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Cytotoxic effects of the anthraquinone derivatives 1′-deoxyrhodoptilometrin and (S)-(−)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp

Archives of toxicology, 2017-03, Vol.91 (3), p.1485-1495

2017

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Workflow Comparison for Label-Free, Quantitative Secretome Proteomics for Cancer Biomarker Discovery: Method Evaluation, Differential Analysis, and Verification in Serum

Journal of proteome research, 2010-04, Vol.9 (4), p.1913-1922

2010

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Phenolic compounds and their anti-oxidative properties and protein kinase inhibition from the Chinese mangrove plant Laguncularia racemosa

Phytochemistry (Oxford), 2010-03, Vol.71 (4), p.435-442

2010

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Meriolins, a new class of cell death -Inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (17), p.8325-8334

2007

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Arthrinins A–D: Novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp

Bioorganic & medicinal chemistry, 2011-08, Vol.19 (15), p.4644-4651

2011

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7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-ones Designed by a "Cut and Glue" Strategy Are Dual Aurora A/VEGF-R Kinase Inhibitors

Molecules (Basel, Switzerland), 2021-03, Vol.26 (6), p.1611

2021

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Cytotoxic Metabolites from the Fungal Endophyte Alternaria sp. and Their Subsequent Detection in Its Host Plant Polygonum senegalense

Journal of natural products (Washington, D.C.), 2008-06, Vol.71 (6), p.972-980

2008

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Regulation of p53 stability by Mdm2

Nature (London), 1997-05, Vol.387 (6630), p.299-303

1997

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Tri- and Tetrasubstituted Pyrazole Derivates: Regioisomerism Switches Activity from p38MAP Kinase to Important Cancer Kinases

Journal of medicinal chemistry, 2012-01, Vol.55 (2), p.961-965

2012

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Identification of a cryptic nucleolar-localization signal in MDM2

Nature cell biology, 2000-03, Vol.2 (3), p.179-181

2000

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Substituted 2-arylbenzothiazoles as kinase inhibitors: Hit-to-lead optimization

Bioorganic & medicinal chemistry, 2009-09, Vol.17 (18), p.6728-6737

2009

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Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model

Scientific reports, 2019-03, Vol.9 (1), p.4976-4976, Article 4976

2019

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Bioactive Metabolites from the Endophytic Fungus Stemphylium globuliferum Isolated from Mentha pulegium

Journal of natural products (Washington, D.C.), 2009-04, Vol.72 (4), p.626-631

2009

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2-Anilino-4-(benzimidazol-2-yl)pyrimidines – A multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines

European journal of medicinal chemistry, 2012-07, Vol.53, p.254-263

2012

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Assessing the Target Differentiation Potential of Imidazole-Based Protein Kinase Inhibitors

Journal of medicinal chemistry, 2012-12, Vol.55 (24), p.11067-11071

2012

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Identification of 2-Anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as Dual PLK1/VEGF-R2 Kinase Inhibitor Chemotypes by Structure-Based Lead Generation

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2433-2442

2010

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Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors

European journal of medicinal chemistry, 2014-01, Vol.71, p.1-14

2014

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Dual IGF-1R/SRC inhibitors based on a N′-aroyl-2-(1 H-indol-3-yl)-2-oxoacetohydrazide structure

European journal of medicinal chemistry, 2011-07, Vol.46 (7), p.2759-2769

2011

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Search for Inhibitors of Bacterial and Human Protein Kinases among Derivatives of Diazepines[1,4] Annelated with Maleimide and Indole Cycles

Journal of medicinal chemistry, 2008-12, Vol.51 (24), p.7731-7736

2008

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A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

BMC genomics, 2008-09, Vol.9 (1), p.441-441, Article 441

2008

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Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors

European journal of pharmaceutics and biopharmaceutics, 2018-05, Vol.126, p.89-94

2018

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Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells

Journal of pharmacy and pharmacology, 2013-09, Vol.65 (9), p.1393-1408

2013

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Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation

Molecular nutrition & food research, 2009-04, Vol.53 (4), p.431-440

2009

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Regulation of p53 Function and Stability by Phosphorylation

Molecular and Cellular Biology, 1999-03, Vol.19 (3), p.1751-1758

1999

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A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis

Frontiers in oncology, 2011, Vol.1, p.50-50

2011

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Cytotoxic effects of the anthraquinone derivatives 1′-deoxyrhodoptilometrin and (S)-(−)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp

Workflow Comparison for Label-Free, Quantitative Secretome Proteomics for Cancer Biomarker Discovery: Method Evaluation, Differential Analysis, and Verification in Serum

Phenolic compounds and their anti-oxidative properties and protein kinase inhibition from the Chinese mangrove plant Laguncularia racemosa

Meriolins, a new class of cell death -Inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases

Arthrinins A–D: Novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp

7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-ones Designed by a "Cut and Glue" Strategy Are Dual Aurora A/VEGF-R Kinase Inhibitors

Cytotoxic Metabolites from the Fungal Endophyte Alternaria sp. and Their Subsequent Detection in Its Host Plant Polygonum senegalense

Regulation of p53 stability by Mdm2

Tri- and Tetrasubstituted Pyrazole Derivates: Regioisomerism Switches Activity from p38MAP Kinase to Important Cancer Kinases

Identification of a cryptic nucleolar-localization signal in MDM2

Substituted 2-arylbenzothiazoles as kinase inhibitors: Hit-to-lead optimization

Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model

Bioactive Metabolites from the Endophytic Fungus Stemphylium globuliferum Isolated from Mentha pulegium

2-Anilino-4-(benzimidazol-2-yl)pyrimidines – A multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines

Assessing the Target Differentiation Potential of Imidazole-Based Protein Kinase Inhibitors

Identification of 2-Anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as Dual PLK1/VEGF-R2 Kinase Inhibitor Chemotypes by Structure-Based Lead Generation

Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors

Dual IGF-1R/SRC inhibitors based on a N′-aroyl-2-(1 H-indol-3-yl)-2-oxoacetohydrazide structure

Search for Inhibitors of Bacterial and Human Protein Kinases among Derivatives of Diazepines[1,4] Annelated with Maleimide and Indole Cycles

A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors

Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells

Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation

Regulation of p53 Function and Stability by Phosphorylation

A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis

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