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Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies

Cold Spring Harbor perspectives in medicine, 2019-11, Vol.9 (11), p.a033548

2019

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Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells

PloS one, 2011-04, Vol.6 (4), p.e19183-e19183

2011

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Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.14918-14923

2014

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The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano -electrical transducer channels

The Journal of physiology, 2005-09, Vol.567 (2), p.505-521

2005

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Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells

Nature neuroscience, 2011-06, Vol.14 (6), p.711-717

2011

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The impact of the Nitrates Directive on nitrogen emissions from agriculture in the EU-27 during 2000–2008

The Science of the total environment, 2014-01, Vol.468-469, p.1225-1233

2014

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Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea

The Journal of physiology, 2020-01, Vol.598 (1), p.151-170

2020

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Preferential Cochleotoxicity of Cisplatin

Frontiers in neuroscience, 2021-07, Vol.15, p.695268-695268

2021

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Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells

Cell death & disease, 2018-09, Vol.9 (9), p.922-13, Article 922

2018

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Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation

Nature communications, 2018-10, Vol.9 (1), p.4015-15, Article 4015

2018

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Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel

Journal of medicinal chemistry, 2019-06, Vol.62 (11), p.5312-5329

2019

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Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells

The Journal of neuroscience, 2016-01, Vol.36 (2), p.336-349

2016

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Maximizing agricultural reuse of recycled nutrients: A spatially explicit assessment of environmental consequences and costs

Journal of environmental management, 2023-04, Vol.332, p.117378-117378, Article 117378

2023

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The impact of nitrogen deposition on carbon sequestration by European forests and heathlands

Forest ecology and management, 2009-09, Vol.258 (8), p.1814-1823

2009

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Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells

The EMBO journal, 2019-05, Vol.38 (9), p.n/a

2019

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Sodium and calcium currents shape action potentials in immature mouse inner hair cells

The Journal of physiology, 2003-11, Vol.552 (3), p.743-761

2003

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Gentamicin Affects the Bioenergetics of Isolated Mitochondria and Collapses the Mitochondrial Membrane Potential in Cochlear Sensory Hair Cells

Frontiers in cellular neuroscience, 2019-09, Vol.13, p.416

2019

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Wake up your ears! ATP sculpts development along the auditory system

The Journal of physiology, 2017-02, Vol.595 (4), p.1019-1020

Kros, Corné J.

2017

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Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel

The Journal of neuroscience, 2014-04, Vol.34 (16), p.5505-5514

2014

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helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (49), p.19583-19588

2007

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Increase in efficiency and reduction in Ca2+ dependence of exocytosis during development of mouse inner hair cells

The Journal of physiology, 2005-02, Vol.563 (1), p.177-191

2005

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Tmc1 is necessary for normal functional maturation and survival of inner and outer hair cells in the mouse cochlea

The Journal of physiology, 2006-08, Vol.574 (3), p.677-698

2006

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The acquisition of mechano‐electrical transducer current adaptation in auditory hair cells requires myosin VI

The Journal of physiology, 2016-07, Vol.594 (13), p.3667-3681

2016

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Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial

European journal of cancer (1990), 2018-05, Vol.94, p.168-178

2018

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Development and properties of stereociliary link types in hair cells of the mouse cochlea

Journal of comparative neurology (1911), 2005-04, Vol.485 (1), p.75-85

2005

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Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies

Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells

Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells

The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano -electrical transducer channels

Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells

The impact of the Nitrates Directive on nitrogen emissions from agriculture in the EU-27 during 2000–2008

Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea

Preferential Cochleotoxicity of Cisplatin

Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells

Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation

Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel

Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells

Maximizing agricultural reuse of recycled nutrients: A spatially explicit assessment of environmental consequences and costs

The impact of nitrogen deposition on carbon sequestration by European forests and heathlands

Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells

Sodium and calcium currents shape action potentials in immature mouse inner hair cells

Gentamicin Affects the Bioenergetics of Isolated Mitochondria and Collapses the Mitochondrial Membrane Potential in Cochlear Sensory Hair Cells

Wake up your ears! ATP sculpts development along the auditory system

Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel

helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

Increase in efficiency and reduction in Ca2+ dependence of exocytosis during development of mouse inner hair cells

Tmc1 is necessary for normal functional maturation and survival of inner and outer hair cells in the mouse cochlea

The acquisition of mechano‐electrical transducer current adaptation in auditory hair cells requires myosin VI

Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial

Development and properties of stereociliary link types in hair cells of the mouse cochlea

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