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S-(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, a reactive metabolite of S-(1,2,2-Trichlorovinyl)-L-cysteine formed in rat liver and kidney microsomes, is a potent nephrotoxicant

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.1095

2007

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Human kidney flavin-containing monooxygenases and their potential roles in cysteine s-conjugate metabolism and nephrotoxicity

The Journal of pharmacology and experimental therapeutics, 2003-01, Vol.304 (1), p.185

2003

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Roles of necrosis, Apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-L-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.1163

2003

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Reduction of l-methionine selenoxide to seleno- l-methionine by endogenous thiols, ascorbic acid, or methimazole

Biochemical pharmacology, 2009-01, Vol.77 (1), p.134-140

2009

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Hydroxymethylvinyl Ketone: A Reactive Michael Acceptor Formed by the Oxidation of 3-Butene-1,2-diol by cDNA-Expressed Human Cytochrome P450s and Mouse, Rat, and Human Liver Microsomes

Chemical research in toxicology, 2001-12, Vol.14 (12), p.1590-1595

2001

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Oxidative Metabolism of Seleno-l-methionine to l-Methionine Selenoxide by Flavin-Containing Monooxygenases

Chemical research in toxicology, 2006-12, Vol.19 (12), p.1643-1649

2006

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Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways

Drug metabolism and disposition, 2001-06, Vol.29 (6), p.830

2001

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Potential roles of flavin-containing monooxygenases in sulfoxidation reactions of l-methionine, N-acetyl- l-methionine and peptides containing l-methionine

Biochimica et biophysica acta, 2005-01, Vol.1703 (2), p.183-189

2005

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Mass spectral analyses of hemoglobin adducts formed after in vitro exposure of erythrocytes to hydroxymethylvinyl ketone

Chemico-biological interactions, 2007-03, Vol.166 (1), p.176-181

2007

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Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavin-containing monooxygenases

Drug metabolism and disposition, 2002-10, Vol.30 (10), p.1137

2002

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Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences

Drug metabolism and disposition, 1998-01, Vol.26 (1), p.12

1998

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Epoxide hydrolase-dependent metabolism of butadiene monoxide to 3-butene-1,2-diol in mouse, rat, and human liver

Drug metabolism and disposition, 1997-08, Vol.25 (8), p.1013

1997

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Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes

Drug metabolism and disposition, 1998-08, Vol.26 (8), p.779

1998

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Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism

Chemico-biological interactions, 2001-06, Vol.135, p.239-248

2001

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Biochemistry of 1,3-butadiene metabolism and its relevance to 1,3-butadiene-induced carcinogenicity

Toxicology (Amsterdam), 1996-10, Vol.113 (1), p.23-30

1996

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Renal Cellular Transport, Metabolism, and Cytotoxicity of S-(6-Purinyl)glutathione, a Prodrug of 6-Mercaptopurine, and Analogues

Biochemical pharmacology, 1997-12, Vol.54 (12), p.1341-1349

1997

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GSH oxidation to GSSG preceded seleno‐L‐methionine cytotoxicity in freshly isolated rat hepatocytes

The FASEB journal, 2007, Vol.21 (6), p.A813-A814

2007

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Oxidation of butadiene monoxide to meso- and (+/-)-diepoxybutane by cDNA-expressed human cytochrome P450s and by mouse, rat, and human liver microsomes: evidence for preferential hydration of meso-diepoxybutane in rat and human liver microsomes

Archives of biochemistry and biophysics, 1997-01, Vol.337 (2), p.176

1997

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Renal and hepatic toxicity of trichloroethylene and its glutathione-derived metabolites in rats and mice: sex-, species-, and tissue-dependent differences

The Journal of pharmacology and experimental therapeutics, 2001-04, Vol.297 (1), p.155

2001

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Oxidation of Butadiene Monoxide tomeso-and (±)-Diepoxybutane by cDNA-Expressed Human Cytochrome P450s and by Mouse, Rat, and Human Liver Microsomes: Evidence for Preferential Hydration ofmeso-Diepoxybutane in Rat and Human Liver Microsomes

Archives of biochemistry and biophysics, 1997-01, Vol.337 (2), p.176-184

1997

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Characterization of the methionine S-oxidase activity of rat liver and kidney microsomes: immunochemical and kinetic evidence for FMO3 being the major catalyst

Archives of biochemistry and biophysics, 1996-09, Vol.333 (1), p.109-116

1996

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Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity

Advances in experimental medicine and biology, 2001, Vol.500, p.93

2001

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Characterization of the MethionineS-Oxidase Activity of Rat Liver and Kidney Microsomes: Immunochemical and Kinetic Evidence for FMO3 Being the Major Catalyst

Archives of biochemistry and biophysics, 1996-09, Vol.333 (1), p.109-116

1996

Volltextzugriff (PDF)

Tube Worm Fossils or Relic Methane Expulsing Conduits?

Palaios, 2009-01, Vol.24 (1), p.41-50

2009

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Duration of work disability: A comparison of self-report and administrative data

American journal of industrial medicine, 2006-05, Vol.49 (5), p.394-401

2006

Volltextzugriff (PDF)

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S-(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, a reactive metabolite of S-(1,2,2-Trichlorovinyl)-L-cysteine formed in rat liver and kidney microsomes, is a potent nephrotoxicant

Human kidney flavin-containing monooxygenases and their potential roles in cysteine s-conjugate metabolism and nephrotoxicity

Roles of necrosis, Apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-L-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells

Reduction of l-methionine selenoxide to seleno- l-methionine by endogenous thiols, ascorbic acid, or methimazole

Hydroxymethylvinyl Ketone: A Reactive Michael Acceptor Formed by the Oxidation of 3-Butene-1,2-diol by cDNA-Expressed Human Cytochrome P450s and Mouse, Rat, and Human Liver Microsomes

Oxidative Metabolism of Seleno-l-methionine to l-Methionine Selenoxide by Flavin-Containing Monooxygenases

Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways

Potential roles of flavin-containing monooxygenases in sulfoxidation reactions of l-methionine, N-acetyl- l-methionine and peptides containing l-methionine

Mass spectral analyses of hemoglobin adducts formed after in vitro exposure of erythrocytes to hydroxymethylvinyl ketone

Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavin-containing monooxygenases

Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences

Epoxide hydrolase-dependent metabolism of butadiene monoxide to 3-butene-1,2-diol in mouse, rat, and human liver

Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes

Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism

Biochemistry of 1,3-butadiene metabolism and its relevance to 1,3-butadiene-induced carcinogenicity

Renal Cellular Transport, Metabolism, and Cytotoxicity of S-(6-Purinyl)glutathione, a Prodrug of 6-Mercaptopurine, and Analogues

GSH oxidation to GSSG preceded seleno‐L‐methionine cytotoxicity in freshly isolated rat hepatocytes

Oxidation of butadiene monoxide to meso- and (+/-)-diepoxybutane by cDNA-expressed human cytochrome P450s and by mouse, rat, and human liver microsomes: evidence for preferential hydration of meso-diepoxybutane in rat and human liver microsomes

Renal and hepatic toxicity of trichloroethylene and its glutathione-derived metabolites in rats and mice: sex-, species-, and tissue-dependent differences

Oxidation of Butadiene Monoxide tomeso-and (±)-Diepoxybutane by cDNA-Expressed Human Cytochrome P450s and by Mouse, Rat, and Human Liver Microsomes: Evidence for Preferential Hydration ofmeso-Diepoxybutane in Rat and Human Liver Microsomes

Characterization of the methionine S-oxidase activity of rat liver and kidney microsomes: immunochemical and kinetic evidence for FMO3 being the major catalyst

Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity

Characterization of the MethionineS-Oxidase Activity of Rat Liver and Kidney Microsomes: Immunochemical and Kinetic Evidence for FMO3 Being the Major Catalyst

Tube Worm Fossils or Relic Methane Expulsing Conduits?

Duration of work disability: A comparison of self-report and administrative data

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