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Dose/exposure–response modeling in dose titration trials: Overcoming the titration paradox

CPT: pharmacometrics and systems pharmacology, 2022-12, Vol.11 (12), p.1592-1603

2022

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Pharmacokinetic and pharmacodynamic properties of once‐weekly insulin icodec in individuals with type 1 diabetes

Diabetes, obesity & metabolism, 2024-05, Vol.26 (5), p.1941-1949

2024

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Response to “mixed‐effects models and the drug titration paradox”

CPT: pharmacometrics and systems pharmacology, 2023-04, Vol.12 (4), p.430-431

2023

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Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing

BMJ open diabetes research & care, 2021-08, Vol.9 (1), p.e002301

2021

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Pharmacokinetic and Pharmacodynamic Characteristics of Insulin Icodec After Subcutaneous Administration in the Thigh, Abdomen or Upper Arm in Individuals with Type 2 Diabetes Mellitus

Clinical drug investigation, 2023-02, Vol.43 (2), p.119-127

2023

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Considerations for Industry—Preparing for the FDA Model‐Informed Drug Development (MIDD) Paired Meeting Program

Clinical pharmacology and therapeutics, 2024-08, Vol.116 (2), p.282-288

2024

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Parameter estimation in stochastic grey-box models

Automatica (Oxford), 2004-02, Vol.40 (2), p.225-237

2004

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Insulin degludec's ultra-long pharmacokinetic properties observed in adults are retained in children and adolescents with type 1 diabetes

Pediatric diabetes, 2014-02, Vol.15 (1), p.27-33

2014

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Population stochastic modelling (PSM)—An R package for mixed-effects models based on stochastic differential equations

Computer methods and programs in biomedicine, 2009-06, Vol.94 (3), p.279-289

2009

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A method for systematic improvement of stochastic grey-box models

Computers & chemical engineering, 2004-07, Vol.28 (8), p.1431-1449

2004

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Clearance of rFVIIa and NN1731 after intravenous administration to Beagle dogs

European journal of pharmaceutical sciences, 2011-04, Vol.42 (5), p.578-583

2011

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Insulin degludec's ultra-long pharmacokinetic properties observed in adults are retained in children and adolescents with type 1 diabetes: Insulin degludec in children/adolescents

Pediatric diabetes, 2014-02, Vol.15 (1), p.27-33

2014

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Using stochastic differential equations for PK/PD model development

Journal of pharmacokinetics and pharmacodynamics, 2005-02, Vol.32 (1), p.109-141

2005

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An investigation of some tools for process model indentification for prediction

Computer Aided Chemical Engineering, 2003, Vol.16, p.41-62

2003

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Computer aided continuous time stochastic process modelling

Computer Aided Chemical Engineering, 2001, Vol.9, p.189-194

2001

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Developing phenomena models from experimental data

Computer Aided Chemical Engineering, 2003, Vol.14, p.1091-1096

2003

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A unified framework for systematic model improvement

Computer Aided Chemical Engineering, 2003, Vol.15, p.1292-1297

2003

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Using continuous time stochastic modelling and nonparametric statistics to improve the quality of first principles models

Computer Aided Chemical Engineering, 2002, Vol.10, p.901-906

2002

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Stochastic Grey-Box Modelling as a Tool for Improving the Quality of First Engineering Principles Models

IFAC Proceedings Volumes, 2004-01, Vol.37 (1), p.143-148

2004

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Identification of continuous time models using discrete time data

IFAC Proceedings Volumes, 2003-09, Vol.36 (16), p.615-620

2003

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Dose/exposure–response modeling in dose titration trials: Overcoming the titration paradox

Pharmacokinetic and pharmacodynamic properties of once‐weekly insulin icodec in individuals with type 1 diabetes

Response to “mixed‐effects models and the drug titration paradox”

Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing

Pharmacokinetic and Pharmacodynamic Characteristics of Insulin Icodec After Subcutaneous Administration in the Thigh, Abdomen or Upper Arm in Individuals with Type 2 Diabetes Mellitus

Considerations for Industry—Preparing for the FDA Model‐Informed Drug Development (MIDD) Paired Meeting Program

Parameter estimation in stochastic grey-box models

Insulin degludec's ultra-long pharmacokinetic properties observed in adults are retained in children and adolescents with type 1 diabetes

Population stochastic modelling (PSM)—An R package for mixed-effects models based on stochastic differential equations

A method for systematic improvement of stochastic grey-box models

Clearance of rFVIIa and NN1731 after intravenous administration to Beagle dogs

Insulin degludec's ultra-long pharmacokinetic properties observed in adults are retained in children and adolescents with type 1 diabetes: Insulin degludec in children/adolescents

Using stochastic differential equations for PK/PD model development

An investigation of some tools for process model indentification for prediction

Computer aided continuous time stochastic process modelling

Developing phenomena models from experimental data

A unified framework for systematic model improvement

Using continuous time stochastic modelling and nonparametric statistics to improve the quality of first principles models

Stochastic Grey-Box Modelling as a Tool for Improving the Quality of First Engineering Principles Models

Identification of continuous time models using discrete time data

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