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New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine

Physiological research, 2018-01, Vol.67 (Suppl 1), p.S37-S54

2018

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Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system

British journal of pharmacology, 2007-08, Vol.151 (8), p.1143-1153

2007

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Orphan‐receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin‐1

British journal of pharmacology, 2000-10, Vol.131 (3), p.441-446

2000

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Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1

Canadian journal of physiology and pharmacology, 2010-06, Vol.88 (6), p.644

2010

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Characterization of the snake venom ligand [125I]‐DNP binding to natriuretic peptide receptor‐A in human artery and potent DNP mediated vasodilatation

British journal of pharmacology, 2006-12, Vol.149 (7), p.838-844

2006

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Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system

Canadian journal of physiology and pharmacology, 2002-05, Vol.80 (5), p.369-374

2002

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Characterization and Localization of Endothelin Receptor Subtypes in the Human Atrioventricular Conducting System and Myocardium

Circulation research, 1993-03, Vol.72 (3), p.526-538

1993

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Vasoconstrictor activity of novel endothelin peptide, ET‐1(1 – 31), in human mammary and coronary arteries in vitro

British journal of pharmacology, 2001-11, Vol.134 (6), p.1360-1366

2001

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17 Chemokine receptors as therapeutic targets in atherosclerosis: pharmacological characterisation of the human CCR5 knock-in mouse

Heart (British Cardiac Society), 2011-10, Vol.97 (20), p.e7-e7

2011

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Maternal Dexamethasone Increases Endothelin-1 Sensitivity and Endothelin A Receptor Expression in Ovine Foetal Placental Arteries

Placenta (Eastbourne), 2003-04, Vol.24 (4), p.392-402

2003

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Expression of endothelin peptides and mRNA in the human heart

Clinical science (1979), 1996-01, Vol.90 (1), p.37-46

1996

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Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin‐1, to distinguish between these agonists in binding experiments

British journal of pharmacology, 1996-05, Vol.118 (2), p.335-342

1996

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Characterization of two new ETB selective radioligands, [125I]‐BQ3020 and [125I]‐[Ala1,3,11,15]ET‐1 in human heart

British journal of pharmacology, 1992-11, Vol.107 (3), p.637-639

1992

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Endothelin ETA and ETB mRNA and receptors expressed by smooth muscle in the human vasculature: majority of the ETA sub‐type

British journal of pharmacology, 1995-03, Vol.114 (6), p.1110-1116

1995

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Vasoconstrictor endothelin receptors characterized in human renal artery and vein in vitro

British journal of pharmacology, 1994-09, Vol.113 (1), p.49-54

1994

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Identification and cellular localisation of NPW1 (GPR7) receptors for the novel neuropeptide W-23 by [125I]-NPW radioligand binding and immunocytochemistry

Brain research, 2004-08, Vol.1017 (1-2), p.222-226

2004

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The CCR5 chemokine receptor mediates vasoconstriction and stimulates intimal hyperplasia in human vessels in vitro

Cardiovascular research, 2014-03, Vol.101 (3), p.513-521

2014

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Characterization of [125I]‐PD164333, an ETA selective non‐peptide radiolabelled antagonist, in normal and diseased human tissues

British journal of pharmacology, 1998-01, Vol.123 (2), p.223-230

1998

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Novel ligands BQ123 and BQ3020 characterize endothelin receptor subtypes ETA and ETB in human kidney

Kidney international, 1993-07, Vol.44 (1), p.36-42

1993

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Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1

American journal of physiology. Regulatory, integrative and comparative physiology, 2001-07, Vol.281 (1), p.261-R268

2001

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Characterization of Endothelin Isoforms in Human Heart: Endothelin-2 Demonstrated

Journal of cardiovascular pharmacology, 1993, Vol.22 Suppl 8 (Supplement 8), p.S26-S28

1993

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Expression and Characterization of the Human Endothelin-A-Receptor in Pichia pastoris: Influence of N-Terminal Epitope Tags

Journal of cardiovascular pharmacology, 2000, Vol.36 Suppl 1 (5 Suppl 1), p.S55-S57

2000

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Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system

Cardiovascular research, 2009-02, Vol.81 (2), p.353-361

2009

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Expression of endothelin(A) receptors in human gliomas and meningiomas, with high affinity for the selective antagonist PD156707

Neurosurgery, 1998-10, Vol.43 (4), p.890-8; discussion 898-9

1998

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Endothelin-A-Receptors in Human Aorta and Pulmonary Arteries are Downregulated in Patients With Cardiovascular Disease: An Adaptive Response to Increased Levels of Endothelin-1?

Journal of cardiovascular pharmacology, 2000, Vol.36 Suppl 1 (5 Suppl 1), p.S377-S379

2000

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New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine

Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system

Orphan‐receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin‐1

Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1

Characterization of the snake venom ligand [125I]‐DNP binding to natriuretic peptide receptor‐A in human artery and potent DNP mediated vasodilatation

Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system

Characterization and Localization of Endothelin Receptor Subtypes in the Human Atrioventricular Conducting System and Myocardium

Vasoconstrictor activity of novel endothelin peptide, ET‐1(1 – 31), in human mammary and coronary arteries in vitro

17 Chemokine receptors as therapeutic targets in atherosclerosis: pharmacological characterisation of the human CCR5 knock-in mouse

Maternal Dexamethasone Increases Endothelin-1 Sensitivity and Endothelin A Receptor Expression in Ovine Foetal Placental Arteries

Expression of endothelin peptides and mRNA in the human heart

Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin‐1, to distinguish between these agonists in binding experiments

Characterization of two new ETB selective radioligands, [125I]‐BQ3020 and [125I]‐[Ala1,3,11,15]ET‐1 in human heart

Endothelin ETA and ETB mRNA and receptors expressed by smooth muscle in the human vasculature: majority of the ETA sub‐type

Vasoconstrictor endothelin receptors characterized in human renal artery and vein in vitro

Identification and cellular localisation of NPW1 (GPR7) receptors for the novel neuropeptide W-23 by [125I]-NPW radioligand binding and immunocytochemistry

The CCR5 chemokine receptor mediates vasoconstriction and stimulates intimal hyperplasia in human vessels in vitro

Characterization of [125I]‐PD164333, an ETA selective non‐peptide radiolabelled antagonist, in normal and diseased human tissues

Novel ligands BQ123 and BQ3020 characterize endothelin receptor subtypes ETA and ETB in human kidney

Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1

Characterization of Endothelin Isoforms in Human Heart: Endothelin-2 Demonstrated

Expression and Characterization of the Human Endothelin-A-Receptor in Pichia pastoris: Influence of N-Terminal Epitope Tags

Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system

Expression of endothelin(A) receptors in human gliomas and meningiomas, with high affinity for the selective antagonist PD156707

Endothelin-A-Receptors in Human Aorta and Pulmonary Arteries are Downregulated in Patients With Cardiovascular Disease: An Adaptive Response to Increased Levels of Endothelin-1?

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