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The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics

Scientific reports, 2020-10, Vol.10 (1), p.17356-17356, Article 17356

2020

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Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16901-16906

2014

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The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain

Nature communications, 2022-10, Vol.13 (1), p.6113-6113, Article 6113

2022

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Design, Synthesis and Functional Analysis of Dansylated Polytheonamide Mimic: An Artificial Peptide Ion Channel

Journal of the American Chemical Society, 2012-08, Vol.134 (34), p.14011-14018

2012

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Identifying Acute Cardiac Hazard in Early Drug Discovery Using a Calcium Transient High-Throughput Assay in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Frontiers in physiology, 2022-04, Vol.13, p.838435-838435

2022

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Development of a new hazard scoring system in primary neuronal cell cultures for drug-induced acute neuronal toxicity identification in early drug discovery

Frontiers in pharmacology, 2024-05, Vol.15, p.1308547

2024

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Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease

Molecular neurodegeneration, 2024-04, Vol.19 (1), p.37-37, Article 37

2024

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Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (30), p.12313-12318

2011

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Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system

Biosensors & bioelectronics, 2014-09, Vol.59, p.174-183

2014

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Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies

Stem cell research, 2021-07, Vol.54, p.102386-102386, Article 102386

2021

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Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes

Lab on a chip, 2008-01, Vol.8 (4), p.587-595

2008

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The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose

Biomolecules (Basel, Switzerland), 2023-09, Vol.13 (9), p.1355

2023

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SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System

Stem cell reviews and reports, 2021-10, Vol.17 (5), p.1855-1873

2021

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High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures

Cells (Basel, Switzerland), 2023-03, Vol.12 (6), p.958

2023

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Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching

The Journal of biological chemistry, 2015-05, Vol.290 (20), p.12964-12974

2015

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Port-a-patch and patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology

Combinatorial chemistry & high throughput screening, 2009-01, Vol.12 (1), p.24-37

2009

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The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes

Journal of structural biology, 2009-10, Vol.168 (1), p.168-176

2009

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The translational discrepancy in the assessment of seizure risk for antidepressants and antipsychotics

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106772, Article 106772

2020

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Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons

European journal of pharmacology, 2019-09, Vol.858, p.172474-172474, Article 172474

2019

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Role of Kv7.2/Kv7.3 and M 1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons

European journal of pharmacology, 2019-09, Vol.858, p.172474

2019

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Seizure-induced Torsades de pointes:In a canine drug-induced long-QT1 model

Journal of pharmacological and toxicological methods, 2021-09, Vol.111, p.107086-107086, Article 107086

2021

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Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?

European journal of pharmacology, 2022-09, Vol.931, p.175189-175189, Article 175189

2022

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Ready-to-use adherent hiPSC-derived neural co-cultures by vitrification

Cryobiology, 2022-12, Vol.109, p.49

2022

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Are human iPSC-derived neurons a good tool to detect seizurogenic drugs?

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain

The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain

Design, Synthesis and Functional Analysis of Dansylated Polytheonamide Mimic: An Artificial Peptide Ion Channel

Identifying Acute Cardiac Hazard in Early Drug Discovery Using a Calcium Transient High-Throughput Assay in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Development of a new hazard scoring system in primary neuronal cell cultures for drug-induced acute neuronal toxicity identification in early drug discovery

Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease

Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins

Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system

Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies

Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes

The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose

SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System

High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures

Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching

Port-a-patch and patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology

The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes

The translational discrepancy in the assessment of seizure risk for antidepressants and antipsychotics

Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons

Role of Kv7.2/Kv7.3 and M 1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons

Seizure-induced Torsades de pointes:In a canine drug-induced long-QT1 model

Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?

Ready-to-use adherent hiPSC-derived neural co-cultures by vitrification

Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration

Are human iPSC-derived neurons a good tool to detect seizurogenic drugs?

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