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Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice

PloS one, 2018-01, Vol.13 (1), p.e0191225-e0191225

2018

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Evaluation of an Intravitreal Rho-Associated Kinase Inhibitor Depot Formulation in a Rat Model of Diabetic Retinopathy

Pharmaceutics, 2021-07, Vol.13 (8), p.1105

2021

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Quantification of Drugs in Distinctly Separated Ocular Substructures of Albino and Pigmented Rats

Pharmaceutics, 2020-12, Vol.12 (12), p.1174

2020

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PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition

Neurobiology of aging, 2014-09, Vol.35 (9), p.2072-2078

2014

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Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus

Synapse (New York, N.Y.), 2015-10, Vol.69 (10), p.484-496

2015

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Inhibition of acetylcholinesterase and phosphodiesterase-9A has differential effects on hippocampal early and late LTP

Neuropharmacology, 2012-04, Vol.62 (5-6), p.1964-1974

2012

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Differential effects of subtype-specific nicotinic acetylcholine receptor agonists on early and late hippocampal LTP

European journal of pharmacology, 2011-12, Vol.671 (1-3), p.26-32

2011

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Physical Properties and Effect in a Battery of Safety Pharmacology Models for Three Structurally Distinct Enteric Polymers Employed as Spray-Dried Dispersion Carriers

Frontiers in pharmacology, 2016-10, Vol.7, p.368-368

2016

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Restoring long-term potentiation impaired by amyloid-beta oligomers: Comparison of an acetylcholinesterase inhibitior and selective neuronal nicotinic receptor agonists

Brain research bulletin, 2013-07, Vol.96, p.28-38

2013

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A Small-Molecule-Responsive Riboswitch Enables Conditional Induction of Viral Vector-Mediated Gene Expression in Mice

ACS synthetic biology, 2020-06, Vol.9 (6), p.1292-1305

2020

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Differential effect of the mGlu5 receptor positive allosteric modulator ADX-47273 on early and late hippocampal LTP

Neuropharmacology, 2011-09, Vol.61 (4), p.707-714

2011

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sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca2+ homeostasis and CREB1-signaling

Experimental neurology, 2018-06, Vol.304, p.1-13

2018

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Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression

Alzheimer's research & therapy, 2017-03, Vol.9 (1), p.17-17, Article 17

2017

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Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation

Journal of neuroscience research, 2016-03, Vol.94 (3), p.266-281

2016

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Globular and Protofibrillar Aβ Aggregates Impair Neurotransmission by Different Mechanisms

Biochemistry (Easton), 2013-02, Vol.52 (8), p.1466-1476

2013

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Poster #M15 PRE-SYNAPTIC LOCALIZATION OF PDE2 ENZYME AND PHARMACOLOGICAL CHARACTERIZATION OF THE PDE2 INHIBITOR PF-999 IN MODELS RELATED TO COGNITIVE SYMPTOMS OF SCHIZOPHRENIA

Schizophrenia research, 2014-04, Vol.153, p.S194-S194

2014

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sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca 2+ homeostasis and CREB1-signaling

Experimental neurology, 2018-06, Vol.304, p.1

2018

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Translational Neuroscience: Toward New Therapies

1, 2015

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Pathophysiological Toolkit

Translational Neuroscience, 2015

2015

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Efficacy of cognitive behavioral internet-based therapy in parents after the loss of a child during pregnancy: pilot data from a randomized controlled trial

Archives of women's mental health, 2011-12, Vol.14 (6), p.465-477

2011

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Brief Internet-Based Intervention Reduces Posttraumatic Stress and Prolonged Grief in Parents after the Loss of a Child during Pregnancy: A Randomized Controlled Trial

Psychotherapy and psychosomatics, 2013-01, Vol.82 (6), p.372-381

2013

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S31. ENHANCEMENT OF SYNAPTIC PLASTICITY BY COMBINATION OF PDE2 AND PDE9 INHIBITION PRESUMABLY VIA PRE- AND POST-SYNAPTIC MECHANISMS

Schizophrenia bulletin, 2020-05, Vol.46 (Supplement_1), p.S43-S43

2020

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A multi-slice recording system for stable late phase hippocampal long-term potentiation experiments

Journal of neuroscience methods, 2011-01, Vol.194 (2), p.394-401

2011

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Neural Activation Underlying Acute Grief in Women After the Loss of an Unborn Child

The American journal of psychiatry, 2009-12, Vol.166 (12), p.1402-1410

2009

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P2‐399: RESTORING LONG‐TERM POTENTIATION IMPAIRED BY AMYLOID‐BETA OLIGOMERS: COMPARISON OF A BROADLY‐SPECIFIC ANTI AMYLOID‐BETA NANOBODY AND A MONOMER‐SPECIFIC ANTIBODY

Alzheimer's & dementia, 2014-07, Vol.10, p.P625-P625

2014

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Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice

Evaluation of an Intravitreal Rho-Associated Kinase Inhibitor Depot Formulation in a Rat Model of Diabetic Retinopathy

Quantification of Drugs in Distinctly Separated Ocular Substructures of Albino and Pigmented Rats

PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition

Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus

Inhibition of acetylcholinesterase and phosphodiesterase-9A has differential effects on hippocampal early and late LTP

Differential effects of subtype-specific nicotinic acetylcholine receptor agonists on early and late hippocampal LTP

Physical Properties and Effect in a Battery of Safety Pharmacology Models for Three Structurally Distinct Enteric Polymers Employed as Spray-Dried Dispersion Carriers

Restoring long-term potentiation impaired by amyloid-beta oligomers: Comparison of an acetylcholinesterase inhibitior and selective neuronal nicotinic receptor agonists

A Small-Molecule-Responsive Riboswitch Enables Conditional Induction of Viral Vector-Mediated Gene Expression in Mice

Differential effect of the mGlu5 receptor positive allosteric modulator ADX-47273 on early and late hippocampal LTP

sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca2+ homeostasis and CREB1-signaling

Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression

Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation

Globular and Protofibrillar Aβ Aggregates Impair Neurotransmission by Different Mechanisms

Poster #M15 PRE-SYNAPTIC LOCALIZATION OF PDE2 ENZYME AND PHARMACOLOGICAL CHARACTERIZATION OF THE PDE2 INHIBITOR PF-999 IN MODELS RELATED TO COGNITIVE SYMPTOMS OF SCHIZOPHRENIA

sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca 2+ homeostasis and CREB1-signaling

Translational Neuroscience: Toward New Therapies

Pathophysiological Toolkit

Efficacy of cognitive behavioral internet-based therapy in parents after the loss of a child during pregnancy: pilot data from a randomized controlled trial

Brief Internet-Based Intervention Reduces Posttraumatic Stress and Prolonged Grief in Parents after the Loss of a Child during Pregnancy: A Randomized Controlled Trial

S31. ENHANCEMENT OF SYNAPTIC PLASTICITY BY COMBINATION OF PDE2 AND PDE9 INHIBITION PRESUMABLY VIA PRE- AND POST-SYNAPTIC MECHANISMS

A multi-slice recording system for stable late phase hippocampal long-term potentiation experiments

Neural Activation Underlying Acute Grief in Women After the Loss of an Unborn Child

P2‐399: RESTORING LONG‐TERM POTENTIATION IMPAIRED BY AMYLOID‐BETA OLIGOMERS: COMPARISON OF A BROADLY‐SPECIFIC ANTI AMYLOID‐BETA NANOBODY AND A MONOMER‐SPECIFIC ANTIBODY

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