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Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics

Nature reviews. Endocrinology, 2020-04, Vol.16 (4), p.202-212

2020

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Evolution of pharmacological obesity treatments: focus on adverse side-effect profiles

Diabetes, obesity & metabolism, 2016-06, Vol.18 (6), p.558-570

2016

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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Nature genetics, 2019-11, Vol.51 (11), p.1596-1606

2019

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Insulin resistance: a risk marker for disease and disability in the older person

Diabetic medicine, 2013-05, Vol.30 (5), p.535-548

2013

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PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development

Nature communications, 2023-09, Vol.14 (1), p.6119-19, Article 6119

2023

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TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm

PloS one, 2014-12, Vol.9 (12), p.e114275-e114275

2014

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Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression

Diabetologia, 2023-04, Vol.66 (4), p.674-694

2023

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Diabetes medication patient safety incident reports to the National Reporting and Learning Service: the care home setting

Diabetic medicine, 2011-12, Vol.28 (12), p.1537-1540

2011

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Dynamic Ins2 Gene Activity Defines β-Cell Maturity States

Diabetes (New York, N.Y.), 2022-12, Vol.71 (12), p.2612-2631

2022

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Diastolic function is strongly and independently associated with cardiorespiratory fitness in central obesity

Journal of applied physiology (1985), 2010-06, Vol.108 (6), p.1568-1574

2010

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SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models

Diabetologia, 2015-05, Vol.58 (5), p.1013-1023

2015

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Npas4 Is a Novel Activity-Regulated Cytoprotective Factor in Pancreatic β-Cells

Diabetes (New York, N.Y.), 2013-08, Vol.62 (8), p.2808-2820

2013

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Type 2 diabetes, psoriasis and thiazolidinediones

International journal of clinical practice (Esher), 2006-03, Vol.60 (3), p.362-363

2006

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Contraindications to metformin therapy in patients with NIDDM

Diabetes care, 1997-06, Vol.20 (6), p.925-928

1997

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Skeletal muscle microvascular exchange capacity is associated with hyperglycaemia in subjects with central obesity

Diabetic medicine, 2009-11, Vol.26 (11), p.1112-1119

2009

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Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors

Developmental cell, 2017-04, Vol.41 (2), p.129-142.e6

2017

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efficacy of self-monitoring of blood glucose in the management of patients with type 2 diabetes treated with a gliclazide modified release-based regimen. A multicentre, randomized, parallel-group, 6-month evaluation (DINAMIC 1 study)

Diabetes, obesity & metabolism, 2008-12, Vol.10 (12), p.1239-1247

2008

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Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors

Stem cell reports, 2018-12, Vol.11 (6), p.1551-1564

2018

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A regulatory network controls nephrocan expression and midgut patterning

Development (Cambridge), 2014-10, Vol.141 (19), p.3772-3781

2014

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Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering

The lancet. Diabetes & endocrinology, 2021-10, Vol.9 (10), p.708-724

2021

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Comparative tolerability profiles of oral antidiabetic agents

Drug safety, 1994-10, Vol.11 (4), p.223-241

1994

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Sir Harold Himsworth and Insulin insensitivity 75 years on

Diabetic medicine, 2011-12, Vol.28 (12), p.1435-1435

2011

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Electrophysiological Characterization of Inducible Pluripotent Stem Cell–Derived Human β-Like Cells and an SLC30A8 Disease Model

Diabetes (New York, N.Y.), 2024-08, Vol.73 (8), p.1255-1265

2024

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Effect of exogenously administered glucagon versus spontaneous endogenous counter-regulation on glycaemic recovery from insulin-induced hypoglycaemia in patients with type 2 diabetes treated with a novel glucokinase activator, AZD1656, and metformin

Diabetes, obesity & metabolism, 2014-11, Vol.16 (11), p.1096-1101

2014

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TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation

Cell reports (Cambridge), 2019-08, Vol.28 (7), p.1830-1844.e6

2019

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Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics

Evolution of pharmacological obesity treatments: focus on adverse side-effect profiles

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Insulin resistance: a risk marker for disease and disability in the older person

PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development

TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm

Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression

Diabetes medication patient safety incident reports to the National Reporting and Learning Service: the care home setting

Dynamic Ins2 Gene Activity Defines β-Cell Maturity States

Diastolic function is strongly and independently associated with cardiorespiratory fitness in central obesity

SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models

Npas4 Is a Novel Activity-Regulated Cytoprotective Factor in Pancreatic β-Cells

Type 2 diabetes, psoriasis and thiazolidinediones

Contraindications to metformin therapy in patients with NIDDM

Skeletal muscle microvascular exchange capacity is associated with hyperglycaemia in subjects with central obesity

Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors

efficacy of self-monitoring of blood glucose in the management of patients with type 2 diabetes treated with a gliclazide modified release-based regimen. A multicentre, randomized, parallel-group, 6-month evaluation (DINAMIC 1 study)

Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors

A regulatory network controls nephrocan expression and midgut patterning

Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering

Comparative tolerability profiles of oral antidiabetic agents

Sir Harold Himsworth and Insulin insensitivity 75 years on

Electrophysiological Characterization of Inducible Pluripotent Stem Cell–Derived Human β-Like Cells and an SLC30A8 Disease Model

Effect of exogenously administered glucagon versus spontaneous endogenous counter-regulation on glycaemic recovery from insulin-induced hypoglycaemia in patients with type 2 diabetes treated with a novel glucokinase activator, AZD1656, and metformin

TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation

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