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Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450

Xenobiotica, 2000, Vol.30 (4), p.327-343

2000

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Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site

Biochemistry (Easton), 1994-05, Vol.33 (21), p.6450-6455

1994

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Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone

Carcinogenesis (New York), 1997, Vol.18 (1), p.207-214

1997

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Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor -Mediated Apoptosis

Drug metabolism and disposition, 2016-04, Vol.44 (5), p.720-731

2016

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Differential irreversible insertion of protein kinase C into phospholipid vesicles by phorbol esters and related activators

The Journal of biological chemistry, 1992-10, Vol.267 (29), p.20878-20886

1992

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Differential Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Mice Humanized for CYP1A1 and CYP1A2

Chemical research in toxicology, 2005-09, Vol.18 (9), p.1471-1478

2005

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Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

European journal of pharmacology, 2000-04, Vol.394 (2), p.199-209

2000

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Metabolic activation of the potent carcinogen dibenzo[a, l]pyrene by human recombinant cytochromes P450, lung and liver microsomes

Carcinogenesis (New York), 1996-11, Vol.17 (11), p.2429-2433

1996

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Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Carcinogenesis (New York), 2007-03, Vol.28 (3), p.732-737

2007

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Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism

Drug metabolism and disposition, 1999-01, Vol.27 (1), p.102

1999

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Inhibitory Monoclonal Antibody to Human Cytochrome P450 2B6

Biochemical pharmacology, 1998-05, Vol.55 (10), p.1633-1640

1998

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Inhibitory and non-inhibitory monoclonal antibodies to human cytochrome P450 3A3/4

Biochemical pharmacology, 1995-11, Vol.50 (11), p.1841-1850

1995

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An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys

Xenobiotica, 2000-06, Vol.30 (6), p.619-625

2000

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A Metabolomic Approach to the Metabolism of the Areca Nut Alkaloids Arecoline and Arecaidine in the Mouse

Chemical research in toxicology, 2006-06, Vol.19 (6), p.818-827

2006

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Inhibitory monoclonal antibodies to human cytochrome P450 2D6

Biochemical pharmacology, 1997-07, Vol.54 (1), p.15-17

1997

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Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance acetaminophen-induced toxicity

Drug metabolism and disposition, 2009-08, Vol.37 (8), p.1611

2009

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Metabolism of melatonin by human cytochromes p450

Drug metabolism and disposition, 2005-04, Vol.33 (4), p.489

2005

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Identification of Novel Toxicity-associated Metabolites by Metabolomics and Mass Isotopomer Analysis of Acetaminophen Metabolism in Wild-type and Cyp2e1-null Mice

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.4543-4559

2008

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Monoclonal antibodies specific and inhibitory to human cytochromes P450 2C8, 2C9, and 2C19

Drug metabolism and disposition, 2001-11, Vol.29 (11), p.1410

2001

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Inhibitory monoclonal antibodies to human cytochrome P450 enzymes: a new avenue for drug discovery

Trends in pharmacological sciences (Regular ed.), 1999-11, Vol.20 (11), p.432-438

1999

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A Comprehensive Investigation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach

Chemical research in toxicology, 2007-03, Vol.20 (3), p.531-542

2007

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The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.449

2005

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Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives : enzyme specificity, interindividual distribution and metabolic contribution in human liver

Pharmacogenetics (London), 1998-10, Vol.8 (5), p.391-401

1998

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Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver

Hepatology (Baltimore, Md.), 2005-02, Vol.41 (2), p.336-344

2005

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Metabolic Activation of the Potent Carcinogen Dibenzo[a,h]anthracene by cDNA-Expressed Human Cytochromes P450

Archives of biochemistry and biophysics, 1996-04, Vol.328 (1), p.201-207

1996

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Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450

Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site

Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone

Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor -Mediated Apoptosis

Differential irreversible insertion of protein kinase C into phospholipid vesicles by phorbol esters and related activators

Differential Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Mice Humanized for CYP1A1 and CYP1A2

Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

Metabolic activation of the potent carcinogen dibenzo[a, l]pyrene by human recombinant cytochromes P450, lung and liver microsomes

Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism

Inhibitory Monoclonal Antibody to Human Cytochrome P450 2B6

Inhibitory and non-inhibitory monoclonal antibodies to human cytochrome P450 3A3/4

An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys

A Metabolomic Approach to the Metabolism of the Areca Nut Alkaloids Arecoline and Arecaidine in the Mouse

Inhibitory monoclonal antibodies to human cytochrome P450 2D6

Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance acetaminophen-induced toxicity

Metabolism of melatonin by human cytochromes p450

Identification of Novel Toxicity-associated Metabolites by Metabolomics and Mass Isotopomer Analysis of Acetaminophen Metabolism in Wild-type and Cyp2e1-null Mice

Monoclonal antibodies specific and inhibitory to human cytochromes P450 2C8, 2C9, and 2C19

Inhibitory monoclonal antibodies to human cytochrome P450 enzymes: a new avenue for drug discovery

A Comprehensive Investigation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach

The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity

Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives : enzyme specificity, interindividual distribution and metabolic contribution in human liver

Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver

Metabolic Activation of the Potent Carcinogen Dibenzo[a,h]anthracene by cDNA-Expressed Human Cytochromes P450

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