1950), 2015-02, Vol.194 (4), p.1609-1620

2015

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TRAIL gene therapy: from preclinical development to clinical application

Current gene therapy, 2009-02, Vol.9 (1), p.9

2009

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CpG-mediated modulation of MDSC contributes to the efficacy of Ad5-TRAIL therapy against renal cell carcinoma

Cancer Immunology, Immunotherapy, 2014-11, Vol.63 (11), p.1213-1227

2014

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Effective TRAIL-based immunotherapy requires both plasmacytoid and CD8α dendritic cells

Cancer Immunology, Immunotherapy, 2014-07, Vol.63 (7), p.685-697

2014

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Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinoma

The FEBS journal, 2015-12, Vol.282 (24), p.4747-4765

2015

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Minimal changes in the systemic immune response after nephrectomy of localized renal masses

Urologic oncology, 2014-07, Vol.32 (5), p.589-600

2014

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Polymeric nanoparticles encapsulating novel TLR7/8 agonists as immunostimulatory adjuvants for enhanced cancer immunotherapy

Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy

Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization

TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy

Physiological microbial exposure transiently inhibits mouse lung ILC2 responses to allergens

Combination of Sunitinib and PD-L1 Blockade Enhances Anticancer Efficacy of TLR7/8 Agonist-Based Nanovaccine

Natural Microbial Exposure from the Earliest Natural Time Point Enhances Immune Development by Expanding Immune Cell Progenitors and Mature Immune Cells

Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy

Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity

Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8

CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis

CD8 T Cells Utilize TRAIL to Control Influenza Virus Infection

Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs

Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses

Reduced T Cell Priming in Microbially Experienced "Dirty" Mice Results from Limited IL-27 Production by XCR1+ Dendritic Cells

Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo

Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy

Gut Microbial Membership Modulates CD4 T Cell Reconstitution and Function after Sepsis

Diet-induced obesity alters dendritic cell function in the presence and absence of tumor growth

Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge

TRAIL gene therapy: from preclinical development to clinical application

CpG-mediated modulation of MDSC contributes to the efficacy of Ad5-TRAIL therapy against renal cell carcinoma

Effective TRAIL-based immunotherapy requires both plasmacytoid and CD8α dendritic cells

Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinoma

Minimal changes in the systemic immune response after nephrectomy of localized renal masses

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