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The Efficacy of Aprotinin Combinations with Selected Antiviral Drugs in Mouse Models of Influenza Pneumonia and Coronavirus Infection Caused by SARS-CoV-2

Molecules (Basel, Switzerland), 2022-08, Vol.27 (15), p.4975

2022

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Effect of Aprotinin and Avifavir® Combination Therapy for Moderate COVID-19 Patients

Viruses, 2021-06, Vol.13 (7), p.1253

2021

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Methylation of Methyl 4-Hydroxy-2-thioxo-1,2-dihydroquinoline-3-carboxylate: Synthetic, Crystallographic, and Molecular Docking Studies

Molecules (Basel, Switzerland), 2020-09, Vol.25 (18), p.4238

2020

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Safety and efficacy of aviandr in patients with generalized anxiety disorder: A multicenter, randomized, double-blind, placebo-controlled, dose-finding, pilot study

Journal of psychiatric research, 2021-11, Vol.143, p.436-444

2021

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AVIFAVIR for Treatment of Patients With Moderate Coronavirus Disease 2019 (COVID-19): Interim Results of a Phase II/III Multicenter Randomized Clinical Trial

Clinical infectious diseases, 2021-08, Vol.73 (3), p.531-534

2021

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Crystal structure of the non-steroidal anti-inflammatory drug (NSAID) tolmetin sodium

Acta crystallographica. Section E, Crystallographic communications, 2021-02, Vol.77 (Pt 2), p.134-137

2021

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Synthesis, X-Ray Crystal Structure, Hirshfeld Surface Analysis, and Molecular Docking Study of Novel Hepatitis B (HBV) Inhibitor: 8-Fluoro-5-(4-fluorobenzyl)-3-(2-methoxybenzyl)-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one

Crystals (Basel), 2019-08, Vol.9 (8), p.379

2019

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Synthesis, X-ray crystal structure, Hirshfeld surface analysis, and molecular docking study of novel inhibitor of hepatitis B: methyl 4-fluoro-3-(morpholinosulfonyl)benzo[b]thiophene-2-carboxylate

Heliyon, 2019-11, Vol.5 (11), p.e02738-e02738, Article e02738

2019

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Novel One-Pot Synthesis of Methyl 4-Hydroxy-2-thioxo-1,2-dihydroquinoline-3-carboxylate: Synthetic and Crystallographic Studies

MolBank, 2019-12, Vol.2019 (4), p.M1085

2019

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Synthesis, inhibitory activity and oral dosing formulation of AV5124, the structural analogue of influenza virus endonuclease inhibitor baloxavir

Journal of antimicrobial chemotherapy, 2021-03, Vol.76 (4), p.1010-1018

2021

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Non-rigid Diarylmethyl Analogs of Baloxavir as Cap-Dependent Endonuclease Inhibitors of Influenza Viruses

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9403-9420

2020

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Synthesis, biological evaluation and in silico modeling of novel integrase strand transfer inhibitors (INSTIs)

European journal of medicinal chemistry, 2020-03, Vol.189, p.112064-112064, Article 112064

2020

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Synthesis, biological evaluation and in silico modeling of novel pan-genotypic NS5A inhibitors

Bioorganic & medicinal chemistry, 2020-10, Vol.28 (20), p.115716-115716, Article 115716

2020

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Blastic Plasmacytoid Dendritic Cell Neoplasm

Sultan Qaboos University medical journal, 2024-08, Vol.24 (3), p.415-417

2024

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Design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists

European journal of medicinal chemistry, 2015-06, Vol.99, p.51-66

2015

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Crystal structure, Hirshfeld analysis and a molecular docking study of a new inhibitor of the Hepatitis B virus (HBV): ethyl 5-methyl-1,1-dioxo-2-{[5-(pentan-3-yl)-1,2,4-oxadiazol-3-yl]methyl}-2H-1,2,6-thiadiazine-4-carboxylate

Acta crystallographica. Section E, Crystallographic communications, 2020-01, Vol.76 (1), p.12-17

2020

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Discovery of Novel Highly Potent Hepatitis C Virus NS5A Inhibitor (AV4025)

Journal of medicinal chemistry, 2014-09, Vol.57 (18), p.7716-7730

2014

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Highly sensitive field test lateral flow immunodiagnostics of PVX infection

Applied microbiology and biotechnology, 2012, Vol.93 (1), p.179-189

2012

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Synthesis of 7-arylimidazo[1,2-a]pyrazin-8(7H)-one derivatives

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2019-05, Vol.55 (4-5), p.386-391

2019

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(1 R ,3 S )-3-(1 H -Benzo[ d ]imidazol-2-yl)-1,2,2-tri-methyl-cyclo-pentane-1-carb-oxy-lic acid as a new anti-diabetic active pharmaceutical ingredient

Acta crystallographica. Section E, Crystallographic communications, 2020-09, Vol.76 (Pt 9), p.1407-1411

2020

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(1 R ,3 S )-3-(1 H -Benzo[ d ]imidazol-2-yl)-1,2,2-trimethylcyclopentane-1-carboxylic acid as a new anti-diabetic active pharmaceutical ingredient

Acta crystallographica. Section E, Crystallographic communications, 2020-09, Vol.76 (9), p.1407-1411

2020

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Crystal structure, Hirshfeld analysis and a mol-ecular docking study of a new inhibitor of the Hepatitis B virus (HBV): ethyl 5-methyl-1,1-dioxo-2-{[5-(pentan-3-yl)-1,2,4-oxa-diazol-3-yl]meth-yl}-2H-1,2,6-thia-diazine-4-carboxyl-ate

Acta crystallographica. Section E, Crystallographic communications, 2020-01, Vol.76 (Pt 1), p.12-17

2020

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Synthesis, Single Crystal X-Ray Analysis, Prediction and Study of Pharmacological Activity of 4-(1H-Benzo[d]imidazol-2-yl)-1-Phenyl-1H-1,2,3-triazol-5-Amine and Its Solvates

Crystals (Basel), 2019-12, Vol.9 (12), p.644

2019

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Novel aryl and heteroaryl substituted N-[3-(4-phenylpiperazin-1-yl)propyl]-1,2,4-oxadiazole-5-carboxamides as selective GSK-3 inhibitors

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (12), p.3661-3666

2008

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Preclinical Development of ONC1-13B, Novel Antiandrogen for Prostate Cancer Treatment

Journal of Cancer, 2014-01, Vol.5 (2), p.133-142

2014

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The Efficacy of Aprotinin Combinations with Selected Antiviral Drugs in Mouse Models of Influenza Pneumonia and Coronavirus Infection Caused by SARS-CoV-2

Effect of Aprotinin and Avifavir® Combination Therapy for Moderate COVID-19 Patients

Methylation of Methyl 4-Hydroxy-2-thioxo-1,2-dihydroquinoline-3-carboxylate: Synthetic, Crystallographic, and Molecular Docking Studies

Safety and efficacy of aviandr in patients with generalized anxiety disorder: A multicenter, randomized, double-blind, placebo-controlled, dose-finding, pilot study

AVIFAVIR for Treatment of Patients With Moderate Coronavirus Disease 2019 (COVID-19): Interim Results of a Phase II/III Multicenter Randomized Clinical Trial

Crystal structure of the non-steroidal anti-inflammatory drug (NSAID) tolmetin sodium

Synthesis, X-Ray Crystal Structure, Hirshfeld Surface Analysis, and Molecular Docking Study of Novel Hepatitis B (HBV) Inhibitor: 8-Fluoro-5-(4-fluorobenzyl)-3-(2-methoxybenzyl)-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one

Synthesis, X-ray crystal structure, Hirshfeld surface analysis, and molecular docking study of novel inhibitor of hepatitis B: methyl 4-fluoro-3-(morpholinosulfonyl)benzo[b]thiophene-2-carboxylate

Novel One-Pot Synthesis of Methyl 4-Hydroxy-2-thioxo-1,2-dihydroquinoline-3-carboxylate: Synthetic and Crystallographic Studies

Synthesis, inhibitory activity and oral dosing formulation of AV5124, the structural analogue of influenza virus endonuclease inhibitor baloxavir

Non-rigid Diarylmethyl Analogs of Baloxavir as Cap-Dependent Endonuclease Inhibitors of Influenza Viruses

Synthesis, biological evaluation and in silico modeling of novel integrase strand transfer inhibitors (INSTIs)

Synthesis, biological evaluation and in silico modeling of novel pan-genotypic NS5A inhibitors

Blastic Plasmacytoid Dendritic Cell Neoplasm

Design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists

Crystal structure, Hirshfeld analysis and a molecular docking study of a new inhibitor of the Hepatitis B virus (HBV): ethyl 5-methyl-1,1-dioxo-2-{[5-(pentan-3-yl)-1,2,4-oxadiazol-3-yl]methyl}-2H-1,2,6-thiadiazine-4-carboxylate

Discovery of Novel Highly Potent Hepatitis C Virus NS5A Inhibitor (AV4025)

Highly sensitive field test lateral flow immunodiagnostics of PVX infection

Synthesis of 7-arylimidazo[1,2-a]pyrazin-8(7H)-one derivatives

(1 R ,3 S )-3-(1 H -Benzo[ d ]imidazol-2-yl)-1,2,2-tri-methyl-cyclo-pentane-1-carb-oxy-lic acid as a new anti-diabetic active pharmaceutical ingredient

(1 R ,3 S )-3-(1 H -Benzo[ d ]imidazol-2-yl)-1,2,2-trimethylcyclopentane-1-carboxylic acid as a new anti-diabetic active pharmaceutical ingredient

Crystal structure, Hirshfeld analysis and a mol-ecular docking study of a new inhibitor of the Hepatitis B virus (HBV): ethyl 5-methyl-1,1-dioxo-2-{[5-(pentan-3-yl)-1,2,4-oxa-diazol-3-yl]meth-yl}-2H-1,2,6-thia-diazine-4-carboxyl-ate

Synthesis, Single Crystal X-Ray Analysis, Prediction and Study of Pharmacological Activity of 4-(1H-Benzo[d]imidazol-2-yl)-1-Phenyl-1H-1,2,3-triazol-5-Amine and Its Solvates

Novel aryl and heteroaryl substituted N-[3-(4-phenylpiperazin-1-yl)propyl]-1,2,4-oxadiazole-5-carboxamides as selective GSK-3 inhibitors

Preclinical Development of ONC1-13B, Novel Antiandrogen for Prostate Cancer Treatment

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