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Towards the prevention of potential aluminum toxic effects and an effective treatment for Alzheimer's disease

Journal of inorganic biochemistry, 2011-11, Vol.105 (11), p.1505-1512

2011

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Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture

Journal of inorganic biochemistry, 2005-09, Vol.99 (9), p.1895-1898

2005

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A novel trivalent cation chelator Feralex dissociates binding of aluminum and iron associated with hyperphosphorylated τ of Alzheimer’s disease

Brain research, 2003-01, Vol.961 (1), p.139-146

2003

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Synergistic effects of iron and aluminum on stress-related gene expression in primary human neural cells

Journal of Alzheimer's disease, 2005-11, Vol.8 (2), p.117-127

2005

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Synthesis of feralex a novel aluminum/iron chelating compound

Journal of inorganic biochemistry, 2002, Vol.88 (1), p.19-24

2002

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Molecular shuttle chelation: the use of ascorbate, desferrioxamine and Feralex-G in combination to remove nuclear bound aluminum

Cellular and molecular neurobiology, 2004-06, Vol.24 (3), p.443-459

2004

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Epidemic pathogenic selection: an explanation for hereditary hemochromatosis?

Medical hypotheses, 2002-09, Vol.59 (3), p.325-329

2002

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The cellular prion protein binds copper in vivo

Nature (London), 1997-12, Vol.390 (6661), p.684-687

1997

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A predictor for side effects in patients with Alzheimer's disease treated with deferoxamine mesylate

Clinical pharmacology and therapeutics, 1993-01, Vol.53 (1), p.30-37

1993

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Suppression of deferoxamine mesylate treatment - induced side effects by coadministration of isoniazid in a patient with Alzheimer's disease subject to aluminum removal by ionspecific chelation

Clinical pharmacology and therapeutics, 1990-10, Vol.48 (4), p.439-446

1990

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P1-382 Using chelators in binary and tertiary combination to remove neurotoxic metal: ascorbate, desferrioxamine, feralex-G and molecular shuttle chelation

Neurobiology of aging, 2004-07, Vol.25, p.S207-S207

2004

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Resolution of allelic and non-allelic variants of histone H1 by cation-exchange-hydrophilic-interaction chromatography

Journal of chromatography. B, Biomedical sciences and applications, 2000-07, Vol.744 (1), p.33-46

2000

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Neurotoxins from Bungarus fasciatus venom: a simple fractionation and separation of .alpha.- and .beta.-type neurotoxins and their partial characterization

Biochemistry (Easton), 1982-10, Vol.21 (21), p.5302-5309

1982

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P3-270: Metal ion-induced gene expression patterns in aging human brain cells in primary culture; implications for neurodegeneration and Alzheimer’s disease

Alzheimer's & dementia, 2006-07, Vol.2 (3), p.S454-S455

2006

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Structure of the Species in the Copper (II)-L-Histidine System

Canadian journal of chemistry, 1973-11, Vol.51 (21), p.3563-3571

1973

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Equilibria of the Simultaneously Existing Multiple Species in the Copper(II)-L-Histidine System

Canadian journal of chemistry, 1973-01, Vol.51 (21), p.3549-3554

1973

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Ternary Coordination Complexes Between Copper(II) and Amino Acids, and an Appraisal of the Enhancement of Ternary Complex Stability

Canadian journal of chemistry, 1973-11, Vol.51 (21), p.3555-3562

1973

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Are hereditary hemochromatosis mutations involved in Alzheimer disease?

American journal of medical genetics, 2000-07, Vol.93 (1), p.58-66

2000

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Theoretical Considerations and Equilibrium Conditions in Analytical Potentiometry. Computer Facilitated Mathematical Analysis of Equilibria in a Multicomponent System

Canadian journal of chemistry, 1973-11, Vol.51 (21), p.3541-3548

1973

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Equilibriums and structures of the species in the ternary system of L-histidine, copper(II) and diglycyl-L-histidine, a peptide mimicking the copper(II)-transport site of human serum albumin

Inorganic chemistry, 1975-10, Vol.14 (10), p.2383-2388

1975

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Molecular design to mimic the copper(II) transport site of human albumin: studies of equilibria between copper(II) and glycylglycyl-L-histidine-N-methyl amide and comparison with human albumin

Canadian journal of chemistry, 1976-04, Vol.54 (8), p.1300-1308

1976

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CAN THE CONTROVERSY OF THE ROLE OF ALUMINUM IN ALZHEIMER'S DISEASE BE RESOLVED? WHAT ARE THE SUGGESTED APPROACHES TO THIS CONTROVERSY AND METHODOLOGICAL ISSUES TO BE CONSIDERED?

Journal of Toxicology and Environmental Health, Part A, 1996-08, Vol.48 (6), p.615-636

1996

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A Peptide Molecule Mimicking the Copper(II) Transport Site of Human Serum Albumin

The Journal of biological chemistry, 1974-09, Vol.249 (18), p.5878-5884

1974

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A comparative study of Zn(II) and Co(II) binding to glycly- l-tyrosine, a pseudosubstrate for carboxypeptidase A

Journal of inorganic biochemistry, 1979, Vol.10 (1), p.1-8

1979

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Aluminum and Alzheimer's disease

Canadian Medical Association journal (CMAJ), 1994-08, Vol.151 (3), p.268

Munoz, D G

1994

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Towards the prevention of potential aluminum toxic effects and an effective treatment for Alzheimer's disease

Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture

A novel trivalent cation chelator Feralex dissociates binding of aluminum and iron associated with hyperphosphorylated τ of Alzheimer’s disease

Synergistic effects of iron and aluminum on stress-related gene expression in primary human neural cells

Synthesis of feralex a novel aluminum/iron chelating compound

Molecular shuttle chelation: the use of ascorbate, desferrioxamine and Feralex-G in combination to remove nuclear bound aluminum

Epidemic pathogenic selection: an explanation for hereditary hemochromatosis?

The cellular prion protein binds copper in vivo

A predictor for side effects in patients with Alzheimer's disease treated with deferoxamine mesylate

Suppression of deferoxamine mesylate treatment - induced side effects by coadministration of isoniazid in a patient with Alzheimer's disease subject to aluminum removal by ionspecific chelation

P1-382 Using chelators in binary and tertiary combination to remove neurotoxic metal: ascorbate, desferrioxamine, feralex-G and molecular shuttle chelation

Resolution of allelic and non-allelic variants of histone H1 by cation-exchange-hydrophilic-interaction chromatography

Neurotoxins from Bungarus fasciatus venom: a simple fractionation and separation of .alpha.- and .beta.-type neurotoxins and their partial characterization

P3-270: Metal ion-induced gene expression patterns in aging human brain cells in primary culture; implications for neurodegeneration and Alzheimer’s disease

Structure of the Species in the Copper (II)-L-Histidine System

Equilibria of the Simultaneously Existing Multiple Species in the Copper(II)-L-Histidine System

Ternary Coordination Complexes Between Copper(II) and Amino Acids, and an Appraisal of the Enhancement of Ternary Complex Stability

Are hereditary hemochromatosis mutations involved in Alzheimer disease?

Theoretical Considerations and Equilibrium Conditions in Analytical Potentiometry. Computer Facilitated Mathematical Analysis of Equilibria in a Multicomponent System

Equilibriums and structures of the species in the ternary system of L-histidine, copper(II) and diglycyl-L-histidine, a peptide mimicking the copper(II)-transport site of human serum albumin

Molecular design to mimic the copper(II) transport site of human albumin: studies of equilibria between copper(II) and glycylglycyl-L-histidine-N-methyl amide and comparison with human albumin

CAN THE CONTROVERSY OF THE ROLE OF ALUMINUM IN ALZHEIMER'S DISEASE BE RESOLVED? WHAT ARE THE SUGGESTED APPROACHES TO THIS CONTROVERSY AND METHODOLOGICAL ISSUES TO BE CONSIDERED?

A Peptide Molecule Mimicking the Copper(II) Transport Site of Human Serum Albumin

A comparative study of Zn(II) and Co(II) binding to glycly- l-tyrosine, a pseudosubstrate for carboxypeptidase A

Aluminum and Alzheimer's disease

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