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Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial

Molecular therapy, 2017-12, Vol.25 (12), p.2620-2634

2017

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Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

BMC cancer, 2012-03, Vol.12 (1), p.99-99, Article 99

2012

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A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol

BMC cancer, 2017-08, Vol.17 (1), p.576-576, Article 576

2017

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Stability and safety key factors of the oncolytic protoparvovirus H-1 from manufacturing to human application

Applied microbiology and biotechnology, 2023-08, Vol.107 (15), p.4777-4787

2023

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Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Clinical cancer research, 2021-10, Vol.27 (20), p.5546-5556

2021

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Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos

Biology of reproduction, 2003, Vol.68 (1), p.60-66

2003

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Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud

Development (Cambridge), 2003-12, Vol.130 (24), p.6037-6047

2003

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First combined intravenous and intracerebral application of an oncolytic virus, parvovirus h-1, in a phase I/IIa clinical trial in patients with recurrent glioblastoma multiforme (ParvOryx01)

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.TPS2111-TPS2111

2014

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Bioavailability, Biodistribution, and CNS Toxicity of Clinical-Grade Parvovirus H1 after Intravenous and Intracerebral Injection in Rats

Comparative medicine, 2015-02, Vol.65 (1), p.36-45

2015

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ET-21COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

Neuro-oncology (Charlottesville, Va.), 2014-11, Vol.16 (Suppl 5), p.v83-v84

2014

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Pathology, Organ Distribution, and Immune Response after Single and Repeated Intravenous Injection of Rats with Clinical-Grade Parvovirus H1

Comparative medicine, 2015-02, Vol.65 (1), p.23-35

2015

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ET-21 COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

Neuro-oncology (Charlottesville, Va.), 2014-11, Vol.16 (suppl 5), p.v83-v84

2014

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Insulin-like Growth Factor-Binding Protein-5 Inhibits Growth and Induces Differentiation of Mouse Osteosarcoma Cells

Biochemical and biophysical research communications, 2001-10, Vol.288 (2), p.435-442

2001

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Overexpression of Insulin-like Growth Factor-II in Mouse Embryonic Stem Cells Promotes Myogenic Differentiation

Biochemical and biophysical research communications, 2000-11, Vol.277 (3), p.631-638

2000

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Developmental Regulation of Hyaluronan-Binding Protein (RHAMM/IHABP) Expression in Early Bovine Embryos1

Biology of reproduction, 2003-01, Vol.68 (1), p.60-66

2003

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Large‐Scale N‐Ethyl‐N‐Nitrosourea Mutagenesis of Mice – from Phenotypes to Genes

Experimental physiology, 2000-11, Vol.85 (6), p.635-643

2000

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Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice

Growth hormone & IGF research, 2002-02, Vol.12 (1), p.69-79

2002

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Identification and characterization of foot-and-mouth disease virus O1 Burgwedel/1987 as an intertypic recombinant

Journal of general virology, 1992-03, Vol.73 (3), p.613-619

1992

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Large-scale N-ethyl-N-nitrosourea mutagenesis of mice - from phenotypes to genes

Experimental physiology, 2000-11, Vol.85 (6), p.635-643, Article S0958067000020947

2000

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Foot-and-mouth disease virus O1Lombardy is biochemically related to O2 isolates

Virus genes, 1991-07, Vol.5 (3), p.255-266

1991

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P XV.3 The DNA damaging antiandrogen cyproterone acetate is mutagenic in the liver of transgenic Big Blue rats

Mutation research, 1997-09, Vol.379 (1), p.S146-S146

1997

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Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol

Stability and safety key factors of the oncolytic protoparvovirus H-1 from manufacturing to human application

Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos

Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud

First combined intravenous and intracerebral application of an oncolytic virus, parvovirus h-1, in a phase I/IIa clinical trial in patients with recurrent glioblastoma multiforme (ParvOryx01)

Bioavailability, Biodistribution, and CNS Toxicity of Clinical-Grade Parvovirus H1 after Intravenous and Intracerebral Injection in Rats

ET-21COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

Pathology, Organ Distribution, and Immune Response after Single and Repeated Intravenous Injection of Rats with Clinical-Grade Parvovirus H1

ET-21 COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

Insulin-like Growth Factor-Binding Protein-5 Inhibits Growth and Induces Differentiation of Mouse Osteosarcoma Cells

Overexpression of Insulin-like Growth Factor-II in Mouse Embryonic Stem Cells Promotes Myogenic Differentiation

Developmental Regulation of Hyaluronan-Binding Protein (RHAMM/IHABP) Expression in Early Bovine Embryos1

Large‐Scale N‐Ethyl‐N‐Nitrosourea Mutagenesis of Mice – from Phenotypes to Genes

Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice

Identification and characterization of foot-and-mouth disease virus O1 Burgwedel/1987 as an intertypic recombinant

Large-scale N-ethyl-N-nitrosourea mutagenesis of mice - from phenotypes to genes

Foot-and-mouth disease virus O1Lombardy is biochemically related to O2 isolates

P XV.3 The DNA damaging antiandrogen cyproterone acetate is mutagenic in the liver of transgenic Big Blue rats

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