UB Paderborn / Katalog / Suche / in CDI

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

Molecular microbiology, 2000-02, Vol.35 (3), p.542-552

2000

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2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

Journal of medicinal chemistry, 2001-02, Vol.44 (4), p.548-565

2001

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2,3-Diphenyl-1,4-Naphthoquinone: A Potential Chemotherapeutic Agent Against Trypanosoma cruzi

The Journal of parasitology, 2009-04, Vol.95 (2), p.461-466

2009

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(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes Are Irreversible Inhibitors of Trypanosoma cruzi Trypanothione Reductase But Not of Human Glutathione Reductase

Journal of medicinal chemistry, 2000-12, Vol.43 (25), p.4812-4821

2000

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Inhibition of Trypanosoma cruzi Trypanothione Reductase by Acridines: Kinetic Studies and Structure−Activity Relationships

Journal of medicinal chemistry, 1999-12, Vol.42 (26), p.5448-5454

1999

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Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase

Biochemical pharmacology, 1999-12, Vol.58 (11), p.1791-1799

1999

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Thiol-based redox metabolism of protozoan parasites

Trends in parasitology, 2003-07, Vol.19 (7), p.320-328

2003

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Ajoene Is an Inhibitor and Subversive Substrate of Human Glutathione Reductase and Trypanosoma cruzi Trypanothione Reductase: Crystallographic, Kinetic, and Spectroscopic Studies

Journal of medicinal chemistry, 1999-02, Vol.42 (3), p.364-372

1999

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Glyoxalase II of African Trypanosomes Is Trypanothione-dependent

The Journal of biological chemistry, 2004-05, Vol.279 (21), p.22209-22217

2004

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Synthetic single and double aza-scorpiand macrocycles acting as inhibitors of the antioxidant enzymes iron superoxide dismutase and trypanothione reductase in Trypanosoma cruzi with promising results in a murine model

RSC advances, 2014-01, Vol.4 (110), p.65108-65120

2014

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The parasite-specific trypanothione metabolism of trypanosoma and leishmania

Biological chemistry, 2003-04, Vol.384 (4), p.539-549

2003

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Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells

Molecular bioSystems, 2012-04, Vol.8 (4), p.1311-1318

2012

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A Second Class of Peroxidases Linked to the Trypanothione Metabolism

The Journal of biological chemistry, 2003-02, Vol.278 (9), p.6809-6815

2003

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Enzymatic reduction studies of nitroheterocycles

Biochemical pharmacology, 1999-03, Vol.57 (5), p.549-557

1999

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Functional and Physicochemical Characterization of the Thioredoxin System in Trypanosoma brucei

The Journal of biological chemistry, 2003-11, Vol.278 (47), p.46329-46336

2003

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The Crystal Structure of Plasmodium falciparum Glutamate Dehydrogenase, a Putative Target for Novel Antimalarial Drugs

Journal of molecular biology, 2005-06, Vol.349 (3), p.597-607

2005

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Trypanothione-dependent Synthesis of Deoxyribonucleotides by Trypanosoma brucei Ribonucleotide Reductase

The Journal of biological chemistry, 2001-04, Vol.276 (14), p.10602-10606

2001

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Catalytic Properties, Thiol pK Value, and Redox Potential of Trypanosoma brucei Tryparedoxin

The Journal of biological chemistry, 2002-05, Vol.277 (20), p.17548-17555

2002

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Dithiol Proteins as Guardians of the Intracellular Redox Milieu in Parasites: Old and New Drug Targets in Trypanosomes and Malaria-Causing Plasmodia

Angewandte Chemie (International ed.), 2005-01, Vol.44 (5), p.690-715

2005

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Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei

Bioorganic & medicinal chemistry letters, 2017-01, Vol.27 (1), p.45-50

2017

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Trypanosoma brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes

FEBS letters, 1998-07, Vol.431 (3), p.381-385

1998

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Identification and Functional Characterization of Thioredoxin from Trypanosoma brucei brucei

The Journal of biological chemistry, 2000-03, Vol.275 (11), p.7547-7552

2000

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Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

Biochemical journal, 2007-02, Vol.402 (1), p.43-49

2007

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Growth inhibition of bloodstream forms of Trypanosoma brucei by the iron chelator deferoxamine

International journal for parasitology, 2002-04, Vol.32 (4), p.473-479

2002

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The Dithiol Glutaredoxins of African Trypanosomes Have Distinct Roles and Are Closely Linked to the Unique Trypanothione Metabolism

The Journal of biological chemistry, 2010-11, Vol.285 (45), p.35224-35237

2010

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Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

2,3-Diphenyl-1,4-Naphthoquinone: A Potential Chemotherapeutic Agent Against Trypanosoma cruzi

(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes Are Irreversible Inhibitors of Trypanosoma cruzi Trypanothione Reductase But Not of Human Glutathione Reductase

Inhibition of Trypanosoma cruzi Trypanothione Reductase by Acridines: Kinetic Studies and Structure−Activity Relationships

Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase

Thiol-based redox metabolism of protozoan parasites

Ajoene Is an Inhibitor and Subversive Substrate of Human Glutathione Reductase and Trypanosoma cruzi Trypanothione Reductase: Crystallographic, Kinetic, and Spectroscopic Studies

Glyoxalase II of African Trypanosomes Is Trypanothione-dependent

Synthetic single and double aza-scorpiand macrocycles acting as inhibitors of the antioxidant enzymes iron superoxide dismutase and trypanothione reductase in Trypanosoma cruzi with promising results in a murine model

The parasite-specific trypanothione metabolism of trypanosoma and leishmania

Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells

A Second Class of Peroxidases Linked to the Trypanothione Metabolism

Enzymatic reduction studies of nitroheterocycles

Functional and Physicochemical Characterization of the Thioredoxin System in Trypanosoma brucei

The Crystal Structure of Plasmodium falciparum Glutamate Dehydrogenase, a Putative Target for Novel Antimalarial Drugs

Trypanothione-dependent Synthesis of Deoxyribonucleotides by Trypanosoma brucei Ribonucleotide Reductase

Catalytic Properties, Thiol pK Value, and Redox Potential of Trypanosoma brucei Tryparedoxin

Dithiol Proteins as Guardians of the Intracellular Redox Milieu in Parasites: Old and New Drug Targets in Trypanosomes and Malaria-Causing Plasmodia

Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei

Trypanosoma brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes

Identification and Functional Characterization of Thioredoxin from Trypanosoma brucei brucei

Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

Growth inhibition of bloodstream forms of Trypanosoma brucei by the iron chelator deferoxamine

The Dithiol Glutaredoxins of African Trypanosomes Have Distinct Roles and Are Closely Linked to the Unique Trypanothione Metabolism

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