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Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism

Pharmacology & therapeutics (Oxford), 2005-06, Vol.106 (3), p.357-387

2005

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Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

Toxicology and applied pharmacology, 2012-11, Vol.264 (3), p.377-386

2012

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Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse

Toxicology and applied pharmacology, 2015-09, Vol.287 (2), p.149-160

2015

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Flavin-containing monooxygenase-3: Induction by 3-methylcholanthrene and complex regulation by xenobiotic chemicals in hepatoma cells and mouse liver

Toxicology and applied pharmacology, 2010-08, Vol.247 (1), p.60-69

2010

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Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: II. Expression and role of flavin-containing monooxygenases and peroxidases

The Journal of pharmacology and experimental therapeutics, 2006-10, Vol.319 (1), p.497-505

2006

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Mammalian flavin-containing monooxygenase (FMO) as a source of hydrogen peroxide

Biochemical pharmacology, 2014-05, Vol.89 (1), p.141-147

2014

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Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants

The Journal of pharmacology and experimental therapeutics, 2007-01, Vol.320 (1), p.266-273

2007

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Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms

Biochemical pharmacology, 2008-01, Vol.75 (2), p.570-579

2008

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Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction

Food and chemical toxicology, 2018-05, Vol.115, p.136-147

2018

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Metabolism and pharmacokinetics of the anti-tuberculosis drug ethionamide in a flavin-containing monooxygenase null mouse

Pharmaceuticals (Basel, Switzerland), 2012-10, Vol.5 (11), p.1147-1159

2012

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Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K

Drug metabolism and disposition, 2009-08, Vol.37 (8), p.1785-1791

2009

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Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential

Toxicological sciences, 2015-07, Vol.146 (1), p.135-145

2015

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Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein

Drug metabolism and disposition, 2002-01, Vol.30 (1), p.34-41

2002

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Dibenzo[def,p]chrysene transplacental carcinogenesis in wild‐type, Cyp1b1 knockout, and CYP1B1 humanized mice

Molecular carcinogenesis, 2017-01, Vol.56 (1), p.163-171

2017

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Differences in FMO21 allelic frequency between Hispanics of Puerto Rican and Mexican descent

Drug metabolism and disposition, 2004-12, Vol.32 (12), p.1337

2004

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Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones

Toxicology and applied pharmacology, 2014-07, Vol.278 (2), p.91-99

2014

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Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes

Toxicology and applied pharmacology, 2008-12, Vol.233 (3), p.420-427

2008

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C-terminal truncation of rabbit flavin-containing monooxygenase isoform 2 enhances solubility

Archives of biochemistry and biophysics, 2006-06, Vol.450 (2), p.149-156

2006

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α-Tocopherol modulates Cyp3a expression, increases γ-CEHC production, and limits tissue γ-tocopherol accumulation in mice fed high γ-tocopherol diets

Free radical biology & medicine, 2005-03, Vol.38 (6), p.773-785

2005

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Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin

Toxicology and applied pharmacology, 2013-03, Vol.267 (2), p.192-199

2013

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Human Flavin-Containing Monooxygenase Form 2 S-Oxygenation: Sulfenic Acid Formation from Thioureas and Oxidation of Glutathione

Chemical research in toxicology, 2004-05, Vol.17 (5), p.633-640

2004

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S-Oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2

Biochemical pharmacology, 2004-09, Vol.68 (5), p.959-967

2004

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The Role of Flavin-Containing Monooxygenase (FMO) in the Metabolism of Tamoxifen and Other Tertiary Amines

Drug metabolism reviews, 2006, Vol.38 (1-2), p.139-147

2006

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In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring : Role of the aryl hydrocarbon receptor

Cancer research (Chicago, Ill.), 2006-01, Vol.66 (2), p.755-762

2006

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Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene

Carcinogenesis (New York), 2006-10, Vol.27 (10), p.2116-2123

2006

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Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism

Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse

Flavin-containing monooxygenase-3: Induction by 3-methylcholanthrene and complex regulation by xenobiotic chemicals in hepatoma cells and mouse liver

Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: II. Expression and role of flavin-containing monooxygenases and peroxidases

Mammalian flavin-containing monooxygenase (FMO) as a source of hydrogen peroxide

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants

Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms

Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction

Metabolism and pharmacokinetics of the anti-tuberculosis drug ethionamide in a flavin-containing monooxygenase null mouse

Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K

Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential

Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein

Dibenzo[def,p]chrysene transplacental carcinogenesis in wild‐type, Cyp1b1 knockout, and CYP1B1 humanized mice

Differences in FMO21 allelic frequency between Hispanics of Puerto Rican and Mexican descent

Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones

Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes

C-terminal truncation of rabbit flavin-containing monooxygenase isoform 2 enhances solubility

α-Tocopherol modulates Cyp3a expression, increases γ-CEHC production, and limits tissue γ-tocopherol accumulation in mice fed high γ-tocopherol diets

Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin

Human Flavin-Containing Monooxygenase Form 2 S-Oxygenation: Sulfenic Acid Formation from Thioureas and Oxidation of Glutathione

S-Oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2

The Role of Flavin-Containing Monooxygenase (FMO) in the Metabolism of Tamoxifen and Other Tertiary Amines

In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring : Role of the aryl hydrocarbon receptor

Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene

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