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Molecular basis of inhibition of acid sensing ion channel 1A by diminazene

PloS one, 2018-05, Vol.13 (5), p.e0196894

2018

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Conformational Fine-Tuning of Pore-Forming Peptide Potency and Selectivity

Journal of the American Chemical Society, 2015-12, Vol.137 (51), p.16144-16152

2015

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A deep learning approach to identify gene targets of a therapeutic for human splicing disorders

Nature communications, 2021-06, Vol.12 (1), p.3332-3332, Article 3332

2021

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Determining the mechanism of membrane permeabilizing peptides: Identification of potent, equilibrium pore-formers

Biochimica et biophysica acta, 2012-07, Vol.1818 (7), p.1625-1632

2012

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Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients

npj vaccines, 2023-09, Vol.8 (1), p.141-141, Article 141

2023

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Gain-of-Function Analogues of the Pore-Forming Peptide Melittin Selected by Orthogonal High-Throughput Screening

Journal of the American Chemical Society, 2012-08, Vol.134 (30), p.12732-12741

2012

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Factors associated with myocardial SARS-CoV-2 infection, myocarditis, and cardiac inflammation in patients with COVID-19

Modern pathology, 2021-07, Vol.34 (7), p.1345-1357

2021

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The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization

The Journal of biological chemistry, 2016-05, Vol.291 (21), p.11407-11419

2016

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Independent Contribution of Extracellular Proton Binding Sites to ASIC1a Activation

The Journal of biological chemistry, 2013-11, Vol.288 (48), p.34375-34383

2013

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Selective retinal ganglion cell loss and optic neuropathy in a humanized mouse model of familial dysautonomia

Human molecular genetics, 2022-06, Vol.31 (11), p.1776-1787

2022

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Development of an oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia

American journal of human genetics, 2023-03, Vol.110 (3), p.531-547

2023

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Toward the de novo design of antimicrobial peptides: Lack of correlation between peptide permeabilization of lipid vesicles and antimicrobial, cytolytic, or cytotoxic activity in living cells

Biopolymers, 2014-01, Vol.102 (1), p.1-6

2014

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Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage

Journal of genetics and genomics, 2022-07, Vol.49 (7), p.654-665

2022

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Interactions of Membrane Active Peptides with Planar Supported Bilayers: An Impedance Spectroscopy Study

Langmuir, 2012-04, Vol.28 (14), p.6088-6096

2012

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Synthetic Molecular Evolution of Pore-Forming Peptides by Iterative Combinatorial Library Screening

ACS chemical biology, 2013-04, Vol.8 (4), p.823-831

2013

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Molecular Basis of Inhibition of Acid Sensing Ion Channels by Diminazene

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Functional Coupling between the Finger and Thumb Domains of ASIC1A

Biophysical journal, 2015-01, Vol.108 (2), p.288a-288a

2015

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Finger-Thumb Interdomain Interactions Influence ASIC1a Proton Activation

Biophysical journal, 2014-01, Vol.106 (2), p.153a-153a

2014

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Bulky Substitutions in the Thumb Domain of ASIC1a Restrict Proton-Gating

Biophysical journal, 2013-01, Vol.104 (2), p.270a-270a

2013

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Discovering Highly Potent Pore-Forming Peptides using Synthetic Molecular Evolution

Biophysical journal, 2013-01, Vol.104 (2), p.9a-9a

2013

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High Throughput Screen of Combinatorial Peptide Library for Gain-of-Function and Loss-of-Function Changes to Melittin

Biophysical journal, 2011-02, Vol.100 (3), p.496a-497a

2011

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A New Look at an Old Friend: Novel Insights Into Pore Formation by Alamethicin

Biophysical journal, 2010-01, Vol.98 (3), p.276a-276a

2010

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Mechanisms Of Antimicrobial Peptide Action Determined Using Chemical And Collisional Quenching Assays

Biophysical journal, 2009-02, Vol.96 (3), p.456a-456a

2009

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Interactions of Membrane Active Peptides with Planar Supported Bilayers: an Impedance Spectroscopy Study

Biophysical journal, 2011-02, Vol.100 (3), p.351a-351a

2011

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Membrane-Active Peptides: Stable Pore-Forming or Cell-Penetrating Peptides Selected With Orthogonal High-Throughput Screening

Biophysical journal, 2010-01, Vol.98 (3), p.85a-85a

2010

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Molecular basis of inhibition of acid sensing ion channel 1A by diminazene

Conformational Fine-Tuning of Pore-Forming Peptide Potency and Selectivity

A deep learning approach to identify gene targets of a therapeutic for human splicing disorders

Determining the mechanism of membrane permeabilizing peptides: Identification of potent, equilibrium pore-formers

Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients

Gain-of-Function Analogues of the Pore-Forming Peptide Melittin Selected by Orthogonal High-Throughput Screening

Factors associated with myocardial SARS-CoV-2 infection, myocarditis, and cardiac inflammation in patients with COVID-19

The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization

Independent Contribution of Extracellular Proton Binding Sites to ASIC1a Activation

Selective retinal ganglion cell loss and optic neuropathy in a humanized mouse model of familial dysautonomia

Development of an oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia

Toward the de novo design of antimicrobial peptides: Lack of correlation between peptide permeabilization of lipid vesicles and antimicrobial, cytolytic, or cytotoxic activity in living cells

Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage

Interactions of Membrane Active Peptides with Planar Supported Bilayers: An Impedance Spectroscopy Study

Synthetic Molecular Evolution of Pore-Forming Peptides by Iterative Combinatorial Library Screening

Molecular Basis of Inhibition of Acid Sensing Ion Channels by Diminazene

Functional Coupling between the Finger and Thumb Domains of ASIC1A

Finger-Thumb Interdomain Interactions Influence ASIC1a Proton Activation

Bulky Substitutions in the Thumb Domain of ASIC1a Restrict Proton-Gating

Discovering Highly Potent Pore-Forming Peptides using Synthetic Molecular Evolution

High Throughput Screen of Combinatorial Peptide Library for Gain-of-Function and Loss-of-Function Changes to Melittin

A New Look at an Old Friend: Novel Insights Into Pore Formation by Alamethicin

Mechanisms Of Antimicrobial Peptide Action Determined Using Chemical And Collisional Quenching Assays

Interactions of Membrane Active Peptides with Planar Supported Bilayers: an Impedance Spectroscopy Study

Membrane-Active Peptides: Stable Pore-Forming or Cell-Penetrating Peptides Selected With Orthogonal High-Throughput Screening

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