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Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice

Hepatology (Baltimore, Md.), 2015-01, Vol.61 (1), p.238-248

2015

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Elevated systemic levels of the matrix metalloproteinase inhibitor TIMP-1 correlate with clinical markers of cachexia in patients with chronic pancreatitis and pancreatic cancer

BMC cancer, 2018-02, Vol.18 (1), p.128-128, Article 128

2018

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Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow

Molecular cancer research, 2016-11, Vol.14 (11), p.1147-1158

2016

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Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site

Angewandte Chemie (International ed.), 2014-10, Vol.53 (44), p.11969-11973

International ed. in English, 2014

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Recognizing the Molecular Multifunctionality and Interactome of TIMP-1

Trends in cell biology, 2019-01, Vol.29 (1), p.6-19

2019

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Metalloproteinase‐dependent and ‐independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs‐15

International journal of cancer, 2015-02, Vol.136 (4), p.E14-E26

2015

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Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill

Cancers, 2021-04, Vol.13 (7), p.1679

2021

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Premetastatic niche formation in the liver: emerging mechanisms and mouse models

Journal of Molecular Medicine, 2015-11, Vol.93 (11), p.1193-1201

Krüger, Achim

2015

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Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer

Cancer research (Chicago, Ill.), 2006-05, Vol.66 (10), p.5242-5250

2006

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Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the [alpha]-Ketoamide Electrophile as an Auspicious Reversible Lead Motif

Angewandte Chemie (International ed.), 2014-02, Vol.53 (6), p.1679-1683

International ed. in English, 2014

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Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation

ChemMedChem, 2015-12, Vol.10 (12), p.1969-1973

2015

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Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes

Biological chemistry, 2012-12, Vol.393 (12), p.1449-1455

2012

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Overexpression of the urokinase receptor mRNA splice variant uPAR-del4/5 affects tumor-associated processes of breast cancer cells in vitro and in vivo

Breast cancer research and treatment, 2011-06, Vol.127 (3), p.649-657

2011

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Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424)

Cancer research (Chicago, Ill.), 2002-08, Vol.62 (16), p.4617-4622

2002

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Use of Intestinal Ultrasound to Monitor Crohn’s Disease Activity

Clinical gastroenterology and hepatology, 2017-04, Vol.15 (4), p.535-542.e2

2017

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Inside Cover: Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation (ChemMedChem 12/2015)

ChemMedChem, 2015-12, Vol.10 (12), p.1942-1942

2015

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The influence of the stable expression of BMP2 in fibrin clots on the remodelling and repair of osteochondral defects

Biomaterials, 2009-04, Vol.30 (12), p.2385-2392

2009

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Selektive Inhibition des Immunoproteasoms durch ligandeninduzierte Vernetzung des katalytischen Zentrums

Angewandte Chemie, 2014-10, Vol.126 (44), p.12163-12167

2014

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Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver

Gastroenterology (New York, N.Y. 1943), 2016-11, Vol.151 (5), p.1011-1024.e7

2016

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Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (18), p.8615-8623

2007

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Urokinase-type plasminogen activator (uPA) and its receptor (uPAR): development of antagonists of uPA/uPAR interaction and their effects in vitro and in vivo

Current pharmaceutical design, 2003-01, Vol.9 (19), p.1529

2003

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Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment

Cancer research (Chicago, Ill.), 2006-01, Vol.66 (2), p.936-943

2006

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In vivo analysis of retroviral gene transfer to chondrocytes within collagen scaffolds for the treatment of osteochondral defects

Biomaterials, 2007-10, Vol.28 (30), p.4480-4487

2007

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Hydroxamate-type matrix metalloproteinase inhibitor batimastat promotes liver metastasis

Cancer research (Chicago, Ill.), 2001-02, Vol.61 (4), p.1272-1275

2001

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Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice

Elevated systemic levels of the matrix metalloproteinase inhibitor TIMP-1 correlate with clinical markers of cachexia in patients with chronic pancreatitis and pancreatic cancer

Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow

Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site

Recognizing the Molecular Multifunctionality and Interactome of TIMP-1

Metalloproteinase‐dependent and ‐independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs‐15

Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill

Premetastatic niche formation in the liver: emerging mechanisms and mouse models

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer

Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the [alpha]-Ketoamide Electrophile as an Auspicious Reversible Lead Motif

Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation

Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes

Overexpression of the urokinase receptor mRNA splice variant uPAR-del4/5 affects tumor-associated processes of breast cancer cells in vitro and in vivo

Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424)

Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice

Use of Intestinal Ultrasound to Monitor Crohn’s Disease Activity

Inside Cover: Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation (ChemMedChem 12/2015)

The influence of the stable expression of BMP2 in fibrin clots on the remodelling and repair of osteochondral defects

Selektive Inhibition des Immunoproteasoms durch ligandeninduzierte Vernetzung des katalytischen Zentrums

Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver

Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling

Urokinase-type plasminogen activator (uPA) and its receptor (uPAR): development of antagonists of uPA/uPAR interaction and their effects in vitro and in vivo

Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment

In vivo analysis of retroviral gene transfer to chondrocytes within collagen scaffolds for the treatment of osteochondral defects

Hydroxamate-type matrix metalloproteinase inhibitor batimastat promotes liver metastasis

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