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The MRP family of drug efflux pumps

Oncogene, 2003-10, Vol.22 (47), p.7537-7552

2003

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organic solute transporter α-β, Ostα-Ostβ, is essential for intestinal bile acid transport and homeostasis

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (10), p.3891-3896

2008

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Predicting drug sensitivity and resistance: Profiling ABC transporter genes in cancer cells

Cancer cell, 2004-08, Vol.6 (2), p.129-137

2004

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MRP8, ATP-binding Cassette C11 (ABCC11), Is a Cyclic Nucleotide Efflux Pump and a Resistance Factor for Fluoropyrimidines 2′,3′-Dideoxycytidine and 9′-(2′-Phosphonylmethoxyethyl)adenine

The Journal of biological chemistry, 2003-08, Vol.278 (32), p.29509-29514

2003

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Introduction to resistance to anticancer agents

Oncogene, 2003-10, Vol.22 (47), p.7262-7264

Kruh, Gary D

2003

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Human Multidrug Resistance Protein 7 (ABCC10) Is a Resistance Factor for Nucleoside Analogues and Epothilone B

Cancer research (Chicago, Ill.), 2009, Vol.69 (1), p.178-184

2009

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ABCC10, ABCC11, and ABCC12

Pflügers Archiv, 2007-02, Vol.453 (5), p.675-684

2007

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Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): Resistance to docetaxel

Cancer research (Chicago, Ill.), 2004-07, Vol.64 (14), p.4927-4930

2004

Volltextzugriff (PDF)

Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6)

Cancer research (Chicago, Ill.), 2002-11, Vol.62 (21), p.6172-6177

2002

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Analysis of the In Vivo Functions of Mrp3

Molecular pharmacology, 2005-07, Vol.68 (1), p.160-168

2005

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Influence of blood-brain barrier efflux pumps on the distribution of vincristine in brain and brain tumors

Neuro-oncology (Charlottesville, Va.), 2010-10, Vol.12 (10), p.1043-1049

2010

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The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Cancer research (Chicago, Ill.), 2008-11, Vol.68 (21), p.8881-8888

2008

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Transport of methotrexate, methotrexate polyglutamates, and 17β-estradiol 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport

Cancer research (Chicago, Ill.), 2003-07, Vol.63 (14), p.4048-4054

2003

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Characterization of the Transport Properties of Human Multidrug Resistance Protein 7 (MRP7, ABCC10)

Molecular pharmacology, 2003-02, Vol.63 (2), p.351-358

2003

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Predicting Human Tumor Drug Concentrations from a Preclinical Pharmacokinetic Model of Temozolomide Brain Disposition

Clinical cancer research, 2007-07, Vol.13 (14), p.4271-4279

2007

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Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system

Cancer research (Chicago, Ill.), 2002-06, Vol.62 (11), p.3144-3150

2002

Volltextzugriff (PDF)

Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice

Cancer and metastasis reviews, 2007-03, Vol.26 (1), p.5-14

2007

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Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11)

Molecular pharmacology, 2005-02, Vol.67 (2), p.545-557

2005

Volltextzugriff (PDF)

Contribution of Abcc10 (Mrp7) to In Vivo Paclitaxel Resistance as Assessed in Abcc10-/- Mice

Cancer research (Chicago, Ill.), 2011-05, Vol.71 (10), p.3649-3657

2011

Volltextzugriff (PDF)

Expression of ABCC-Type Nucleotide Exporters in Blasts of Adult Acute Myeloid Leukemia: Relation to Long-term Survival

Clinical cancer research, 2009-03, Vol.15 (5), p.1762-1769

2009

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ArgBP2γ interacts with Akt and p21-activated kinase-1 and promotes cell survival

The Journal of biological chemistry, 2016-10, Vol.291 (43), p.22845-22845

2016

Volltextzugriff (PDF)

Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport

Cancer research (Chicago, Ill.), 2001-10, Vol.61 (19), p.7225-7232

2001

Volltextzugriff (PDF)

Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance

Biochemical pharmacology, 2009-03, Vol.77 (6), p.993-1001

2009

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Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites

Journal of cell science, 2004-05, Vol.117 (Pt 12), p.2557-2568

2004

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Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models

Drug metabolism and disposition, 2011-11, Vol.39 (11), p.2155

2011

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The MRP family of drug efflux pumps

organic solute transporter α-β, Ostα-Ostβ, is essential for intestinal bile acid transport and homeostasis

Predicting drug sensitivity and resistance: Profiling ABC transporter genes in cancer cells

MRP8, ATP-binding Cassette C11 (ABCC11), Is a Cyclic Nucleotide Efflux Pump and a Resistance Factor for Fluoropyrimidines 2′,3′-Dideoxycytidine and 9′-(2′-Phosphonylmethoxyethyl)adenine

Introduction to resistance to anticancer agents

Human Multidrug Resistance Protein 7 (ABCC10) Is a Resistance Factor for Nucleoside Analogues and Epothilone B

ABCC10, ABCC11, and ABCC12

Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): Resistance to docetaxel

Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6)

Analysis of the In Vivo Functions of Mrp3

Influence of blood-brain barrier efflux pumps on the distribution of vincristine in brain and brain tumors

The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Transport of methotrexate, methotrexate polyglutamates, and 17β-estradiol 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport

Characterization of the Transport Properties of Human Multidrug Resistance Protein 7 (MRP7, ABCC10)

Predicting Human Tumor Drug Concentrations from a Preclinical Pharmacokinetic Model of Temozolomide Brain Disposition

Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system

Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice

Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11)

Contribution of Abcc10 (Mrp7) to In Vivo Paclitaxel Resistance as Assessed in Abcc10-/- Mice

Expression of ABCC-Type Nucleotide Exporters in Blasts of Adult Acute Myeloid Leukemia: Relation to Long-term Survival

ArgBP2γ interacts with Akt and p21-activated kinase-1 and promotes cell survival

Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport

Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance

Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models

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